Carcinoma Clinical Trials

A listing of Carcinoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 6203 clinical trials
Study to Evaluate the Efficacy and Safety of TT-00420 in Cholangiocarcinoma

This study is an open-label, multicenter study to evaluate the efficacy and safety of TT-00420 tablet in adult patients with advanced cholangiocarcinoma.

neutrophil count
measurable disease
  • 0 views
  • 13 Mar, 2022
  • 4 locations
A Study of Tislelizumab Combined With Radiotherapy as the Second-line Treatment of Advanced Biliary Malignant Tumors

Biliary tract cancer (BTC) accounts for 4% of the malignant tumors of the digestive system, and the incidence has increased significantly in recent years. For advanced malignant tumors of the biliary tract, the existing treatment methods are very limited and the effective rate is low. At present, gemcitabine combined with …

  • 0 views
  • 08 May, 2021
  • 1 location
Molecular Epidemiology of Biliary Tree Cancers

This study is to learn if certain risk factors (environmental, viral, behavioral, medical, and dietary), tumor markers, and genetic changes can predict the development and outcome of biliary tree cancers. Establishing biomarkers models from patients may help doctors to further understand how biliary tree cancer is affected by different treatments, …

cancer
  • 0 views
  • 17 Mar, 2022
  • 1 location
GEMOX Combined With Targeted Therapy and Immunotherapy for Patients With Advanced Cholangiocarcinoma

The clinical trial is designed to evaluate the safety and efficacy of GEMOX combined with targeted therapy and immunotherapy for patients with advanced cholangiocarcinoma, and screen the potential biomarkers

measurable disease
gemcitabine
metastasis
oxaliplatin
  • 0 views
  • 25 Mar, 2022
  • 1 location
RFA Combined With Chemotherapy for Unresectable Cholangiocarcinoma

Extrahepatic cholangiocarcinoma is a malignant tumor that is highly malignant and difficult to diagnose and treat early. Endobiliary radiofrequency ablation (RFA) has been reported to be a beneficial treatment option for palliation of malignant biliary strictures. Within the bile duct, RFA appears to be safe and may result in decreased …

chemotherapy drug
gemcitabine
  • 0 views
  • 06 Sep, 2021
  • 1 location
Phase 1 In-vivo Biliary Study of KSP/QRH Heptapeptide Dimer

The overall aim of this feasibility study is to develop new technologies for improved detection of cholangiocarcinoma using the SFE-based molecular-imaging mini-cholangioscope (MC) system. This study will combine the use of a fluorescent-labeled peptide dimer that binds specifically to know biomarkers of cholangiocarcinoma for use as a novel imaging agent …

EGFR
cancer
HER2
anticoagulants
  • 0 views
  • 22 Dec, 2021
  • 1 location
Chemo Alone or in Combination With Radiation in Unresectable Cholangiocarcinoma

The study evaluates impact of high dose radiation on overall survival in patients with unresectable nonmetastatic cholangiocarcinoma. The study randomizes patient between systemic chemotherapy alone and systemic chemotherapy and high dose radiation

non-resectable cholangiocellular carcinoma
gemcitabine
adenocarcinoma
metastasis
  • 14 views
  • 12 May, 2022
  • 1 location
Durvalumab and Tremelimumab With Platinum-based Chemotherapy in Intrahepatic Cholangiocarcinoma (ICC) (ICC)

This pilot trial will be used to assess the activity, safety and feasibility of doublet immunotherapy and platinum-based chemotherapy in resectable intrahepatic cholangiocarcinoma with high risk features. The hypothesis is that the combination of durvalumab/MEDI4736 and tremelimumab (doublet immunotherapy) with platinum-based chemotherapy (gemcitabine and cisplatin) will yield an objective of …

serum bilirubin
measurable disease
platelet count
cancer
gemcitabine
  • 0 views
  • 03 May, 2022
  • 1 location
Clinical Trial of Autologous Tcm Immunotherapy in ICC

The prime purpose of this trial is to evaluate the Progression Free survival and two-year survival of combining autologous Tcm cellular immunotherapy and traditional therapy in intrahepatic cholangiocarcinoma (ICC) patients after radical resection. A secondary objective of the trial is to assess the long-term survival and safety of Tcm cellular …

pulmonary disease
intrahepatic bile duct carcinoma
  • 7 views
  • 16 May, 2022
  • 1 location
TCF-001 TRACK (Target Rare Cancer Knowledge) Study

This open label, non-randomized, multi-center, pragmatic study aims to establish whether patients with rare tumors can benefit from matched molecular therapy as dictated by their next-generation sequencing (NGS) results.

cancer
  • 0 views
  • 21 Oct, 2021
  • 1 location