Diet and Nutrition Clinical Trials

A listing of Diet and Nutrition medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 283 clinical trials
Leukotriene A4 Hydrolase Stratified Trial of Adjunctive Corticosteroids for HIV-uninfected Adults With Tuberculous Meningitis

The primary objective is to determine whether Leukotriene A4 hydrolase (LTA4H) genotype, defined at randomisation, determines dexamethasone's clinical effectiveness when added to the first 6-8 weeks of anti-tuberculosis treatment of TBM. The investigators will conduct a LTA4H genotype stratified, parallel group, randomised, double blind, placebo-controlled multi-centre Phase III non-inferiority trial …

tuberculosis treatment
rifampin
corticosteroids
tb chemotherapy
isoniazid
  • 53 views
  • 28 Apr, 2022
  • 1 location
Study of Safety and Efficacy of DKY709 Alone or in Combination With PDR001 in Patients With Advanced Solid Tumors.

This is a phase I/Ib, open label study. The escalation portion will characterize the safety and tolerability of DKY709 and DKY709 in combination with PDR001 in subjects with NSCLC or melanoma who have received prior anti-PD-1/PD-L1 therapy, or subjects with NPC. After the determination of the MTD/RD for a particular …

solid tumour
cancer
core needle biopsy
programmed cell death 1 ligand 1
metastasis
  • 141 views
  • 06 Jun, 2022
  • 8 locations
First Line Atezolizumab, Paclitaxel, and Bevacizumab (Avastin®) in mTNBC (ATRACTIB)

This is a multicenter, open-label, single-arm, phase II clinical trial to evaluate to evaluate the efficacy and safety of first line atezolizumab in combination with paclitaxel and bevacizumab (Avastin®) in patients with advanced or metastatic triple-negative breast cancer (mTNBC)

  • 0 views
  • 19 Jun, 2022
  • 20 locations
First-in-human Study of DS-1062a for Advanced Solid Tumors (TROPION-PanTumor01)

This study is one single group of participants with non-small cell lung cancer (NSCLC) who have not been cured by other treatments. It is the first time the drug has been used in humans, and will be in two parts. The primary purpose of the parts are: Dose Escalation: To …

epidermal growth factor
targeted therapy
triple negative breast cancer
progesterone receptor
cancer
  • 280 views
  • 07 Jul, 2022
  • 14 locations
HiLo: Pragmatic Trial of Higher vs Lower Serum Phosphate Targets in Patients Undergoing Hemodialysis

increased serum albumin and protein catabolic rate (PCR), as markers of diet and nutrition. The 2nd objective of HiLo is to conduct a second-generation pragmatic clinical trial in dialysis. In

  • 0 views
  • 07 Jun, 2022
  • 5 locations
A First-in-Human Study of CAN04 in Patients With Solid Malignant Tumors (CANFOUR)

This study will evaluate the safety, tolerability, and preliminary antitumor activity of CAN04 both as a monotherapy and in combination with standard of care treatment in subjects with solid cancer tumors. Following completion of the first part, the dose escalation cohorts, and determination of maximum tolerated dose or recommended phase …

paclitaxel
cancer
pdac
ct scan
lung carcinoma
  • 244 views
  • 29 Jan, 2022
  • 20 locations
A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ABBV-927 With ABBV-368, Budigalimab (ABBV-181) and/or Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors

A study evaluating the safety, pharmacokinetics (PK), pharmacodynamics, and preliminary efficacy of ABBV-927 with ABBV-368, Budigalimab (ABBV-181) and/or chemotherapy in participants with selected solid tumors. This study consists of 2 main parts, a dose-escalation phase and a dose-expansion phase. The dose-expansion phase can begin once the recommended phase 2 dose/maximum …

adenocarcinoma
advanced malignant solid tumor
primary cancer
epidermal growth factor
progesterone receptor
  • 56 views
  • 26 Jul, 2022
  • 22 locations
New Heart Imaging Techniques to Evaluate Possible Heart Disease

Background Imaging tests, such as magnetic resonance imaging (MRI), can provide information about heart and blood vessels. The tests let doctors can see the amount of blood vessel narrowing and vessel wall thickness. This information may help diagnose and treat heart disease and other conditions that lead to heart attacks. …

diabetes mellitus
hyperlipidemia
ct scan
angiography
cardiovascular disease
  • 336 views
  • 26 Jul, 2022
  • 1 location
Prospective Biobanking Study in Ovarian, Breast and Head and Neck Cancer Patients Aiming at Better Understand the Link Between the Molecular Alterations of the Tumor Itself, Its Microenvironment and Immune Response (SCANDARE) (SCANDARE)

SCANDARE is a prospective biobanking study on tumor (+/- nodes), plasma and blood samples at different time points in ovarian, triple negative breast and head and neck cancer patients. This study will allowed to identify new molecular and/or immunological biomarkers associated with clinical and biological features of the tumors. All …

cancer
immunomodulator
triple-negative breast cancer
breast cancer
cancer chemotherapy
  • 3 views
  • 25 Mar, 2022
  • 2 locations
GEN1046 Safety Trial in Patients With Malignant Solid Tumors

The purpose of the trial is to evaluate the safety of GEN1046 as monotherapy and in combination therapies in patients with malignant solid tumors

stage iv non-small cell lung cancer
squamous cell carcinoma of head and neck
cancer
pembrolizumab
measurable disease
  • 93 views
  • 26 Mar, 2022
  • 41 locations