Leukemia Clinical Trials

A listing of Leukemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 731 clinical trials
Umbilical Vessel Catheterization Under ECG Monitoring and Guidance

Umbilical venous catheters (UVC) are typically places with poor guidance and some radiological confirmation. Misplacement of the catheter could lead to its placement in other unintended anatomical areas such as the liver or the spleen, which could be detrimental in critically-ill infants. Our study aims at using a more non-invasive …

  • 0 views
  • 30 Jun, 2022
  • 1 location
Genetically Engineered Cells (Anti-CD19/CD20/CD22 CAR T-cells) for the Treatment of Relapsed or Refractory Lymphoid Malignancies

). Lymphoid malignancies eligible for this trial are: non-Hodgkin lymphoma (NHL), acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), and B-prolymphocytic leukemia (B-PLL). T-cells (a type

  • 0 views
  • 27 Jul, 2022
  • 1 location
Myeloablative Allo HSCT With Related or Unrelated Donor for Heme Disorders

This is a Phase II study of allogeneic hematopoietic stem cell transplant (HCT) using a myeloablative preparative regimen (of either total body irradiation (TBI); or, fludarabine/busulfan for patients unable to receive further radiation). followed by a post-transplant graft-versus-host disease (GVHD) prophylaxis regimen of post-transplant cyclophosphamide (PTCy), tacrolimus (Tac), and mycophenolate …

ejection fraction
b-cell small lymphocytic lymphoma
lymphocytic leukemia
multiple myeloma
graft-versus-host disease
  • 58 views
  • 06 May, 2022
  • 1 location
IO-202 as Monotherapy and IO-202 Plus Azacitidine in Patients in AML and CMML

To assess safety and tolerability at increasing dose levels of IO-202 as monotherapy and in combination with Azacitidine in successive cohorts of participants with relapsed or refractory AML with monocytic differentiation and CMML in order to estimate the maximum tolerated dose (MTD) or maximum administered dose (MAD) and select the …

tacrolimus
cyclosporine
azacitidine
remission
induction chemotherapy
  • 0 views
  • 16 May, 2022
  • 9 locations
Study Evaluating Safety and Efficacy of JCAR017 in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL)

This is a Phase 1/2, open-label, multicenter study to determine the efficacy and safety of JCAR017 in adult subjects with relapsed or refractory CLL or SLL. The study will include a Phase 1 part to determine the recommended dose of JCAR017 monotherapy in subjects with relapsed or refractory CLL or …

chronic lymphocytic leukemia
lymphoma
remission
chronic lymphocytic leukemia refractory
neutrophil count
  • 59 views
  • 09 Jul, 2022
  • 32 locations
Reduced-Intensity Conditioning for the Prevention of Treatment-Related Mortality in Patients Who Undergo a Hematopoietic Stem Cell Transplant

This phase II clinical trial evaluates whether a modified modality of conditioning reduces treatment-related mortality (TRM) in patients who undergo a hematopoietic stem cell transplant (HSCT) for a hematological malignancy. HSCT is a curative therapy for many hematopoietic malignancies, however this regimen results in higher rates of TRM than other …

ejection fraction
donor lymphocyte infusion
anemia
multiple myeloma
myeloid leukemia
  • 0 views
  • 08 Apr, 2022
  • 1 location
  • 0 views
  • 08 Jul, 2022
  • 5 locations
First-in Human (FIH) Trial of ETH-155008 in Subjects With B-NHL, CLL/SLL and AML

This Trial is a FIH, open-label, multicenter trial to evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of ETH-155008 in subjects with R/R B-cell NHL, CLL/SLL and AML who previously received standard treatment or are ineligible for standard treatment options.

hydroxyurea
neutrophil count
monoclonal antibody therapy
cell transplantation
tositumomab
  • 1 views
  • 20 Jun, 2022
  • 5 locations
HCL Single Arm Pilot Study in Treatment of Hyperglycemia of Pediatric ALL

lymphoblastic leukemia, during the induction chemotherapy phase while they are exposed to steroids and asparaginase that cause hyperglycemia.

  • 0 views
  • 02 May, 2022
  • 1 location
Phase I Study of Inotuzumab With Augmented BFM Re-Induction for Patients With Relapsed/Refractory B-cell ALL (ALL-001)

-cell acute lymphoblastic leukemia (B-ALL). Two re-induction regimens will be tested (one without pegaspargase and one including pegaspargase) and participants will be followed for disease status

ejection fraction
philadelphia chromosome
prednisone pill
pegaspargase
inotuzumab
  • 0 views
  • 18 Jun, 2022
  • 4 locations