Chronic Obstructive Pulmonary Disease (COPD) Clinical Trials

A listing of Chronic Obstructive Pulmonary Disease (COPD) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 32 clinical trials
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Study of Effect of CSJ117 on Symptoms Pharmacodynamics and Safety in Patients With COPD

This is a Phase 2 study in patients with chronic obstructive pulmonary disease (COPD) to assess the efficacy, pharmacodynamics (PD), pharmacokinetics (PK), and safety of two dose levels of

  • 0 views
  • 02 Dec, 2021
  • 13 locations
None
RejuvenAir System Trial for COPD With Chronic Bronchitis

Chronic Obstructive Pulmonary Disease (COPD) is defined as an impaired ability to move air within the lungs and is a major public health problem that is projected to rank fifth worldwide in

pneumonia
pulmonary function tests
bronchodilator
obstruction
cough
  • 54 views
  • 29 Nov, 2021
  • 23 locations
None
Clinical Study to Assess the Mode of Action of QBW251 in Patients With Chronic Obstructive Pulmonary Disease (COPD)

The purpose of this study is to determine whether potentiating the cystic fibrosis transmembrane conductance regulator (CFTR) with QBW251 in subjects with COPD will be efficacious with regards to reducing lung and systemic inflammation and bacterial colonization as potential drivers of airway obstruction, airway destruction, remodeling and exacerbations. Furthermore, this …

airway obstruction
bronchodilator
cough
bronchitis
spirometry
  • 0 views
  • 01 Dec, 2021
  • 16 locations
None
A Phase 3 Trial to Evaluate the Safety and Efficacy of Ensifentrine in Patients With COPD

The purpose of this study is to determine if ensifentrine is safe and effective for the treatment of patients with moderate to severe Chronic Obstructive Pulmonary Disease (COPD).

  • 23 views
  • 29 Nov, 2021
  • 125 locations
None
A Phase 3 Clinical Trial to Evaluate the Safety and Efficacy of Ensifentrine in Patients With COPD

The purpose of this study is to determine if ensifentrine is safe and effective for the treatment of patients with moderate to severe Chronic Obstructive Pulmonary Disease (COPD).

  • 40 views
  • 28 Nov, 2021
  • 92 locations
None
Tezepelumab COPD Exacerbation Study

Obstructive Pulmonary Disease (COPD)

bronchodilator
copd exacerbation
severe chronic obstructive pulmonary disease
ct scan
  • 131 views
  • 30 Nov, 2021
  • 112 locations
None
Efficacy and Safety of Benralizumab in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With a History of Frequent Exacerbations

Phase 3 study to evaluate the efficacy and safety of a benralizumab in patients with moderate to very severe COPD with a history of frequent COPD exacerbations and elevated peripheral blood eosinophils (300/L). Eligible patients must have a history of 2 moderate and/or severe COPD exacerbations in the previous year …

corticosteroids
bronchodilator
eosinophil count
antibiotics
severe chronic obstructive pulmonary disease
  • 854 views
  • 02 Dec, 2021
  • 472 locations
None
Mepolizumab as Add-on Treatment IN Participants With COPD Characterized by Frequent Exacerbations and Eosinophil Level (MATINEE)

This is a multi-center, randomized, placebo-controlled, double-blind, parallel group study designed to confirm the benefits of mepolizumab treatment on moderate or severe exacerbations in COPD participants given as an add on to their optimized maintenance COPD therapy. The maximum duration of participant participation is approximately 57 weeks, consisting of 2 …

cigarette smoke
copd exacerbation
muscarinic antagonists
albuterol
corticosteroids
  • 400 views
  • 02 Dec, 2021
  • 238 locations
None
A Phase 3 Adaptive Study to Evaluate the Safety and Efficacy of Inhaled Treprostinil in Participants With Pulmonary Hypertension (PH) Due to Chronic Obstructive Pulmonary Disease (COPD)

The primary objective of this study is to demonstrate the efficacy of inhaled treprostinil compared to placebo in improving exercise ability as measured by change from baseline in 6-Minute Walk Distance (6MWD) following 12 weeks of active treatment in participants with PH-COPD.

diuretics
left ventricular end-diastolic pressure
vasodilator
right heart catheterization
treprostinil
  • 2043 views
  • 30 Nov, 2021
  • 70 locations
None
High-quality COPD Care for People With Immune Dysfunction Through Proactive E-consults

This study examines an intervention to promote effective, evidence-based care and de-implement inappropriate therapies for COPD in HIV-infected (HIV+) patients. The intervention facilitates specialist support of primary care, which includes infectious disease (ID) physicians who serve as the primary care providers (PCP) for their HIV+ patients in the ID clinic. …

  • 0 views
  • 26 Nov, 2021
  • 7 locations