Chronic Obstructive Pulmonary Disease (COPD) Clinical Trials

A listing of Chronic Obstructive Pulmonary Disease (COPD) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 161 clinical trials
Phenotype Identification Based on Multimodal MRI Analysis of Patients With Bronchial Obstructive Diseases (PIMABOD)

The hypothesis is that pulmonary and cardiac proton MRI allows phenotyping of patients with bronchial obstruction by cluster analysis based on quantitative multimodal imaging of bronchi, pulmonary vessels, pulmonary parenchyma, right and left ventricular function, myocardial fibrosis and pulmonary arterial pressure. Such imaging will also offer the advantage of being …

  • 0 views
  • 04 Jun, 2022
  • 6 locations
Effect of AIRVO Heated Humidification in Bronchiectasis (AIRVO-BX)

The aim of the study is to investigate whether long-term heated humidification therapy (AIRVO) administrated for 1 year over-night on top of standard therapy can reduce the number of exacerbations in adults with non-cystic fibrosis bronchiectasis.

  • 43 views
  • 29 Jul, 2022
  • 14 locations
Study to Assess the Efficacy, Safety, and Tolerability of SAR440340/REGN3500/Itepekimab in Chronic Obstructive Pulmonary Disease (COPD) (AERIFY-1)

Primary Objective: Evaluate the efficacy of itepekimab compared with placebo on the annualized rate of acute moderate-or-severe COPD exacerbations in former smokers with moderate-to-severe COPD Secondary Objectives: Evaluate the efficacy of itepekimab compared with placebo on pulmonary function in former smokers with moderate-to-severe COPD Evaluate the efficacy of itepekimab compared …

  • 17 views
  • 26 Jul, 2022
  • 128 locations
Study to Assess the Efficacy, Safety, and Tolerability of SAR440340/REGN3500/Itepekimab in Chronic Obstructive Pulmonary Disease (COPD) (AERIFY-2)

Primary Objective: Primary population (former smokers cohort): Evaluate the efficacy of itepekimab compared with placebo on the annualized rate of acute moderate-or-severe COPD exacerbations in former smokers with moderate-to-severe COPD Secondary Objectives: Primary population (former smokers cohort): Evaluate the efficacy of itepekimab compared with placebo on pulmonary function in former …

  • 22 views
  • 25 Jul, 2022
  • 169 locations
Beta-blockers to Patients With Chronic Obstructive Pulmonary Disease

Background: In patients with chronic obstructive pulmonary disease (COPD) and concomitant cardiovascular conditions cardio-selective beta-blockers reduce mortality and can be used without

spirometry
copd exacerbation
respiratory symptom
pulmonary function test
bronchodilator
  • 21 views
  • 18 May, 2022
  • 1 location
Efficacy and Safety of Benralizumab in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With a History of Frequent Exacerbations (RESOLUTE)

Phase 3 study to evaluate the efficacy and safety of a benralizumab in patients with moderate to very severe COPD with a history of frequent COPD exacerbations and elevated peripheral blood eosinophils (≥300/μL). Eligible patients must have a history of ≥2 moderate and/or severe COPD exacerbations in the previous year …

antibiotics
corticosteroids
severe chronic obstructive pulmonary disease
bronchodilator
eosinophil count
  • 1757 views
  • 11 Jul, 2022
  • 291 locations
Pivotal Study to Assess the Efficacy, Safety and Tolerability of Dupilumab in Patients With Moderate to Severe COPD With Type 2 Inflammation (NOTUS)

Primary Objective: To evaluate the efficacy of dupilumab administered every 2 weeks in patients with moderate or severe Chronic Obstructive Pulmonary Disease (COPD) as measured by

severe chronic obstructive pulmonary disease
dyspnea
copd exacerbation
corticosteroids
bronchitis
  • 305 views
  • 02 Jul, 2022
  • 316 locations
Tezepelumab COPD Exacerbation Study (COURSE)

Obstructive Pulmonary Disease (COPD)

bronchodilator
ct scan
copd exacerbation
severe chronic obstructive pulmonary disease
  • 415 views
  • 23 Jul, 2022
  • 75 locations
Mepolizumab as Add-on Treatment IN Participants With COPD Characterized by Frequent Exacerbations and Eosinophil Level (MATINEE)

chronic obstructive pulmonary disease (COPD) participants given as an add on to their optimized maintenance COPD therapy. The maximum duration of participant participation is approximately 109 weeks

antibiotics
corticosteroids
copd exacerbation
fluticasone
eosinophil count
  • 551 views
  • 23 Apr, 2022
  • 222 locations
Evaluation of the Safety and Efficacy of TLD in Patients With COPD (AIRFLOW-3)

The purpose of this study is to confirm the safety and efficacy of the Nuvaira Lung Denervation System (Nuvaira System) in the treatment of COPD.

rehabilitation therapy
prednisone
bronchoscopy
bronchodilator
pulmonary rehabilitation
  • 426 views
  • 23 May, 2022
  • 33 locations