Leukemia Clinical Trials

A listing of Leukemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 610 clinical trials
Vyxeos Plus Gilteritinib in Relapsed or Refractory, FLT3-Mutated AML

This study combines vyxeos and gilteritinib in patients with relapsed or refractory FLT3-mutated acute myeloid leukemia. Vyxeos and gilteritinib will be given as induction therapy. Those

  • 04 Jul, 2022
  • 1 location
Cord Blood Transplant With OTS for the Treatment of HIV Positive Hematologic Cancers

This phase II trial studies the side effects of a cord blood transplant using OTS and to see how well it works in treating patients with human immunodeficiency virus (HIV) positive hematologic (blood) cancers. After a cord blood transplant, the immune cells, including white blood cells, can take a while …

serum bilirubin level
HIV Vaccine
total body irradiation
  • 30 Jun, 2022
  • 1 location
Comparison of Triple GVHD Prophylaxis Regimens for Nonmyeloablative or Reduced Intensity Conditioning Unrelated Mobilized Blood Cell Transplantation

This randomized phase II trial includes a blood stem cell transplant from an unrelated donor to treat blood cancer. The treatment also includes chemotherapy drugs, but in lower doses than conventional (standard) stem cell transplants. The researchers will compare two different drug combinations used to reduce the risk of a …

lymphocytic leukemia
chromosome abnormality
chronic lymphocytic leukemia
colony stimulating factor
stem cell transplantation
  • 05 Jun, 2022
  • 1 location
Study of a Triple Combination Therapy, DTRM-555, in Patients With R/R CLL or R/R Non-Hodgkin's Lymphomas

Targeted drug therapies have greatly improved outcomes for patients with relapsed or refractory (R/R) chronic lymphocytic leukemia (CLL) and non-Hodgkin's lymphoma. However, single drug

lymphocytic leukemia
richter's syndrome
diffuse large b-cell lymphoma
  • 15 May, 2022
  • 8 locations
Phase 1 Study of the Dual MDM2/MDMX Inhibitor ALRN-6924 in Pediatric Cancer

This research study is studying a novel drug called ALRN-6924 as a possible treatment for resistant (refractory) solid tumor, brain tumor, lymphoma or leukemia. The drugs involved in this

cns tumor
stem cell infusion
small molecule
monoclonal antibody therapy
cns neoplasm
  • 01 Jul, 2022
  • 3 locations
Study of XL114 in Subjects With Non-Hodgkin's Lymphoma

This is a Phase 1, non-randomized, open-label, dose-escalation and expansion study, evaluating the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary clinical antitumor activity of XL114 administered alone orally to subjects with Non-Hodgkin's Lymphoma (NHL). The objectives of the study also include determining the recommended dose (RD) and/or maximum tolerated …

  • 02 May, 2022
Biology and Benefits of Music Play and Stories for Kids/Parents During ALL Treatment

of Acute Lymphoblastic Leukemia (ALL) treatment. Specific aims are to: Aim 1. Establish whether AME lowers child and parent cortisol during ALL treatment. Aim 2. Examine cortisol as a mediator of

  • 24 May, 2022
  • 1 location
Patient Centered Intervention to Prevent Tuberculosis Among Children Under Five Years Old

Isoniazid preventive therapy (IPT) reduces the risk of tuberculosis in 60%. Young children are at higher risk of developing severe forms of TB, though this can be prevented with a full course of IPT. Preliminary data indicate that 60% of eligible children start IPT, and 30% complete it. Furthermore, children …

  • 04 Jun, 2022
  • 1 location
Safety and Dose Finding Study of Neratinib in Children and Young Adults With Cancer That Has Returned or Not Responded to Treatment

The purpose of this study is to test the safety of neratinib at different dose levels and to find out what effects, good and bad, it has on the patients and the cancer.

human chorionic gonadotropin
solid tumor
cns tumor
ejection fraction
  • 09 Apr, 2022
  • 8 locations
A Trial of TTI-622 in Patients With Advanced Hematologic Malignancies (TTI-622-01)

Multicenter, open-label, phase 1a/1b Dose Escalation and Expansion Trial of TTI-622 in subjects with Advanced Hematologic Malignancies, Including Lymphoma, Leukemia, and Multiple Myeloma.

refractory multiple myeloma
  • 08 Jun, 2022
  • 13 locations