Hypercholesterolemia Clinical Trials

A listing of Hypercholesterolemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 148 clinical trials
Decreasing Patient Anxiety During Revascularization of Chronic Total Coronary Occlusions Using Virtual Reality Glasses. (ReViCTO)

Percutaneous coronary angioplasty on chronic total occlusions is a complex procedure. The possibility of performing these procedures without anesthesia and sedation avoids the risks associated with anesthesia and sedation, but, on the contrary, subjects the patient to pain and anxiety during the procedure. Virtual reality (VR) has been successfully used …

  • 25 Jul, 2022
  • 1 location
Moderately Carbohydrate-restricted Diet to Treat NAFLD in Adolescents

This will be a 6-month randomized clinical trial with two arms: moderately carbohydrate-restricted diet and a fat-restricted control diet. This 6-month study will have 2 phases: a 12-week controlled feeding phase and a 12-week "free living" phase. During the controlled feeding phase, all food will be provided to the families …

hemoglobin a1c
insulin resistance
a 12
  • 26 May, 2022
  • 1 location
Effect of PCSK9 Inhibition on Cardiovascular Risk in Treated HIV Infection (EPIC-HIV Study) (EPIC-HIV)

Atherosclerosis in the setting of HIV infection is distinct and includes increased vascular inflammation, worsened endothelial function, and a predominance of non-calcified plaque. These outcomes can be assessed using specialized noninvasive imaging which strongly predict future CV events in the general population. PCSK9 has emerged as an important pharmacologic target …

HIV Vaccine
myocardial infarction
type 2 diabetes mellitus
hiv-1 rna measurement
  • 09 May, 2022
  • 1 location
Lokelma for RAAS Maximisation in CKD & Heart Failure. (LIFT)

Background: CKD in patients with heart failure (HF) is common and associated with poor prognosis. Despite evidence of benefit with Renin-Angiotensin-Aldosterone-System inhibitor (RAASi) agents, they are avoided due to fear of hyperkalaemia. New potassium binders, e.g. Sodium Zirconium Cyclosilicate (SZC), reduce incidence of hyperkalaemia in CKD-HF patients and hence may …

heart failure
  • 14 Mar, 2022
ABM/P-15 Bone Graft vs Traditional Bone Graft in Adult Spinal Deformity Surgery

The purpose of this prospective trial is to investigate ABM/P-15 bone graft versus traditional bone graft in patients undergoing surgery for Adult Spinal Deformity (ASD) in order to provide better clinical results through faster bone healing, no additional surgeries, fewer complications and thereby increase health-related quality of life. Main hypotheses: …

  • 22 Mar, 2022
A Study to Evaluate the Pharmacokinetic Interaction and Safety Between BR1018-1 and BR1018-2 in Healthy Adult Subjects

The purpose of this study is to evaluate the pharmacokinetic characteristics and compare the safety and tolerability after repeated separate or combined administrations of BR1018-1 and BR1018-2 in healthy adults.

body mass index
Accepts healthy volunteers
  • 25 Jul, 2022
  • 1 location
Russian Familial Hypercholesterolemia Registry (RuFH)

Cardiology Research and Production Center, including patient demographics, past medical history, family history of hypercholesterolemia, physical findings, current lipid-lowering therapies, blood tests

low density lipoprotein
genetic analysis
cholesterol level
  • 24 Jan, 2022
  • 1 location
EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)

Familial hypercholesterolaemia (FH) is a common genetic disorder resulting in marked elevations in low-density lipoprotein cholesterol (LDL-C). If untreated, lifelong exposure to elevated LDL-C

genetic disorder
low density lipoprotein
early identification
cardiovascular disease
  • 27 Feb, 2022
  • 1 location
The Spanish Familial Hypercholesterolaemia Cohort Study

SAFEHEART is a large, on-going registry study in molecularly defined patients with heterozygous FH treated in Spain.

Accepts healthy volunteers
  • 14 Nov, 2021
  • 1 location
HoFH the International Clinical Collaborators Registry

Homozygous familial hypercholesterolemia (HoFH), a rare inherited disorder caused by bi-allelic mutations in the LDL Receptor pathway, is characterized by extremely elevated levels of low

  • 25 Jun, 2021
  • 4 locations