Chronic Obstructive Pulmonary Disease (COPD) Clinical Trials

A listing of Chronic Obstructive Pulmonary Disease (COPD) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 403 clinical trials
Foster pMDI (CHF 1535) Versus Symbicort Turbohaler in COPD Patient

The purpose of the study is to demonstrate the non-inferiority of CHF1535 pMDI versus Symbicort Turbohaler in terms of lung function parameters and patients reported outcomes and to assess its safety and tolerability.

symbicort
bronchodilator
pulmonary function test
  • 0 views
  • 28 Jun, 2021
  • 53 locations
A Phase 3 Clinical Trial to Evaluate the Safety and Efficacy of Ensifentrine in Patients With COPD

The purpose of this study is to determine if ensifentrine is safe and effective for the treatment of patients with moderate to severe Chronic Obstructive Pulmonary Disease (COPD).

  • 152 views
  • 28 Nov, 2021
  • 92 locations
A Phase 3 Trial to Evaluate the Safety and Efficacy of Ensifentrine in Patients With COPD

The purpose of this study is to determine if ensifentrine is safe and effective for the treatment of patients with moderate to severe Chronic Obstructive Pulmonary Disease (COPD).

  • 427 views
  • 17 Dec, 2021
  • 146 locations
Tezepelumab COPD Exacerbation Study

Obstructive Pulmonary Disease (COPD)

bronchodilator
copd exacerbation
ct scan
severe chronic obstructive pulmonary disease
  • 175 views
  • 16 Jan, 2022
  • 83 locations
Pivotal Study to Assess the Efficacy, Safety and Tolerability of Dupilumab in Patients With Moderate to Severe COPD With Type 2 Inflammation

Primary Objective: To evaluate the efficacy of dupilumab administered every 2 weeks in patients with moderate or severe Chronic Obstructive Pulmonary Disease (COPD) as measured by

bronchodilator
pulmonary function test
severe chronic obstructive pulmonary disease
forced expiratory volume
cough
  • 184 views
  • 17 Jan, 2022
  • 468 locations
Mepolizumab as Add-on Treatment IN Participants With COPD Characterized by Frequent Exacerbations and Eosinophil Level (MATINEE)

This is a multi-center, randomized, placebo-controlled, double-blind, parallel group study designed to confirm the benefits of mepolizumab treatment on moderate or severe exacerbations in COPD participants given as an add on to their optimized maintenance COPD therapy. The maximum duration of participant participation is approximately 57 weeks, consisting of 2 …

albuterol
antibiotics
fluticasone
copd exacerbation
eosinophil count
  • 460 views
  • 07 Dec, 2021
  • 238 locations
Inhaled Long-acting Bronchodilators With or Without Inhaled Glucocorticosteroids for Preventing Hospitalizations and Death in Elderly Patients With Chronic Obstructive Pulmonary Disease

This will be a phase IV, open label, multicenter, randomized pragmatic study in frail elderly patients with COPD. Participants will be treated with either inhaled LABD alone or LABD combined with inhaled glucocorticosteroids. The main aim of the study is to assess whether, in elderly patients with COPD and one …

acute exacerbation of chronic obstructive pulmonary disease
bronchodilator
pulmonary function test
spirometry
cigarette smoke
  • 5 views
  • 15 Oct, 2021
  • 59 locations
A Phase 3 Adaptive Study to Evaluate the Safety and Efficacy of Inhaled Treprostinil in Participants With Pulmonary Hypertension (PH) Due to Chronic Obstructive Pulmonary Disease (COPD)

The primary objective of this study is to demonstrate the efficacy of inhaled treprostinil compared to placebo in improving exercise ability as measured by change from baseline in 6-Minute Walk Distance (6MWD) following 12 weeks of active treatment in participants with PH-COPD.

diuretics
vasodilator
left ventricular end-diastolic pressure
right heart catheterization
treprostinil
  • 2349 views
  • 16 Jan, 2022
  • 65 locations
Evaluation of the Safety and Efficacy of TLD in Patients With COPD

The purpose of this study is to confirm the safety and efficacy of the Nuvaira Lung Denervation System (Nuvaira System) in the treatment of COPD.

prednisone
bronchodilator
bronchoscopy
rehabilitation therapy
prednisolone
  • 318 views
  • 13 Aug, 2021
  • 35 locations
HFNC vs NPPV After Early Extubation for Patients With COPD

High-flow nasal cannula oxygen therapy(HFNC) has proved no significant difference compared with noninvasive positive pressure ventilation (NPPV) in preventing postextubation respiratory failure and reintubation in patients with acute hypoxemic respiratory failure.However, the efficacy of early postextubation sequential HFNC in COPD patients with hypercapnic respiratory failure is inconclusive.

nppv
bronchopulmonary infection
respiratory failure
pulmonary disease
noninvasive positive pressure ventilation
  • 3 views
  • 24 Jan, 2021
  • 1 location