Leukemia Clinical Trials

A listing of Leukemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 600 clinical trials
A Study of CAR-GPRC5D in Patients With Relapsed/Refractory Multiple Myeloma or Plasma Cell Leukemia

This study is a single-center, open, dose-escalation study to observe the safety and efficacy of different doses of CAR-GPRC5D in patients with R/R MM or plasma cell leukemia.

  • 0 views
  • 05 Jun, 2022
  • 1 location
Venetoclax and Ibrutinib in Treating Patients With High-Risk Chronic Lymphocytic Leukemia

This phase II trial studies how well venetoclax and ibrutinib work in treating patients with high-risk chronic lymphocytic leukemia. Drugs used in chemotherapy, such as venetoclax, work in

neutrophil count
cancer
lymphoma
platelet count
beta human chorionic gonadotrophin
  • 58 views
  • 29 May, 2022
  • 1 location
Bosutinib in Pediatric Patients With Newly Diagnosed Chronic Phase or Resistant/Intolerant Ph + Chronic Myeloid Leukemia

This is a Phase 1-2, multicenter, international, single-arm, open-label study designed to identify a recommended dose of bosutinib administered orally once daily in pediatric patients with newly diagnosed chronic phase Ph+ CML (ND CML) and pediatric patients with Ph+CML who have received at least one prior TKI therapy (R/I CML), …

ejection fraction
anagrelide
myeloid leukemia
chronic myeloid leukemia
bosutinib
  • 0 views
  • 30 Jun, 2022
  • 44 locations
A Study of LOXO-305 in Chinese Participants With Blood Cancer (Including Lymphoma and Chronic Leukemia)

A study of the safety, side effects, and effectiveness of LOXO-305 in Chinese adults with lymphoma or chronic leukemia who have already had standard of care treatment. Participation could last

renal function tests
cancer
tyrosine
lymphoma
mantle cell lymphoma
  • 0 views
  • 29 Jun, 2022
  • 22 locations
Blinatumomab Followed by High-dose Chemotherapy for Ph-negative Acute Lymphoblastic Leukemia (ALL) (Blina-CELL)

This is a phase II interventional trial to evaluate the efficacy of blinatumomab followed by high-dose chemotherapy in the first-line treatment for Ph-negative acute lymphoblastic leukemia (ALL

  • 0 views
  • 06 May, 2022
  • 2 locations
A Trial of Epigenetic Priming in Patients With Newly Diagnosed Acute Myeloid Leukemia

The overall aim of this study is to determine if epigenetic priming with a DNA methyltransferase inhibitor (DMTi) prior to chemotherapy blocks is tolerable and carries evidence of a clinical efficacy signal as determined by minimal residual disease (MRD), event-free survival (EFS), and overall survival (OS). Tolerability for each of …

cytarabine
myeloid leukemia
fludarabine
hydroxyurea
sorafenib
  • 41 views
  • 22 Apr, 2022
  • 12 locations
A Study to Investigate Fadraciclib (CYC065), in Subjects With Leukemia or Myelodysplastic Syndrome (MDS)

and Phase 2 components in subjects with Leukemia or Myelodysplastic syndrome (MDS) who have progressed despite having standard therapy or for which no standard therapy exists.

ara-c
hydroxyurea
leukemia
decitabine
aml/mds
  • 0 views
  • 24 Apr, 2022
  • 2 locations
Fractionated Gemtuzumab Ozogamicin in Treating Measurable Residual Disease in Patients With Acute Myeloid Leukemia

This phase II trial studies the how well fractionated gemtuzumab ozogamicin works in treating measurable residual disease in patients with acute myeloid leukemia. Gemtuzumab ozogamicin is a

myeloid leukemia
flow cytometry
gemtuzumab
PCR test
residual tumor
  • 5 views
  • 19 Apr, 2022
  • 1 location
Trametinib in Treating Patients With Relapsed or Refractory Juvenile Myelomonocytic Leukemia

This phase II trial studies how well trametinib works in treating patients with juvenile myelomonocytic leukemia that has come back (relapsed) or does not respond to treatment (refractory

cytarabine
ejection fraction
bcr/abl
measurable disease
total serum bilirubin
  • 254 views
  • 19 Jun, 2022
  • 39 locations
Inotuzumab Ozogamicin and Chemotherapy in Treating Patients With Leukemia or Lymphoma Undergoing Stem Cell Transplantation

after a stem cell transplant. Researchers also want to learn if inotuzumab ozogamicin when given after a stem cell transplant can help control leukemia and lymphoma. Inotuzumab ozogamicin is a

ejection fraction
rituximab
methotrexate
b-cell acute lymphoblastic leukemia
inotuzumab
  • 2 views
  • 21 Apr, 2022
  • 1 location