Hypercholesterolemia Clinical Trials

A listing of Hypercholesterolemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 14 clinical trials
Adjuvant Treatment in Elderly Patients With Periodontitis Through the Administration of a Supplement Rich in Oleuropein From the Olive Leaf (OLIVAGING)

Life expectancy has dramatically increased in the last century, although this process has not been always accompanied by an equivalent increase in healthy life expectancy. However, extending longevity without decreasing the risk of age-associated pathologies would not be desirable since non-communicable diseases can diminish seniors' quality of life, raise health-care …

periodontal treatment
chronic periodontitis
  • 0 views
  • 09 Aug, 2022
  • 1 location
  • 0 views
  • 20 Sep, 2022
  • 56 locations
Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Homozygous Familial Hypercholesterolemia (ORION-13)

This is a pivotal phase III study designed to evaluate safety, tolerability, and efficacy of inclisiran in adolescents with homozygous familial hypercholesterolemia (HoFH) and elevated low

  • 0 views
  • 09 Aug, 2022
  • 15 locations
  • 6 views
  • 18 Sep, 2022
  • 73 locations
Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial (CREST-2)

Carotid revascularization for primary prevention of stroke (CREST-2) is two independent multicenter, randomized controlled trials of carotid revascularization and intensive medical management versus medical management alone in patients with asymptomatic high-grade carotid stenosis. One trial will randomize patients in a 1:1 ratio to endarterectomy versus no endarterectomy and another will …

stroke
stenosis
transient ischemic attack
endarterectomy
angiography
  • 1155 views
  • 21 Sep, 2022
  • 135 locations
Effect of Serum LDL Cholesterol Concentration on Pancreatic Insulin Secretion

Dyslipidemia is characterized by low levels of HDLs, hypertriglyceridemia as well as an increases proportion of small dense LDLs. Changes in lipoprotein particles and its concentrations, especially increased levels of pro-atherogenic LDL particles play an important role in the development of cardiovascular diseases. It is well established that statin/PCSK9-inhibitor treatment …

hmg-coa reductase inhibitors
type 2 diabetes mellitus
cholesterol measurement
evolocumab
pcsk9
  • 84 views
  • 15 Sep, 2022
  • 1 location
  • 0 views
  • 20 Aug, 2022
Genetic Testing and Motivational Counseling for FH (GENMOTIV-FH)

To date, there are highly effective lipid-lowering drugs, the combination of which makes it possible to achieve the target level of LDL-C in most patients with familial hypercholesterolemia (FH

ezetimibe
atorvastatin
evolocumab
pcsk9
lipid-lowering therapy
  • 0 views
  • 09 Aug, 2022
  • 1 location
A Research Study Looking at New Protein-based Tablets in Healthy Men - Oral Formulation II

In this study, the study drug 'NNC0385-0434' will be tested in 3 different tablet formulations. These formulations are being tested for the treatment of hypercholesterolemia (high cholesterol

Accepts healthy volunteers
  • 0 views
  • 11 Aug, 2022
  • 1 location
Compassionate Use of Metreleptin in Previously-Treated Patients With Generalized Lipodystrophy

Background Generalized lipodystrophy can cause high blood fat levels and resistance to insulin. This can lead to health problems including diabetes. Researchers have found that the drug metreleptin improves health in people with this disease. Objective To test the safety and effectiveness of metreleptin. Eligibility People ages 6 months and …

insulin
glucose tolerance test
metreleptin
blood test
oral glucose tolerance test
  • 14 views
  • 20 Sep, 2022
  • 1 location