Leukemia Clinical Trials

A listing of Leukemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 704 clinical trials
Fludarabine and Cytarabine Versus High-dose Cytarabine for CBF-AML

factor acute myeloid leukemia

hydroxyurea
neoadjuvant therapy
remission
fludarabine
cytarabine
  • 41 views
  • 29 May, 2022
  • 1 location
Cardioprotection in AML (AML 001)

Patients with acute myeloid leukemia (AML) often receive a drug called daunorubicin. Daunorubicin is a type of drug called an anthracycline, which increases the risk of some damage to the heart

hydroxyurea
induction chemotherapy
daunorubicin
anthracyclines
gilbert's syndrome
  • 0 views
  • 23 Jul, 2022
  • 1 location
Study of CD19-directed Allogeneic Memory T-cell Therapy for Relapsed/Refractory CD19+ Leukemia

(CD19-CAR.CD45RA- negative T-cells) for the treatment of patients ≤ 21 years old with relapsed and/ or refractory CD19-positive leukemia. Primary Objective To determine the maximum

  • 0 views
  • 24 Jul, 2022
  • 1 location
Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

acute myeloid leukemia (AML) or acute leukemia of ambiguous lineage (ALAL) that has come back (relapsed) or did not respond to treatment (refractory). Primary Objective To

  • 0 views
  • 01 May, 2022
  • 1 location
Venetoclax in Combination With Decitabine and Cedazuridine for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

This phase II trial studies the effects of venetoxlax in combination with decitabine and cedazuridine in treating patients with acute myeloid leukemia that has come back (relapsed) or does not

  • 0 views
  • 28 Jul, 2022
  • 1 location
A Pediatric and Young Adult Trial of Genetically Modified T Cells Directed Against CD22 for Relapsed/Refractory Leukemia or Lymphoma

Patients with relapsed or refractory leukemia or lymphoma are often refractory to further chemotherapy. In this study, the investigators will attempt to use T cells obtained directly from the

hydroxyurea
chemotherapy regimen
lymphoma
refractory leukemia
intrathecal chemotherapy
  • 0 views
  • 21 Apr, 2022
  • 4 locations
A Feasibility and Safety Study of Dual Specificity CD19 and CD22 CAR-T Cell Immunotherapy for CD19+CD22+ Leukemia

Patients with relapsed or refractory leukemia often develop resistance to chemotherapy and some patients who relapse following CD19 directed therapy relapse with CD19 negative leukemia. For this

immunosuppressive agents
corticosteroids
chemotherapy regimen
blast cells
graft versus host disease
  • 72 views
  • 26 Apr, 2022
  • 5 locations
Study of Fosciclopirox in Patients With Relapsed/Refractory Acute Myeloid Leukemia

This will be an open-label, Phase 1B/2A, study to characterize the efficacy, safety, pharmacokinetics, and pharmacodynamics of fosciclopirox administered alone and in combination with cytarabine in patients with R/R AML with up to two cohorts studied to confirm the efficacy (or futility) of fosciclopirox on the endpoint of disease response. …

  • 0 views
  • 14 Jun, 2022
  • 2 locations
Talazoparib and Gemtuzumab Ozogamicin for the Treatment of CD33 Positive Relapsed or Refractory Acute Myeloid Leukemia

myeloid leukemia that has come back (relapsed) or does not respond to treatment (refractory). Talazoparib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth

  • 0 views
  • 11 Jul, 2022
  • 2 locations
A Pilot Study of Metformin Therapy in Patients With Relapsed Chronic Lymphocytic Leukemia (CLL) and Untreated CLL

Metformin is an antidiabetic drug which is an inexpensive and generally well tolerated medication. More recently metformin has been shown to act against carcinomas by two mechanisms: 1) an indirect, insulin-dependent mechanism which sensitizes tissues to insulin, inhibits hepatic gluconeogenesis, and stimulates uptake of glucose in muscle, thereby reducing fasting …

direct bilirubin
gilbert's syndrome
conjugated bilirubin
fludarabine
lymphoid leukemia
  • 18 views
  • 29 May, 2022
  • 1 location