Leukemia Clinical Trials

A listing of Leukemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 413 clinical trials
A Safety Study of SEA-CD70 in Patients With Myeloid Malignancies

This trial will look at a drug called SEA-CD70 to find out if it is safe for patients with myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). It will study SEA-CD70 to find out

granulocyte colony stimulating factor
azacitidine
colony stimulating factor
residual tumor
lenalidomide
  • 38 views
  • 13 May, 2022
  • 14 locations
Fractionated Gemtuzumab Ozogamicin Followed by Non-engraftment Donor Leukocyte Infusions for Relapsed/Refractory Acute Myeloid Leukemia

This study includes patients with relapsed acute leukemia who have previously been treated with standard treatment that is still present and there is no curative treatment option available

remission
acute leukemia
fludarabine
leukapheresis
cancer
  • 3 views
  • 15 May, 2022
  • 1 location
Study of Azacitidine Combined With Homoharringtonie Based Regimens in AML

Rencent years have witnessed great progress of the treatment of acute myeloid leukemia. However, most patients have poor outcomes following the currently first-line DA(daunorubicin, cytarabine

cytarabine/daunorubicin
azacitidine
colony stimulating factor
cytarabine
idarubicin
  • 0 views
  • 15 May, 2022
  • 1 location
Phase I Dose Escalation Study of Intravenously Administered S64315 in Combination With Orally Administered Venetoclax in Patients With Acute Myeloid Leukaemia.

The purpose of this study is to determine the safety profile, tolerability and the Recommended Phase 2 Dose of the combination S64315 with venetoclax in patients with Acute Myeloid Leukaemia.

venetoclax
acute promyelocytic leukemia
serum bilirubin level
direct bilirubin
gilbert's syndrome
  • 31 views
  • 01 May, 2022
  • 4 locations
Efficacy and Pharmacogenomics of Salvage CLAG-M Chemotherapy in Patients With Relapse/Refractory and Secondary Acute Myeloid Leukemia

This is a prospective phase II clinical study to be conducted at the Medical College of Wisconsin. After meeting the study criteria and enrollment, patients will be treated with Cladribine, Cytarabine, Mitoxantrone, G-CSF (CLAG-M) chemotherapy and followed at periodic intervals to determine the primary and secondary objectives.

hemolysis
cladribine
colony stimulating factor
ejection fraction
mitoxantrone
  • 60 views
  • 01 May, 2022
  • 1 location
DC/AML Fusion Cell Vaccine vs Observation in Patients Who Achieve a Chemotherapy-induced Remission

This research study is studying a cancer vaccine called Dendritic Cell/AML Fusion vaccine (DC/AML vaccine) as a possible treatment for Acute Myelogenous Leukemia (AML). The interventions

venetoclax
cancer
residual tumor
blast cells
remission
  • 62 views
  • 02 May, 2022
  • 5 locations
A Clinical Trial to Evaluate Clifutinib in Patients With Relapsed or Refractory Acute Myeloid Leukemia(AML)

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of Clifutinib Besylate in Relapsed/refractory AML patients with FLT3-ITD mutation.

  • 0 views
  • 10 May, 2022
  • 1 location
  • 0 views
  • 05 May, 2022
  • 1 location
Goal Management Training for Adult Survivors of Childhood Acute Lymphoblastic Leukemia With Neurocognitive Sequelae

Survivors of childhood acute lymphoblastic leukemia (ALL) are at risk for developing neurocognitive sequelae. Multiple meta-analyses demonstrate significant deficits in overall intellectual

  • 0 views
  • 18 May, 2022
  • 3 locations
Venetoclax and CLAG-M for the Treatment of Acute Myeloid Leukemia and High-Grade Myeloid Neoplasms

patients with acute myeloid leukemia and high-grade myeloid neoplasms. Venetoclax may stop the growth of cancer cells by blocking Bcl-2, a protein needed for cancer cell survival. Chemotherapy drugs, such

granulocyte colony stimulating factor
cladribine
colony stimulating factor
ejection fraction
mitoxantrone
  • 0 views
  • 13 May, 2022
  • 1 location