Immune Thrombocytopenia (ITP) Clinical Trials

A listing of Immune Thrombocytopenia (ITP) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 48 clinical trials
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A Study of PRN1008 in Adult Patients With Immune Thrombocytopenia (ITP)

This is a 2 part (Part A and B) adaptive, open-label, dose-finding study of PRN1008 in patients with ITP who are refractory or relapsed with no available and approved therapeutic options, with a platelet count <30,000/L on two counts no sooner than 7 days apart in the 15 days before …

thrombocytopenia
autoimmune thrombocytopenia
platelet count
  • 450 views
  • 23 Jul, 2021
  • 64 locations
None
Study to Evaluate Rilzabrutinib in Adults and Adolescents With Persistent or Chronic Immune Thrombocytopenia (ITP)

This is a randomized, double-blind study of rilzabrutinib in patients with persistent or chronic ITP, with an average platelet count of <30,000/μL (and no single platelet count >35,000/μL) on two counts at least 5 days apart in the 14 days before treatment begins. Patients will receive rilzabrutinib or placebo 400mg …

thrombocytopenia
igiv
platelet count
neutrophil count
kidney function tests
  • 30 views
  • 17 Dec, 2021
  • 84 locations
None
A Study of PRN1008 in Adult Patients With Immune Thrombocytopenia (ITP)

This is a 2 part (Part A and B) adaptive, open-label, dose-finding study of PRN1008 in patients with ITP who are refractory or relapsed with no available and approved therapeutic options, with a platelet count <30,000/μL on two counts no sooner than 7 days apart in the 15 days before …

thrombocytopenia
platelet count
  • 14 views
  • 05 Nov, 2021
  • 28 locations
None
Study to Evaluate Rilzabrutinib in Adults and Adolescents With Persistent or Chronic Immune Thrombocytopenia (ITP)

This is a randomized, double-blind study of rilzabrutinib in patients with persistent or chronic ITP, with an average platelet count of <30,000/μL (and no single platelet count >35,000/μL) on two counts at least 5 days apart in the 14 days before treatment begins. Patients will receive rilzabrutinib or placebo 400mg …

kidney function tests
thrombocytopenia
igiv
neutrophil count
platelet count
  • 5 views
  • 17 Dec, 2021
  • 87 locations
None
Avatrombopag for the Treatment of Thrombocytopenia in Pediatric Subjects With Immune Thrombocytopenia for 6 Months

A Phase 3b Study to Evaluate the Efficacy and Safety of Avatrombopag for the Treatment of Thrombocytopenia in Pediatric Subjects with Immune Thrombocytopenia for 6 Months

thrombocytopenia
avatrombopag
  • 13 views
  • 03 Nov, 2021
  • 50 locations
None
A First in HumanTrial to Evaluate The Safety Tolerability And Pharmacokinetics Of PF-06755347

This phase 1 single ascending dose study will provide a first in human assessment of safety and tolerability of PF-06755347 in healthy adult male subjects. The pharmacokinetics and pharmacodynamics will also be evaluated.

heart failure
administered intravenously
malignancy
cancer
  • 204 views
  • 16 Jan, 2022
  • 6 locations
None
Eltrombopag vs Standard Front Line Management for Newly Diagnosed Immune Thrombocytopenia (ITP) in Children

This is an investigator initiated, multicenter, open label, randomized phase 3 study for subjects with newly diagnosed ITP from ages 1 to less than 18 years old.

autoimmune thrombocytopenia
immunoglobulins
thrombocytopenia
immune globulin
prednisone
  • 10 views
  • 06 Oct, 2021
  • 11 locations
None
The DART Study- Daratumumab Treatment in ITP

A multicenter clinical, open-label total dose-escalating phase II study with safety run-in to explore the clinical activity, total dosage, and safety of daratumumab in adult ITP patients who have not responded adequately or relapsed after corticosteroids and at least one second-line therapy including rituximab and/or TPO-RA.

steroid therapy
rituximab
platelet count
corticosteroids
  • 0 views
  • 08 Jan, 2022
  • 4 locations
None
The PROLONG Trial - Rituximab Maintenance Therapy in ITP

This study is a two phase study that aims to evaluate if low-dose Rituximab maintenance therapy may prolong the the effect of Rituximab in immune thrombocytopenia.

prednisolone
rituximab
autoimmune thrombocytopenia
dexamethasone
thrombocytopenia
  • 156 views
  • 26 Jan, 2021
  • 1 location
None
  • 0 views
  • 18 Feb, 2021
  • 1 location