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Atrial Fibrillation Clinical Trials

A listing of Atrial Fibrillation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (63) clinical trials

SmartTouch Catheter for Left Anterior Line - SmarT Line Study

Catheter ablation has emerged as a realistic therapeutic option for symptomatic atrial fibrillation (AF). The three main techniques described for ablation of persistent AF include pulmonary vein (PV) isolation, ablation based on electrogram analysis, and left atrial (LA) linear lesions. The ideal endpoint of linear lesions should be complete electrical ...


Antithrombotic Treatment in Patients With Effectively Maintained Sinus Rhythm After Atrial Fibrillation Ablation

The investigators hypothesize that the strategy of OAC will be superior to antiplatelet therapy, but low dose edoxaban (30mg) will be non-inferior to standard dose edoxaban (60mg) for reducing the risk of stroke or systemic embolism in patients who underwent successful AF ablation. Although AF ablation is an effective therapy ...


Randomized Trial Comparing Diltiazem and Metoprolol For Atrial Fibrillation Rate Control

If either an initial DT or MET strategy are shown to be more effective in obtaining rate and rhythm control, decreasing length of stay in the ED, and decreasing admissions and readmissions, there is a potential for: 1.) Major health cost savings; 2.) Improved bed utilization for our hospital, which ...


Detection of Silent Atrial Fibrillation aFter Ischemic StrOke

Atrial fibrillation (AF) is associated with a high risk of stroke and its prevalence increases in subjects aged 65 years. After an ischemic stroke, the use of standard monitoring methods may underestimate the detection rate of AF. Recent studies demonstrated a fourfold to sixfold increase in the detection of AF ...


ORal anticoaGulants in diAbetic and Nondiabetic Patients With nOn-valvular Atrial fibrillatioN (ORGANON)

Parameters evaluated: anthropometric indices glycated haemoglobin, basal and postprandial glycemia lipid profile small and dense LDL; oxidized LDL I troponin red and white cells count; platelets count creatinin, transaminases, iron fibrinogen, D-dimer, anti-thrombin III Hs-CRP, metalloproteinases 2 and 9 incidence of bleeding


Comparison of Efficacy and Safety Among Dabigatran Rivaroxaban and Apixaban in Non-Valvular Atrial Fibrillation

participants eligible participants are randomly assigned to dabigatran, rivaroxaban, or apixaban with allocation ratio of 1:1:1 Patients are randomly assigned to receive dabigatran (110 or 150 mg twice daily), rivaroxaban (15 or 20 mg daily), or apixaban (5 mg twice daily) with dosage and frequency approved by the Ministry of ...


Comparison Between Contact Force Guided and Blinded Strategy on PV Isolation in AF Patients

Sixty patients will be randomized to select right or left pulmonary veins whether to apply contact force-guided ablation or contact force-blinded ablation strategy. Each PV will be ablated with same contact force-sensing catheter (Thermocool Smart Touch Catheter, Biosense Webster Inc. CA). The PV (right or left) which will be randomized ...


AMIOdarone vs. Catheter Ablation for Prevention of Recurrent Symptomatic Atrial Fibrillation

This is a single centre vanguard phase prospective randomized open label study with blinded outcome adjudication. Patients will be randomized by a central randomization system (1:1) to amiodarone or catheter ablation. Amiodarone will be started at a dose of 400 mg/day. After one month the dose will be lowered to ...


Additional Linear Ablation Beyond Pulmonary Vein Isolation for Paroxysmal Atrial Fibrillation

Pulmonary vein(PV) isolation has become the cornerstone of radiofrequency ablation for AF. However, recent reports have clearly shown that the longer the follow-up period, the lower the success rate with a single ablation procedure. In 5-year follow-up, the mean success rate was only about 45%. The purpose of the study ...


Intensive Statin Therapy Effect on Post-Operative Atrial Fibrillation (POAF)

This is a randomized, double-blind comparison of two doses of atorvastatin for prevention of post-operative atrial fibrillation.