Leukemia Clinical Trials

A listing of Leukemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 413 clinical trials
Study of Chidamide Combined With Cladribine in Refractory/Relapsed Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is highly heterogeneous, the efficacy of the individual varies greatly, and the risk of recurrence is high. A large number of newly diagnosed AML patients cannot

induction chemotherapy
cancer
cladribine
adult acute myelogenous leukemia
lymphoma
  • 0 views
  • 18 May, 2022
  • 1 location
Pharmacokinetic and Safety Study of MRX-2843 in Adolescents and Adults With Relapsed/Refractory AML, ALL, or MPAL

This is a Phase I, open-label, non-randomized, dose escalation study in adolescents and adults with relapsed/refractory acute myeloid leukemia, acute lymphoblastic leukemia, or mixed phenotype

  • 0 views
  • 26 Apr, 2022
  • 1 location
A Roll-over Study to Provide Continued Treatment With Lyophilized Pegaspargase (S95014) in Pediatric Patients With Acute Lymphoblastic Leukemia (ALL) (ALL)

The purpose of this study is to provide treatment with lyophilized S95014 in pediatric patients with ALL who completed the CL2-95014-002 study during the induction phase and who are clinically benefitting from S95014 without major toxicity.

  • 0 views
  • 12 May, 2022
  • 1 location
Effect of Metformin on ABCB1 and AMPK Expression in Adolescents With Newly Diagnosed Acute Lymphoblastic Leukemia

Acute lymphoblastic leukemia, is the most frequent cancer in children and adolescents. Some genes have been described to produce drug resistance, as ABCB1 probably by lack of activation of AMPK

  • 0 views
  • 06 May, 2022
  • 1 location
Calaspargase Pegol in Adults With ALL

Philadelphia-negative Acute Lymphoblastic Leukemia.

  • 0 views
  • 15 May, 2022
  • 8 locations
Early Clonal Dynamics During Venetoclax Treatment for Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL)

Background The drug venetoclax treats chronic lymphocytic leukemia (CLL). Researchers want to find better treatments for CLL. To do that, they need to learn how

night sweats
fatigue
thrombocytopenia
lymphadenopathy
lymphocytosis
  • 0 views
  • 09 May, 2022
  • 1 location
Chimeric Antigen Receptor T-cells for The Treatment of AML Expressing CLL-1 Antigen

Patients eligible for this study have a type of blood cancer Acute Myeloid Leukemia (AML) which has come back or has not gone away after treatment. The body has different ways of fighting

flow cytometry
blast cells
hematologic malignancy
lymphoma
cancer
  • 10 views
  • 23 Apr, 2022
  • 1 location
Study of Quizartinib in Combination With Standard Therapies in Chinese Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)

20 mg or 40 mg of quizartinib will be given to Chinese patients who were just diagnosed with AML. The study drug will be given to them along with standard therapies. The purpose is to find out the highest dose they can stand.

cytarabine
  • 8 views
  • 25 Apr, 2022
  • 1 location
Pharmacokinetics, Safety, and Efficacy of ASTX727 in Combination With Venetoclax in Acute Myeloid Leukemia (AML)

when given in combination with venetoclax for the treatment of newly diagnosed acute myeloid leukemia (AML) in adults who are age 75 years or older, or who have comorbidities that preclude use of

induction chemotherapy
ejection fraction
decitabine
carbon monoxide
venetoclax
  • 0 views
  • 28 Apr, 2022
  • 10 locations
Lintuzumab-Ac225 in Combination With Cladribine + Cytarabine + Filgastrim + Mitoxantrone (CLAG-M) for Relapsed/Refractory Acute Myeloid Leukemia

chemotherapy in the management of relapsed/refractory acute myeloid leukemia. This study uses a 3+3 design with a five-patient cohort at the recommended phase 2 dose.

ejection fraction
cladribine
secondary acute myeloid leukemia
blast cells
colony stimulating factor
  • 14 views
  • 05 May, 2022
  • 1 location