Congenital Skin Diseases Clinical Trials

A listing of Congenital Skin Diseases medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 77 clinical trials
Clinical Research on Advanced Warning Factors Of Respiratory Injury in Dermatomyositis

Dermatomyositis (DM) is a highly heterogeneous autoimmune disease characterized by rash and myasthenia. Beside these, respiratory involvement is one of the common complications of DM. Interstitial lung disease (ILD) occur in approximately 90% of patients with DM, part of them may manifest rapidly progressive-interstitial lung disease (rp-ILD), which progresses into …

autoimmune disease
  • 09 Jul, 2021
  • 1 location
International Rare Histiocytic Disorders Registry (IRHDR)

The rare histiocytic disorders (RHDs) are characterized by the infiltration of one or more organs by non-LCH histiocytes. They can range from localized disease that resolves spontaneously, to progressive disseminated forms that can be sometimes life-threatening. Since they are extremely rare, there is limited understanding of their causes and best …

  • 14 Mar, 2021
  • 7 locations
Pulmonary Hypertension Screening for Rheumatology Patients (SOPHIE) (PAH)

Pulmonary arterial hypertension (PAH) is a serious and often fatal complication of connective tissue diseases including systemic sclerosis and systemic lupus erythematosus. It has been reported primarily from European series that the prevalence of PAH in patients with connective tissue diseases particularly systemic sclerosis is as high as 15-20%. However, …

pulmonary arterial hypertension
systemic lupus erythematosus
connective tissue disorder
  • 27 Feb, 2022
  • 1 location
Studies in the Natural History and Pathogenesis of Childhood-Onset and Adult-Onset Idiopathic Inflammatory Myopathies

This study will evaluate subjects with adult- and childhood-onset myositis to learn more about their cause and the immune system changes and medical problems associated with them. Myositis is an inflammatory muscle disease that can damage muscles and other organs, resulting in significant disability. Children or adults with polymyositis or …

pulmonary function test
urine tests
juvenile dermatomyositis
skin inflammation
  • 17 Sep, 2022
  • 4 locations
Studies on the Natural History and Pathogenesis of Polymyositis, Dermatomyositis, and Related Diseases

This study of inflammatory muscle diseases-polymyositis and dermatomyositis and related disorders-will examine what causes these diseases and describe the clinical features (signs and symptoms) associated with them. Inflammation and degeneration of skeletal muscles in these disorders leads to weakness and muscle wasting. The skin, lungs and other organs may also …

pulmonary function test
urine tests
white blood cells
autoimmune disease
biopsy incision
  • 20 Sep, 2022
  • 1 location
Research in the Development of a New Type of Digital Dermatoscope for Skin Cancer (DermScan)

This is a multicenter prospective observational clinical investigation with a medical device. The purpose of this study is to develop and validate of a new type of digital dermatoscope with automatic decision support algorithms. By means of this study a better insight can be gained of the current performance and …

skin cancer
skin lesion
  • 25 Jul, 2022
  • 2 locations
Studies of Natural History, Pathogenesis, and Outcomes in Autoimmune and Inflammatory Diseases Including Juvenile Dermatomyositis

Purpose The purpose of this protocol is 1. To comprehensively evaluate patients with autoinflammatory diseases clinically, genetically and immunologically at the autoinflammatory disease clinic at the NIH. 2. To follow patients with autoinflammatory Diseases that are genetically defined including Neonatal-Onset Multisystem Inflammatory Disease (NOMID), the most severe clinical phenotype of …

blood tests
skin inflammation
  • 23 Sep, 2022
  • 1 location
Examination of Clinical and Laboratory Abnormalities in Patients With Defective DNA Repair: Xeroderma Pigmentosum, Cockayne Syndrome, or Trichothiodystrophy

Four rare genetic diseases, xeroderma pigmentosum (XP), Cockayne syndrome (CS), the XP/CS complex and trichothiodystrophy (TTD) have defective DNA excision repair although only XP has increased cancer susceptibility. We plan to perform careful clinical examination of selected patients with XP, XP/CS, CS, or TTD and follow their clinical course. We …

cancer prevention
Accepts healthy volunteers
  • 19 Sep, 2022
  • 1 location
Myeloproliferative Neoplasms (MPNs) Patient Registry

The mandate of this MPN registry is to collect clinical information, including molecular results, from consenting patients with a variety of MPNs at different time points during the course of their disease.

atypical chronic myeloid leukemia
ringed sideroblasts
myeloproliferative disorder
  • 19 Apr, 2022
  • 1 location
Pregnancy and Medically Assisted Conception in Rare Diseases

Rare diseases frequently affect women of childbearing age. Pregnancy in these women has become less rare, but remains associated with high levels of complications. One obstacle to their optimal management during pregnancy is that there are no prospective studies of pregnancy during rare diseases and several connective tissue diseases. As …

systemic disease
rare diseases
connective tissue disorder
antiphospholipid syndrome
  • 13 May, 2021
  • 2 locations