Leukemia Clinical Trials

A listing of Leukemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 413 clinical trials
Cord Blood Transplant With OTS for the Treatment of HIV Positive Hematologic Cancers

This phase II trial studies the side effects of a cord blood transplant using OTS and to see how well it works in treating patients with human immunodeficiency virus (HIV) positive hematologic (blood) cancers. After a cord blood transplant, the immune cells, including white blood cells, can take a while …

blast crisis
pancytopenia
tumor cells
anemia
HIV Vaccine
  • 0 views
  • 02 May, 2022
  • 1 location
Study of a Triple Combination Therapy, DTRM-555, in Patients With R/R CLL or R/R Non-Hodgkin's Lymphomas

Targeted drug therapies have greatly improved outcomes for patients with relapsed or refractory (R/R) chronic lymphocytic leukemia (CLL) and non-Hodgkin's lymphoma. However, single drug

lymphoid leukemia
richter's syndrome
richter's transformation
leukemia
lymphoma
  • 7 views
  • 15 May, 2022
  • 8 locations
Comparison of Triple GVHD Prophylaxis Regimens for Nonmyeloablative or Reduced Intensity Conditioning Unrelated Mobilized Blood Cell Transplantation

This randomized phase II trial includes a blood stem cell transplant from an unrelated donor to treat blood cancer. The treatment also includes chemotherapy drugs, but in lower doses than conventional (standard) stem cell transplants. The researchers will compare two different drug combinations used to reduce the risk of a …

2-cda
lymphoid leukemia
ibrutinib
sirolimus
17p deletion
  • 64 views
  • 13 May, 2022
  • 1 location
Study of XL114 in Subjects With Non-Hodgkin's Lymphoma

This is a Phase 1, non-randomized, open-label, dose-escalation and expansion study, evaluating the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary clinical antitumor activity of XL114 administered alone orally to subjects with Non-Hodgkin's Lymphoma (NHL). The objectives of the study also include determining the recommended dose (RD) and/or maximum tolerated …

  • 0 views
  • 02 May, 2022
Safety and Dose Finding Study of Neratinib in Children and Young Adults With Cancer That Has Returned or Not Responded to Treatment

The purpose of this study is to test the safety of neratinib at different dose levels and to find out what effects, good and bad, it has on the patients and the cancer.

ejection fraction
cancer
human chorionic gonadotropin
lymphoma
solid tumour
  • 39 views
  • 09 Apr, 2022
  • 8 locations
A Trial of TTI-622 in Patients With Advanced Hematologic Malignancies (TTI-622-01)

Multicenter, open-label, phase 1a/1b Dose Escalation and Expansion Trial of TTI-622 in subjects with Advanced Hematologic Malignancies, Including Lymphoma, Leukemia, and Multiple Myeloma.

rituximab
venetoclax
multiple myeloma
dexamethasone
carfilzomib
  • 66 views
  • 27 Apr, 2022
  • 12 locations
Safety Study of Cord Blood Units for Stem Cell Transplants

Background Cord blood is blood that is taken from the umbilical cord and placenta of healthy newborns after childbirth. The cord blood collected from a baby is called a cord blood unit. Cord blood units are stored frozen in public cord blood banks. About 10,000 cord blood transplants have been …

cancer
hematologic malignancy
cell transplantation
  • 41 views
  • 18 May, 2022
  • 1 location
Ponatinib Plus Reduced-intensity Chemotherapy in the First-line Treatment of Adult Patients With Ph+ ALL (Pona-CELL)

leukemia. This combination has the potential to improve the depth of molecular responses after the induction phase of treatment. Patients who achieve a complete molecular response (CMR) at week 11 will not

  • 0 views
  • 29 Apr, 2022
  • 6 locations
Blinatumomab for Treatment of R/R or MRD-positive CD19-Positive MPAL

phenotypic acute leukemia (MPAL). Measurable Residual Disease (MRD) means that there are a small number of cancer cells remaining after treatment

  • 0 views
  • 14 May, 2022
  • 1 location
Testing the Use of Steroids and Tyrosine Kinase Inhibitors With Blinatumomab or Chemotherapy for Newly Diagnosed BCR-ABL-Positive Acute Lymphoblastic Leukemia in Adults

This phase III trial compares the effect of usual treatment of chemotherapy and steroids and a tyrosine kinase inhibitor (TKI) to the same treatment plus blinatumomab. Blinatumomab is a Bi-specific T-Cell Engager ('BiTE') that may interfere with the ability of cancer cells to grow and spread. The information gained from …

  • 14 views
  • 11 May, 2022
  • 49 locations