Leukemia Clinical Trials

A listing of Leukemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 413 clinical trials
In Vitro Expanded Allogeneic Epstein-Barr Virus Specific Cytotoxic T-Lymphocytes (EBV-CTLs) Genetically Targeted to the CD19 Antigen in B-cell Malignancies

relapsed B cell leukemia or lymphoma after a blood SCT organ SCT or for patients who are at high risk for relapse of their B cell leukemia or lymphoma.

cancer
cyclophosphamide
leukemia
lymphoma
flow cytometry
  • 41 views
  • 21 Apr, 2022
  • 1 location
Augmentation of the Graft vs. Leukemia Effect Via Checkpoint Blockade With Pembrolizumab

This is a single arm, open-label, Phase 1b study of pembrolizumab for patients with myelodysplastic syndrome (MDS), acute myeloid leukemia (AML), and acute lymphoblastic leukemia (ALL) whose

lymphoid leukemia
bone marrow procedure
cancer
leukemia
myeloid leukemia
  • 11 views
  • 23 Apr, 2022
  • 1 location
Cellular Immunotherapy in Treating Patients With High-Risk Acute Lymphoblastic Leukemia

This phase I trial studies the side effects and best dose of cellular immunotherapy in treating patients with high-risk acute lymphoblastic leukemia. Placing a modified gene into white blood

prednisone
corticosteroids
induction therapy
renal function
graft versus host disease
  • 1 views
  • 23 Apr, 2022
  • 1 location
CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies

Background B-cell leukemias and lymphomas are cancers that are often difficult to treat. The primary objective of this study is to determine the ability to take a

colony stimulating factor
bone marrow biopsy
graft versus host disease
immunosuppressive agents
lymphoma
  • 42 views
  • 10 May, 2022
  • 1 location
Fixed-duration Therapy With Ibrutinib and Obinutuzumab (GA-101) in Treatment-naïve Patients With CLL (FIGHT)

This is a phase 2 multicenter national interventional pharmacological study aimed at determining the efficacy of a fixed duration treatment with ibrutinib and obinutuzumab in terms of uMRD in the BM at the end of treatment (+30 Days follow-up). Treatment with ibrutinib and obinutuzumab will be administered according to the …

platelet count
obinutuzumab
lymphoma
neutrophil count
gilbert's syndrome
  • 0 views
  • 19 Apr, 2022
Efficacy of Acalabrutinib in Very Old or Frail Patients With Treatment-naïve or Relapsed/Refractory CLL (CLL-Frail)

The aim of this trial is to show the efficacy, safety and feasibility of acalabrutinib in a cohort of CLL-patients ≥80 years or with a FRAIL scale score >2 (5-item questionnaire to be filled out by the patient)

gilbert's syndrome
corticosteroids
acalabrutinib
platelet count
thrombocytopenia
  • 0 views
  • 09 Apr, 2022
  • 19 locations
A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia

This study will assess the safety, tolerability, pharmaokinetics, and preliminary efficacy of mosunetuzumab in participants with relapsed or refractory (R/R) chronic lymphocytic leukemia

chronic lymphocytic leukemia
cytopenia
  • 0 views
  • 03 May, 2022
  • 5 locations
Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL)

Chronic lymphocytic leukemia (CLL) is the most common leukemia (cancer of blood cells). The purpose of this study is to assess how well venetoclax + obinutuzumab (VenG) works and how safe they

chronic lymphocytic leukemia
venetoclax
cancer
remission
obinutuzumab
  • 0 views
  • 17 May, 2022
  • 2 locations
Efficacy of Venetoclax Based Regimen in Prevention Relapse of Consecutive MRD Positive AML Patients

Measurable disease (MRD) plays an important role in the therapeutic efficacy and prognosis of acute myeloid leukemia (AML). Studies show that persistent MRD positivity after induction indicates

  • 0 views
  • 12 May, 2022
  • 1 location
CAR-20/19-T Cells in Pediatric and Young Adult Patients With Relapsed/Refractory B Cell ALL (CAR-20/19-T)

This is a phase 1, interventional, open label, treatment study designed to evaluate the safety and feasibility of infusion of CAR-20/19-T in pediatric and young adult subjects with B cell ALL that have relapsed after prior therapies or refractory disease and are not candidates for curative intent standard therapy. There …

ejection fraction
serum bilirubin level
oximetry
blinatumomab
rituximab
  • 0 views
  • 22 Apr, 2022
  • 1 location