Respiratory Failure Clinical Trials

A listing of Respiratory Failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 345 clinical trials
Featured trial
Double-Blind, Randomized, Placebo-Controlled, Multi-Center Phase 3 Study to Evaluate the Efficacy and Safety of Fostamatinib in COVID-19 Subjects

COVID-19 without respiratory failure and with certain high risk prognostic factors, as measured by the change in clinical status score.

covid-19
  • 2 views
  • 10 Dec, 2021
  • 35 locations
Featured trial
Longitudinal Observational Study of Severe Asthma

Background: Asthma is a lung condition that causes difficulty breathing and decreased lung function. Some people with asthma have more severe disease symptoms. They

asthmatic
allergic asthma
asthma
  • 30 views
  • 22 Dec, 2020
  • 1 location
Efficacy of DEXamethasone in Patients With Acute Hypoxemic REspiratory Failure Caused by INfEctions (DEXA-REFINE)

Background: There are no proven therapies specific for pulmonary dysfunction in patients with acute hypoxemic respiratory failure (AHRF) caused by infections (including Covid-19). The full

  • 0 views
  • 10 Apr, 2022
High Flow Nasal Cannula With Noninvasive Ventilation

This is a prospective, randomized, unblinded trial of trauma patients in the ICU who are identified as being at a high risk to develop acute respiratory failure. We hope that this study

  • 0 views
  • 26 Apr, 2022
  • 1 location
DirEct Versus VIdeo LaryngosCopE Trial (DEVICE)

Clinicians perform rapid sequence induction, laryngoscopy, and tracheal intubation for more than 5 million critically ill adults as a part of clinical care each year in the United States. Failure to intubate the trachea on the first attempt occurs in more than 10% of all tracheal intubation procedures performed in …

  • 6 views
  • 08 Jul, 2022
  • 9 locations
Randomized Trial of Sedative Choice for Intubation (RSI)

Among critically ill adults undergoing emergency tracheal intubation, one in five experience hypotension, cardiac arrest, or death. The sedatives used to rapidly induce anesthesia for emergency tracheal intubation have been hypothesized to effect cardiovascular complications and patient outcomes, but the optimal sedative medication for intubation of critically ill adults remains …

  • 0 views
  • 04 Oct, 2022
  • 1 location
Pragmatic Trial Examining Oxygenation Prior to Intubation (PREOXI)

Clinicians perform rapid sequence induction, laryngoscopy, and tracheal intubation for more than 5 million critically ill adults as a part of clinical care each year in the United States. One-in-ten emergency tracheal intubations is complicated by life-threatening hypoxemia. Administering supplemental oxygen prior to induction and intubation ("preoxygenation") decreases the risk …

  • 3 views
  • 04 Oct, 2022
  • 10 locations
Miller Blade for Intubation in Adults

The study compares laryngeal view obtained with standard Macintosh blade laryngoscope and Miller blade laryngoscope in adult patients. After introduction to general anesthesia anesthesiologist will perform laryngoscopy with one chosen blade and after evaluation of visualisation of entrance to larynx will change blade to second one and repeat evaluation.

  • 0 views
  • 04 Oct, 2022
  • 1 location
A Multicenter, Adaptive, Randomized Controlled Platform Trial of the Safety and Efficacy of Antithrombotic and Additional Strategies in Hospitalized Adults With COVID-19 (ACTIV-4A)

This is a randomized, open label, adaptive platform trial to compare the effectiveness of antithrombotic and additional strategies for prevention of adverse outcomes in COVID-19 positive inpatients

  • 287 views
  • 25 Oct, 2022
  • 100 locations
Speeding the Weaning up: Aggressive Screening Criteria and Higher Minimal Ventilatory Settings. (SPEED-UP)

Hypothesis In patients with less than 4 high risk factors for reintubation excluding body mass index >30 and hypercapnia during the spontaneous breathing trial (SBT) (low and intermediate risk for extubation failure), who receive preventive therapy with high flow nasal cannula (HFNC), the use of SBT with "HIGH minimal ventilator …

  • 0 views
  • 04 Oct, 2022
  • 1 location