Hypercholesterolemia Clinical Trials

A listing of Hypercholesterolemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 148 clinical trials
Evaluate the Efficacy and Safety of Evinacumab in Pediatric Patients With Homozygous Familial Hypercholesterolemia

The primary objective for Part A of the study is to assess the pharmacokinetics (PK) of evinacumab in pediatric patients with homozygous familial hypercholesterolemia (HoFH). The primary

  • 14 Jul, 2021
  • 11 locations
Efficacy and Safety of Lomitapide in Paediatric Patients With Homozygous Familial Hypercholesterolaemia (HoFH)

This is a single arm, open label, multi centre phase III study to evaluate the efficacy and long term safety of lomitapide in paediatric patients with HoFH receiving stable LLT (including LA, when applicable) comprising of the following phases: Screening Period (starting at Week 12, i.e. ≤12 weeks prior to …

  • 15 Dec, 2021
  • 12 locations
Cascade Genetic Testing of Familial Hypercholesterolemia

Familial hypercholesterolemia (FH) is a frequent genetic disorder (1/200) associated with an increased risk of early-onset myocardial infarction. To improve detection and treatment of patient

genetic analysis
genetic disorder
myocardial infarction
cardiovascular disease
  • 13 May, 2021
  • 1 location
Citrulline Efficacy to Improve Carbohydrate Metabolism Abnormalities in the Patient Treated With High Doses of Statin

Hypercholesterolemia is a major cardiovascular risk factor. Statins are the first-line drug treatment for hypercholesterolemia and have been shown to be effective in both primary and secondary

  • 10 Aug, 2021
  • 1 location
Effect of Diet Induced Ketosis on LDL Turnover Rates

have had extreme elevations of LDL that mimic familial hypercholesterolemia. These marked elevations of LDLc are unique to a ketogenic diet and far exceed the typical mild elevations seen in those

Accepts healthy volunteers
  • 17 Nov, 2021
  • 1 location
Sacha Inchi Oil Supplementation in 3Hs

The objective of this study is to evaluate the effect of Sacha Inchi Oil supplementation among the 3Hs patients.

  • 21 Jun, 2021
  • 1 location
Evaluation of Clinical Impact of Interruption VS Maintenance of AI in Patients With Locally Advanced/ Metastatic Low Grade Endometrial Stromal Sarcoma (LGESS)

The primary objective is to compare the progression-free survival (PFS) between aromatase inhibitors interruption and aromatase inhibitors maintenance strategies in patients with a locally advanced or metastatic Low Grade Endometrial Stromal Sarcoma (LGESS).

  • 11 Aug, 2021
  • 18 locations
Technology-Assisted Cholesterol Trial in Consumers (TACTiC)

The purpose of this AUS is to evaluate the extent to which participants can safely and effectively self-select, purchase, and use Crestor OTC 5 mg for a 6-month period according to the label.

  • 26 Dec, 2021
  • 1 location
Safety and Efficacy of IBI306 in Chinese Subjects With Non-familiar Hypercholesterolemia

hypercholesterolemia with very high or high cardiovascular risk. This study will see if IBI306 will reduce low density lipoprotein cholesterol (LDL-C) in Chinese people who are taking a certain type of lipid-lowering

monoclonal antibody
LDL Cholesterol
lipoprotein cholesterol
low density lipoprotein
  • 27 Jan, 2021
  • 1 location
Efficacy and Safety of SHR-1209 Combined With Lipid-lowering Agents in Patients With Hypercholesterolemia and Hyperlipidemia

To evaluate the efficacy, safety, pharmacokinetics and immunogenicity of SHR-1209 subcutaneous administration in patients with hypercholesterolemia and hyperlipidemia after lipid-lowering

  • 16 Jan, 2022
  • 1 location