Hypercholesterolemia Clinical Trials

A listing of Hypercholesterolemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 149 clinical trials
Statins in Reducing Events in the Elderly (STAREE) Heart Sub-study

The STAREE-HEART sub-study will examine the effect of statin treatment over a 3-year period compared with placebo on markers of cardiac ageing. This will include determining global longitudinal strain with transthoracic echocardiography, atrial fibrillation with home measures twice daily for two weeks and changes in biomarkers.

electrocardiogram
diagnostic procedure
fibrillation
heart study
12 lead ECG
  • 10 views
  • 26 Jan, 2021
  • 1 location
Advancing Cardiac Care Unit-based Rapid Assessment and Treatment of hypErcholesterolemia (ACCURATE)

ACCURATE will test the hypothesis that opportunistic genetic testing for Familial Hypercholesterolemia (FH) in patients admitted to hospital with an acute coronary syndrome will increase the

genetic analysis
lipid-lowering therapy
acute coronary syndrome
LDL Cholesterol
cholesterol level
  • 0 views
  • 23 Mar, 2022
  • 1 location
Left Ventricular Hypertrophy Reduction With Statins in Hypertensive Patients

Experimental studies have showed that statins reduce left ventricular hypertrophy. The main objective is to observe the reduction of left ventricular hypertrophy with statins in hypertensive patients. The hypothesis is that patients treated with statins will have a reduction of at least 10% compared with patients treated only with antihypertensive …

left ventricular hypertrophy
valsartan
  • 4 views
  • 07 Nov, 2020
  • 1 location
Evaluate the Efficacy and Safety of IBI306 in Subjects With Homozygous Familial Hypercholesterolemia

evaluate the tolerability and safety of multiple-dose repeated administration of IBI306 in the Chinese population with hypercholesterolemia, and to recommend the dose for the second phase. The main purpose

  • 0 views
  • 10 Jul, 2021
  • 1 location
A Research Study Looking at New Protein-based Tablets in Healthy Men - Oral Formulation II

In this study, the study drug 'NNC0385-0434' will be tested in 3 different tablet formulations. These formulations are being tested for the treatment of hypercholesterolemia (high cholesterol

Accepts healthy volunteers
  • 0 views
  • 11 Aug, 2022
  • 1 location
Genetic Testing and Motivational Counseling for FH (GENMOTIV-FH)

To date, there are highly effective lipid-lowering drugs, the combination of which makes it possible to achieve the target level of LDL-C in most patients with familial hypercholesterolemia (FH

evolocumab
genetic analysis
ezetimibe
lipid-lowering therapy
atorvastatin
  • 0 views
  • 09 Aug, 2022
  • 1 location
The Combined Portfolio Diet and Exercise Study (PortfolioEx)

The purpose of this study is to determine whether a dietary portfolio of cholesterol-lowering foods (viscous fibres, soy protein, plant sterols and nuts) further enhanced by increased levels of monounsaturated fatty acids (MUFA) and low glycemic index foods; together with a structured exercise program reduce the progression of carotid and …

soy protein
diabetes
cholesterol measurement
hdl cholesterol
psyllium
  • 221 views
  • 24 Feb, 2022
  • 1 location
Lipid Management in Renal Transplant Recipients Using Evolocumab.

Cardiovascular disease is the leading cause of mortality after renal transplantation, accounting for more than 30% of deaths. Elevated lipid levels (hyperlipidemia) are a frequent finding following transplantation and the immunosuppressive medications play a central role in the development or worsening of hyperlipidemia. In the general population, the correlation between …

evolocumab
crestor
pravastatin
diabetes
cholesterol measurement
  • 0 views
  • 22 Jul, 2022
  • 1 location
A First in Human Study of STT-5058, an Antibody That Binds ApoC3

A First in Human Study of STT-5058, an Antibody That Binds ApoC3, investigating single and multiple ascending intravenous doses and ascending subcutaneous doses of STT-5058 in otherwise healthy volunteers with elevated triglyceride levels

monoclonal antibody
fasting
  • 66 views
  • 08 Jul, 2022
  • 1 location
A Phase 1, First Time in Humans Study of NST-1024

A first time in man study of NST-1024

Accepts healthy volunteers
  • 0 views
  • 10 Mar, 2022
  • 1 location