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Thymomas Clinical Trials

A listing of Thymomas medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (3) clinical trials

MK-3475 in Patients With Thymic Carcinoma

This is a phase II study of MK-3475 in thymic carcinoma patients after at least one prior chemotherapy regimen. Exploratory studies will be performed on archival tumor material (PDL-1 expression, next-generation sequencing) and fresh biopsies (culturing, next-generation sequencing). Simon's two-stage optimal design is used. The null hypothesis that the true ...


Study of Patients With Non-Small Cell Lung Cancer Esophageal Cancer Malignant Pleural Mesothelioma Mediastinal or Chest Wall Neoplasms or Lung Metastases From Cancers of Non-Thoracic Origin

OBJECTIVES: - Evaluate patients referred to the Thoracic Oncology Section of the Surgery Branch, NCI in order to identify patients who are suitable candidates for clinical research protocols. - Obtain biopsies during staging studies of tumor and adjacent normal tissues as well as serum and urine samples from patients with ...

Phase N/A

A Study of BKM120 (Buparlisib) in Relapsed or Refractory Thymomas

Thymic tumors are rare tumors, but represent the most common tumors of the anterior mediastinum. Thymoma has an indolent course in advanced disease and has the propensity to spread to the pleura. In first line therapy, combination chemotherapy produces responses in approximately 80% of patients. A number of single agents ...