Chronic Obstructive Pulmonary Disease (COPD) Clinical Trials

A listing of Chronic Obstructive Pulmonary Disease (COPD) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 367 clinical trials
A Phase III, Multicentre, Randomised, Double-blind, Chronic-dosing, Parallel-group, Placebo-controlled Study to Evaluate the Efficacy and Safety of Two Dose Regimens of Tozorakimab in Participants With Symptomatic Chronic Obstructive Pulmonary Disease (COPD) With a History of COPD Exacerbations (OBERON) (OBERON)

The purpose of this Phase III study is to evaluate the efficacy and safety of tozorakimab Dose 1 and Dose 2 administered subcutaneously (SC) in adult participants with symptomatic COPD and history of ≥ 2 moderate or ≥ 1 severe exacerbation of COPD in the previous 12 months. Participants should …

  • 0 views
  • 19 Aug, 2022
  • 90 locations
Pivotal Study to Assess the Efficacy, Safety and Tolerability of Dupilumab in Patients With Moderate to Severe COPD With Type 2 Inflammation (NOTUS)

Primary Objective: To evaluate the efficacy of dupilumab administered every 2 weeks in patients with moderate or severe Chronic Obstructive Pulmonary Disease (COPD) as measured by

muscarinic antagonists
bronchitis
forced expiratory volume
cough
copd exacerbation
  • 314 views
  • 02 Jul, 2022
  • 320 locations
Beta-blockers to Patients With Chronic Obstructive Pulmonary Disease

Background: In patients with chronic obstructive pulmonary disease (COPD) and concomitant cardiovascular conditions cardio-selective beta-blockers reduce mortality and can be used without

pulmonary function test
asthma
spirometry
bronchodilator
copd exacerbation
  • 37 views
  • 18 May, 2022
  • 1 location
A Phase II, Randomized, Double-blind, Placebo-controlled Study to Assess MEDI3506 in Participants With COPD and Chronic Bronchitis (FRONTIER-4)

This is a research study to determine the efficacy and safety of investigational drug MEDI3506 for the treatment of adult subjects with Chronic Obstructive Pulmonary Disease and Chronic Bronchitis.

pulmonary disease
spirometry
antibiotics
body mass index
cough
  • 96 views
  • 09 Aug, 2022
  • 91 locations
Evaluation of the Safety and Efficacy of TLD in Patients With COPD (AIRFLOW-3)

The purpose of this study is to confirm the safety and efficacy of the Nuvaira Lung Denervation System (Nuvaira System) in the treatment of COPD.

prednisolone
bronchodilator
pulmonary rehabilitation
bronchoscopy
prednisone
  • 435 views
  • 23 May, 2022
  • 33 locations
COPD and Socially Vulnerable Individuals

The trial investigates and describes the prevalence of COPD in patients who are in the social nurses' target group and investigates the effect of opportunistic screening for COPD in these vulnerable patients. The study population is patients who have been referred to a social nurse at hospitals in the Capital …

  • 0 views
  • 08 Sep, 2021
  • 11 locations
Mepolizumab as Add-on Treatment IN Participants With COPD Characterized by Frequent Exacerbations and Eosinophil Level (MATINEE)

chronic obstructive pulmonary disease (COPD) participants given as an add on to their optimized maintenance COPD therapy. The maximum duration of participant participation is approximately 109 weeks

muscarinic antagonists
antibiotics
fluticasone
cigarette smoke
copd exacerbation
  • 552 views
  • 23 Apr, 2022
  • 222 locations
Inhaled Long-acting Bronchodilators With or Without Inhaled Glucocorticosteroids for Preventing Hospitalizations and Death in Elderly Patients With Chronic Obstructive Pulmonary Disease

This will be a phase IV, open label, multicenter, randomized pragmatic study in frail elderly patients with COPD. Participants will be treated with either inhaled LABD alone or LABD combined with inhaled glucocorticosteroids. The main aim of the study is to assess whether, in elderly patients with COPD and one …

spirometry
bronchodilator
acute exacerbation of chronic obstructive pulmonary disease
cigarette smoke
heart failure
  • 5 views
  • 01 Feb, 2022
  • 35 locations
High-quality COPD Care for People With Immune Dysfunction Through Proactive E-consults

This study examines an intervention to promote effective, evidence-based care and de-implement inappropriate therapies for COPD in HIV-infected (HIV+) patients. The intervention facilitates specialist support of primary care, which includes infectious disease (ID) physicians who serve as the primary care providers (PCP) for their HIV+ patients in the ID clinic. …

  • 904 views
  • 26 Nov, 2021
  • 7 locations
Transitional Care Model Evaluation 2020

), chronic obstructive pulmonary disease (COPD), or pneumonia (PNA). The evaluation will be conducted by Mathematica.

pneumonia
copd exacerbation
heart failure
COPD
chronic obstructive pulmonary disease
  • 0 views
  • 25 Jan, 2021
  • 1 location