Diet and Nutrition Clinical Trials

A listing of Diet and Nutrition medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 145 clinical trials
FUSCC Refractory TNBC Umbrella (FUTURE) (FUTURE)

This is a Phase Ib/II, open-label, multi-center umbrella study evaluating the efficacy and safety of multiple targeted treatment in patients with refractory metastatic TNBC.The specific grouping of patients' depends on FUSCC 500+ gene panel testing and IHC subtype staining.

breast cancer
measurable disease
  • 18 Apr, 2022
  • 1 location
Cabiralizumab in Combination With Nivolumab and Neoadjuvant Chemotherapy in Patients With Localized Triple-negative Breast Cancer

The hypothesis of this study is that the combination of cabiralizumab and nivolumab with neoadjuvant chemotherapy will decrease tumor associated macrophages (TAMs) and increase tumor infiltrating lymphocytes (TIL) compared to neoadjuvant chemotherapy plus nivolumab in patients with early stage triple-negative breast cancer (TNBC) and improve clinical outcomes.

growth factor
her2/neu-negative breast cancer
  • 18 Apr, 2022
  • 1 location
The Efficacy of Cryotherapy in Pregnancy Related Pelvic Girdle Pain

The findings from this project may result in pain reduction and improved mobility in pregnant women with pelvic girdle pain in their second and third trimester.

  • 21 Apr, 2022
  • 1 location
Cardiovascular Health Arterial Stiffness Raspberry and Microbiome (CHARM) (CHARM)

In this study, the investigators aim to determine the health benefits of red raspberry ellagitannin consumption on cardiovascular health. The study population is stratified according to the urolithin metabotypes (gut-microbial metabolic profile): UM-0, UM-A and UM-B. The investigators will evaluate changes in blood pressure, endothelial function, arterial stiffness, lipid profile, …

Accepts healthy volunteers
  • 27 Apr, 2022
  • 1 location
Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BIIB107 in Healthy Adult Participants

The primary objective is to determine the safety and tolerability of single and multiple ascending subcutaneous (SC) doses and single ascending intravenous (IV) doses of BIIB107 in healthy adult participants. The secondary objectives are to characterize the single-dose pharmacokinetic (PK) of SC and IV BIIB107 in healthy adult participants and …

Accepts healthy volunteers
  • 28 Apr, 2022
  • 2 locations
Human Oral Detection of Glucose Olygomers

Although salivary contents play a major role in the early stage of food digestion process, their role in taste perception of glucose polymers is essentially unknown. It is hypothesized that the differences in salivary contents, more specifically salivary amylase concentration and activity, influence taste perception of glucose polymers and ultimately …

Accepts healthy volunteers
  • 04 May, 2022
  • 1 location
Tavo and Pembrolizumab With or Without Chemotherapy in Patients With Inoperable Locally Advanced or Metastatic TNBC

This is a Phase 2, Multi-Cohort, Open-Label, Multi-Center Study. Cohort 1 will be a single-arm study of intratumoral tavokinogene telseplasmid (tavo) plus electroporation (EP) in combination with pembrolizumab therapy. Cohort 2 will be a single-arm study of intratumoral tavo-EP plus pembrolizumab with nab-paclitaxel (Abraxane®) chemotherapy. Subjects with TNBC and EP …

epidermal growth factor receptor
epidermal growth factor
measurable disease
serum pregnancy test
  • 06 May, 2022
  • 12 locations
Establishing Functional Biomarkers for Spaced Theta-Burst Stimulation

The investigators plan to use functional magnetic resonance imaging (fMRI) methods to assess brain changes following spaced theta burst stimulation (TBS), a new form of repetitive transcranial magnetic stimulation (rTMS), in 10 healthy participants. The investigators will measure the effects of both excitatory (intermittent, iTBS) and inhibitory (continuous, cTBS) TBS …

Accepts healthy volunteers
  • 18 May, 2022
  • 1 location
Tracking Information Flow in the Brain (BRAINDYN)

The brain is composed of a set of areas specialized in specific computations whose outputs need to be transferred to other specialized areas for cognition to emerge. To account for context-dependent behaviors, the information must be flexibly routed through the fixed anatomy of the brain. The aim of this project …

Accepts healthy volunteers
  • 24 May, 2022
  • 1 location
A Pharmacokinetics and Tolerability Study of Fedratinib in Subjects With Moderate and Severe Hepatic Impairment

This is a Phase 1, multicenter, nonrandomized, open-label, single oral dose study to assess the PK of fedratinib in subjects with moderate and severe hepatic impairment, and in matched subjects with normal hepatic function. Degrees of hepatic impairment will be determined during screening by the subject's score according to Pugh's …

body mass index
moderate hepatic insufficiency
  • 17 Jun, 2022
  • 3 locations