Shingles Clinical Trials

A listing of Shingles medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 8 clinical trials
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Pilot Study of Reduced-Intensity Hematopoietic Stem Cell Transplant of DOCK8 Deficiency

Background -DOCK8 deficiency is a genetic disorder that affects the immune system and can lead to severe recurrent infections and possible death from infections or certain types of cancers, including blood cancers. A stem cell transplant is a life-saving treatment for this condition. In this study we are evaluating the …

Accepts healthy volunteers
  • 1 views
  • 24 Oct, 2021
  • 1 location
None
Recombinant Zoster Vaccine in Stable SLE Patients

reactivation limited the use of live-attenuated shingles vaccine in SLE patients, especially in whom with high dose of prednisone or immunosuppressants. Whether the introduction of recombinant zoster vaccine

belimumab
prednisone
lupus
mycophenolate
zoster vaccine
  • 0 views
  • 10 Oct, 2021
None
Stimulation of the Rostral Zona Incerta for Parkinson's Disease

the subthalamic nucleus (STN). The brain area just above the STN is called the rostral Zona Incerta (rZI). The rZI may be a potential target for deep brain stimulation, in combination with the STN.

brain stimulation
  • 5 views
  • 19 Oct, 2021
  • 1 location
None
Bendamustine/Rituximab Followed by Venetoclax and Rituximab for Treatment of Chronic Lymphocytic Leukemia

The purpose of this study is to determine the efficacy of bendamustine and rituximab (BR) followed by venetoclax for 12 months. The total time on therapy is 15 months. Bendamustine and rituximab is a commonly used treatment for CLL. Venetoclax is an oral drug that blocks a protein called BCL-2 …

lymphocytosis
thrombocytopenia
rituximab
platelet count
corticosteroids
  • 3 views
  • 14 Oct, 2021
None
T-Lymphocytes for Prevention or Treatment of Viral Infections Following Hematopoietic Stem Cell Transplantation

This Phase I dose-escalation trial is designed to evaluate the safety of rapidly generated multivirus-specific T-cell products with antiviral activity against CMV, EBV, adenovirus, HHV6, BK virus, JC virus, and human parainfluenza-3 (HPIV3), derived from eligible HSCT donors. In this trial, we will utilize a rapid generation protocol for broad …

prednisone
parainfluenza
cmv infection
stem cell transplantation
antiviral drugs
  • 54 views
  • 22 Oct, 2021
  • 1 location
None
Viral Infections in Healthy and Immunocompromised Hosts

Background Viral infections are an important cause of illness and death in hospitalized patients as well as outpatients. New strains of viruses may appear and infect both healthy people and those with weak immune systems. A better understanding of these new virus strains (such as SARS-CoV-2, the virus that causes …

immunoglobulin
Accepts healthy volunteers
  • 254 views
  • 21 Oct, 2021
  • 1 location
None
Prevention of Post Herpetic Neuralgia by Ultrasound Guided Single Nerve Block in the ED

Herpes zoster causes significant morbidity on over 1 million Americans every year. Although the majority of herpes zoster pain will self-resolve within one week, a significant proportion of

neuralgia
bupivacaine
nerve block
dexamethasone
  • 0 views
  • 24 Oct, 2021
  • 1 location
None
The Natural History of Severe Viral Infections and Characterization of Immune Defects in Patients Without Known Immunocompromise

Background Infections caused by viruses are common causes of illnesses: the common cold, many ear infections, sore throats, chicken pox, and the flu are caused by different viruses. Usually, these illnesses last only few days or, at most, a few weeks. Some virus infections like influenza are cleared from the …

cold
adenovirus infection
warts
common cold
ear infections
  • 1033 views
  • 10 Oct, 2021
  • 1 location