Hypercholesterolemia Clinical Trials

A listing of Hypercholesterolemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 10 clinical trials
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Safety of Lomitapide in Paediatric Patients With Homozygous Familial Hypercholesterolaemia (HoFH)

This is a single arm, open label, multi centre phase III study to evaluate the efficacy and long term safety of lomitapide in paediatric patients with HoFH receiving stable LLT (including LA, when applicable) comprising of the following phases: Screening Period (starting at Week 12, i.e. 12 weeks prior to …

  • 0 views
  • 26 Nov, 2021
  • 14 locations
None
Technology-Assisted Cholesterol Trial in Consumers (TACTiC)

The purpose of this AUS is to evaluate the extent to which participants can safely and effectively self-select, purchase, and use Crestor OTC 5 mg for a 6-month period according to the label.

  • 0 views
  • 03 Dec, 2021
  • 1 location
None
Study of Efficacy and Safety of Inclisiran in Asian Participants With Atherosclerotic Cardiovascular Disease (ASCVD) or ASCVD High Risk and Elevated Low Density Lipoprotein Cholesterol (LDL-C)

A multicenter study to evaluate safety and efficacy of inclisiran in Asian patients with ASCVD or ASCVD high risk and elevated LDL-C

serum low density lipoprotein
stroke
cardiovascular disease
ezetimibe
diabetes
  • 0 views
  • 05 Dec, 2021
  • 29 locations
None
Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial

Carotid revascularization for primary prevention of stroke (CREST-2) is two independent multicenter, randomized controlled trials of carotid revascularization and intensive medical management versus medical management alone in patients with asymptomatic high-grade carotid stenosis. One trial will randomize patients in a 1:1 ratio to endarterectomy versus no endarterectomy and another will …

stroke
stenosis
transient ischemic attack
endarterectomy
carotid revascularization
  • 1029 views
  • 29 Nov, 2021
  • 152 locations
None
Peer-delivered and Technology-Assisted Integrated Illness Management and Recovery

Adults with serious mental illness (SMI) are disproportionately affected by medical comorbidity, earlier onset of disease, and 10 to 25 years reduced life expectancy compared to the general population. These high rates of morbidity and early mortality are associated with inadequately managed medical and psychiatric illnesses. A recent systematic review …

Accepts healthy volunteers
psychiatric symptoms
  • 0 views
  • 23 Nov, 2021
  • 1 location
None
Ketogenic Diet Following Moderate to Severe Pediatric Traumatic Brain Injury

The primary objective of this study is to evaluate the feasibility and safety of using the ketogenic diet (KD) in children who sustained moderate to severe traumatic brain injury (TBI). The secondary objective is a preliminary evaluation of the outcomes of children who have had the standard of care plus …

amnesia
traumatic brain injury
coma
severe traumatic brain injury
  • 0 views
  • 05 Dec, 2021
  • 1 location
None
Effect of Probiotics in Non-alcoholic Fatty Liver Disease and Steatohepatitis

This study will evaluate the effect of probiotics, a beneficial intestinal bacteria supplement, if it will cause improvement of the non-alcoholic fatty liver disease (NAFLD) and or non-alcoholic steatohepatitis (NASH- an inflammation with concurrent fatty accumulation of the liver) as measured by transient elastography - an ultrasound of the liver …

fibroscan
elastography
liver disease
shear wave elastography
  • 0 views
  • 02 Dec, 2021
  • 1 location
None
Treatment With Bempedoic Acid and/or Its Fixed-dose Combination With Ezetimibe in Primary Hypercholesterolemia or Mixed Dyslipidemia

The primary objective is to describe in the real-world setting patient characteristics and outcomes of patients with primary hypercholesterolaemia (heterozygous familial and non-familial) or

stroke
cholesterol measurement
hypercholesterolemia
lipoprotein cholesterol
diabetes
  • 0 views
  • 05 Dec, 2021
  • 91 locations
None
Acute and Long-term Cardiovascular Toxicity After Modern Radiotherapy for Breast Cancer

whether these signs can predict later cardiovascular disease. The importance of traditional cardiovascular risk factors (age, hypertension, hypercholesterolemia, smoking habits and physical activity, as

coronary disease
cancer
heart failure
stroke
aromatase inhibitor
  • 0 views
  • 05 Dec, 2021
  • 4 locations
None
Plasma Hydrogen Sulfide as a Biomarker for Alzheimer's Disease and Related Dementias

Hydrogen sulfide is a signaling molecule that is important for vascular health. Because vascular factors such as hypertension and high cholesterol are risk factors for Alzheimer's disease and

dementia
depression
Accepts healthy volunteers
cognitive decline
alzheimer's disease
  • 0 views
  • 01 Dec, 2021
  • 1 location