Breast Cancer Clinical Trials

A listing of Breast Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 2408 clinical trials
Study of Quality of Life Post Salpingo-oophorectomy in BRCA1/2 & PALB2 Mutation Carriers (BRCA-HRT) (BRCA-HRT)

Premenopausal BRCA1 / 2 or PALB2 gene mutation carriers who receive hormone replacement therapy (HRT) after preventive salpingo-oophorectomy (PBSO) have a better quality of sexual, psychological, cardiovascular and bone health than carriers who decline HRT. Premenopausal mutation carriers treated with PBSO who choose HRT have a comparable overall survival and …

  • 13 Jun, 2022
  • 1 location
Radiation-induced Cardiac Toxicity After Non-small Cell Lung Cancer Radiotherapy

Despite the growing interest in investigating how the radiotherapy (RT) dose to anatomical substructures of the heart links to survival, the heart substructures at risk remain poorly defined. They are not delineated routinely as part of the RT planning process and there is no consensus on their dose constrains. With …

stereotactic body radiation therapy
lung carcinoma
  • 02 Aug, 2021
  • 1 location
Cascade Genetic Testing for Hereditary Breast/Ovarian Cancer and Lynch Syndrome in Switzerland (CASCADE)

Breast, colorectal, ovarian, and endometrial cancers constitute approximately 30% of newly diagnosed cancer cases in Switzerland and affect more than 12,000 individuals annually. Several hundred of these patients are likely to carry known genetic mutations associated with HBOC or LS. Genetic testing for hereditary susceptibility to cancer can prevent many …

genetic testing
endometrial carcinoma
ovarian cancer
  • 05 Jun, 2022
  • 5 locations
Implementation of the Families Accelerating Cascade Testing Toolkit (FACTT) for Hereditary Breast and Ovarian Cancer and Lynch Syndrome

The purpose of this research study is to learn how cancer care providers can help their patients communicate the need for genetic testing in families with inherited cancer syndromes.

  • 15 Jun, 2022
  • 1 location
Embryo Health Study

This study intends to determine the patients' perception and motivation to obtain additional information on their preimplantation embryos' risks of polygenic disorders. Patients undergoing IVF and genetic testing on their embryos for aneuploidies will be given the option to obtain information of their embryos' polygenic disease risk after receiving genetic …

  • 17 Feb, 2021
  • 1 location
Clinical Value of MRD Monitoring for Adjuvant Therapy in Postoperative NSCLC

This clinical trial aims to explore the minimal residual disease (MRD) status of early NSCLC after curative surgery and the clinical outcomes of adjuvant chemotherapy. Next-generation sequencing technique will be used to examine the circulating tumor DNA (ctDNA) from MRD of 150 postoperative patients with stage IB-IIA NSCLC who received …

cancer chemotherapy
adjuvant chemotherapy
  • 01 Jan, 2022
  • 1 location
Exploring Compensation to Maintain Cognitive Function in Adults Newly Diagnosed With Brain Cancer

Recent research indicates that variability in cognitive function for brain tumor survivors may be explained by differences in cognitive reserve (CR) and use of compensatory strategies.However, it is unknown when cognitive function declines or survivors tap into compensation. This longitudinal mixed methods study proposes to explore differences in cognitive function …

  • 16 Aug, 2021
  • 1 location
Near-infrared Spectroscopy for Monitoring Tissue Oxygenation in Breast Reconstruction

The study will evaluate the use of near infrared spectrometry (NIRS)in detecting early microvascular complications in deep inferior epigastric artery perforator (DIEP)-flap(s).

breast reconstruction
near-infrared spectroscopy
bilateral breast reconstruction
  • 01 Feb, 2022
  • 1 location
Prospective Multicentre Study of the Use of Ketamine in the Treatment of Refractory Chronic Pain in the French CLCC

The primary objective of this study is to describe the administration practices of the antalgic Ketamine in French CLCC (Centre de Lutte Contre le Cancer) in terms of indication (neuropathic sequelae pains, morphine additional effect or morphine withdrawal, intensity, localisation) and administration protocol (route, posology, duration, administration sequence, premedication). The …

primary cancer
chronic pain
  • 17 Oct, 2021
  • 10 locations
The Role of Expectations on Complaints and Well-being After Endometriosis Surgery in Women

Endometriosis is a prevalent disease in women of procreative age. Most endometriosis patients are affected in their daily life by complaints such as chronic pelvic pain, dysmenorrhoea, infertility, or pain during sexual intercourse. Yet, its etiology is poorly understood. Although laparoscopy is well known as the gold standard for treating …

pelvic pain
endometriosis surgery
  • 26 Sep, 2021
  • 1 location