Leukemia Clinical Trials

A listing of Leukemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 87 clinical trials
A Trial of Epigenetic Priming in Patients With Newly Diagnosed Acute Myeloid Leukemia

The overall aim of this study is to determine if epigenetic priming with a DNA methyltransferase inhibitor (DMTi) prior to chemotherapy blocks is tolerable and carries evidence of a clinical efficacy signal as determined by minimal residual disease (MRD), event-free survival (EFS), and overall survival (OS). Tolerability for each of …

residual tumor
decitabine
hydroxyurea
sorafenib
daunorubicin
  • 41 views
  • 11 Aug, 2022
  • 12 locations
Bright Ideas - CIN Feasibility Study

In this study investigators will determine the feasibility of a future trial comparing chemotherapy-induced nausea control in children with ALL receiving oral 6-mercaptopurine who do and do not receive problem-solving skill training. This is a novel approach to controlling an important and common treatment-related symptom.

  • 0 views
  • 12 Aug, 2022
  • 2 locations
A Study of MBG453 in Combination With Azacitidine and Venetoclax in AML Patients Unfit for Chemotherapy (STIMULUS-AML1)

This trial will seek to extend the preliminary findings of efficacy of MBG453 in combination with hypomethylating agents (HMA) by evaluating MBG453 in combination with the HMA azacitidine and the Bcl-2 inhibitor venetoclax.

cell transplantation
venetoclax
azacitidine
  • 10 views
  • 11 Aug, 2022
  • 1 location
Pharmacokinetics, Safety, and Efficacy of ASTX727 in Combination With Venetoclax in Acute Myeloid Leukemia (AML)

when given in combination with venetoclax for the treatment of newly diagnosed acute myeloid leukemia (AML) in adults who are age 75 years or older, or who have comorbidities that preclude use of

venetoclax
decitabine
induction chemotherapy
ejection fraction
carbon monoxide
  • 0 views
  • 08 Aug, 2022
  • 16 locations
The Efficiency of CAMS (Chinese Academy of Medical Sciences)-2016 Trial for Pediatric Acute Myeloid Leukemia

The purpose of this study is to evaluate that whether the AML (acute myeloid leukemia)-CAMS (Chinese Academy of Medical Sciences)-2016 regimen, includes risk-stratified therapy and the use of

remission
consolidation therapy
  • 26 views
  • 09 Aug, 2022
  • 1 location
Study Evaluating the Safety of KITE-222 in Participants With Relapsed/Refractory Acute Myeloid Leukemia

(r/r) acute myeloid leukemia (AML).

fludarabine
refractory acute myeloid leukemia (aml)
secondary acute myeloid leukemia
gilbert's syndrome
ejection fraction
  • 0 views
  • 10 Aug, 2022
  • 7 locations
Study to Assess Adverse Events and Change in Disease State of Oral Venetoclax in Combination With Subcutaneous (SC) Azacitidine in Newly Diagnosed Adult Participants With Acute Myeloid Leukemia (AML) Who Are Ineligible for Intensive Chemotherapy in China

Acute myeloid leukemia (AML) is one of the most aggressive blood cancers, with a very low survival rate and few options for participants who are unable to undergo intensive chemotherapy, the

azacitidine
ejection fraction
venetoclax
carbon monoxide
  • 0 views
  • 09 Aug, 2022
  • 16 locations
Oral Decitabine-Based Maintenance Therapy in Patients With AML in Remission

acute myeloid leukemia that is under control (remission). Chemotherapy drugs, such as decitabine, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them

residual tumor
enasidenib
decitabine
cytarabine
consolidation therapy
  • 0 views
  • 19 Aug, 2022
  • 1 location
  • 0 views
  • 10 Aug, 2022
  • 6 locations
Study of CD19-directed Allogeneic Memory T-cell Therapy for Relapsed/Refractory CD19+ Leukemia

(CD19-CAR.CD45RA- negative T-cells) for the treatment of patients ≤ 21 years old with relapsed and/ or refractory CD19-positive leukemia. Primary Objective To determine the maximum

  • 0 views
  • 11 Aug, 2022
  • 1 location