Melanoma Clinical Trials

A listing of Melanoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 261 clinical trials
Evaluating the Effect of Nivolumab for Patients With In-transit Metastases Treated With Isolated Limb Perfusion (NivoILP)

To evaluate safety and the effect of isolated limb perfusion together with nivolumab as a way to increase efficacy and give further insights in early immunological mechanisms. In the first phase Ib part, 20 patients will be enrolled and followed for a minimum of 3 months. An independent data safety …

metastasis
measurable disease
nivolumab
  • 2 views
  • 14 May, 2022
  • 2 locations
CD8+ T Cell Imaging During Pre-surgery Immunotherapy in People With Melanoma

Combination treatment with nivolumab and ipilimumab before surgery may help people with melanoma because the drugs are designed to help the immune system target and destroy cancer cells

ipilimumab
nivolumab
BRAF
measurable disease
stage iii melanoma
  • 0 views
  • 23 Apr, 2022
  • 1 location
CBL0137 in Treating Patients With Advanced Extremity Melanoma or Sarcoma

This phase I trial studies best dose and side effects of CBL0137 in treating patients with extremity melanoma or sarcoma that has spread to other places in the body. Drugs, such as CBL0137, may

  • 0 views
  • 09 Apr, 2022
  • 1 location
IN10018 Monotherapy and Combination Therapy for Metastatic Melanoma

metastatic uveal melanoma and NRAS-mutant metastatic melanoma.

  • 5 views
  • 25 Apr, 2022
  • 5 locations
Fecal Microbial Transplantation Non-Small Cell Lung Cancer and Melanoma (FMT-LUMINATE)

The aim of this study is to assess the anti-tumor activity of FMT administered in combination with ICI therapy.

  • 0 views
  • 12 May, 2022
  • 2 locations
Intratumoral Administration of Daromun in Non-melanoma Skin Cancer Patients (DUNCAN)

following intralesional treatment with L19IL2/L19TNF have been observed in patients with injectable melanoma lesions of stage III or IV, for injected and non-injected lesions. The proposed clinical

melanoma skin
skin cancer
metastasis
carcinoma of skin
cancer
  • 0 views
  • 01 May, 2022
  • 3 locations
Adoptive Transfer of Tumor Infiltrating Lymphocytes for Metastatic Uveal Melanoma

metastatic uveal melanoma will be evaluated. Metastatic uveal melanoma (UM) carries a poor prognosis with estimated survival of 4-6 months. There are no known effective systemic therapies. Metastatic

neutrophil count
clinical protocols
metastasis
alopecia
gilbert's syndrome
  • 30 views
  • 11 May, 2022
  • 1 location
Phase 2 Trial to Evaluate Safety and Efficacy of AU-011 Via Suprachoroidal Administration in Subjects With Primary Indeterminate Lesions and Small Choroidal Melanoma

The primary objective is to assess safety and efficacy of AU-011 via suprachoroidal injection to treat primary indeterminate lesions and small choroidal melanoma.

metastasis
choroid melanoma
  • 0 views
  • 22 Apr, 2022
  • 18 locations
A Study Evaluating Whether Pembrolizumab Alone or in Combination With CMP-001 Improves Efficacy in Patients With Operable Melanoma

This phase II trial studies the effect of pembrolizumab alone or in combination with CMP-001 in treating patients with melanoma that can be treated by surgery (operable). Immunotherapy with

  • 0 views
  • 10 May, 2022
  • 50 locations
A Study to Compare the Administration of Pembrolizumab After Surgery Versus Administration Both Before and After Surgery for High-Risk Melanoma

This phase II trial studies how pembrolizumab works before and after surgery in treating patients with stage III-IV high-risk melanoma. Immunotherapy with monoclonal antibodies, such as

  • 82 views
  • 11 May, 2022
  • 621 locations