Congenital Skin Diseases Clinical Trials

A listing of Congenital Skin Diseases medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 76 clinical trials
A Phase Ib Study of Nivolumab in Patients With Autoimmune Disorders and Advanced Malignancies (AIM-NIVO)

This phase Ib trial studies the side effects of nivolumab and to see how well it works in treating patients with autoimmune disorders and cancer that has spread to other places in the body or cannot removed by surgery. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's …

lung cancer
computerized tomography
follicle stimulating hormone
brain metastases
  • 22 Sep, 2022
  • 33 locations
A Phase II Study of Talimogene Laherparepvec Followed by Talimogene Laherparepvec + Nivolumab in Refractory T Cell and NK Cell Lymphomas, Cutaneous Squamous Cell Carcinoma, Merkel Cell Carcinoma, and Other Rare Skin Tumors

This phase II trial studies how well talimogene laherparepvec and nivolumab work in treating patients with lymphomas that do not responded to treatment (refractory) or non-melanoma skin cancers that have spread to other places in the body (advanced) or do not responded to treatment. Biological therapies, such as talimogene laherparepvec, …

gilbert's syndrome
signet ring cell carcinoma
measurable disease
t-cell lymphoma
  • 14 Sep, 2022
  • 6 locations
Doxycycline vs Isotretinoin for Acneiform Eruptions of TKI

Tyrosine Kinase inhibitors (TKIs) have become standard of care in patients with EGFR mutations in non-small cell lung cancer and other EGFR-mutated cancers. However, TKIs are well-known to cause cutaneous adverse events, including acneiform eruptions. Moderate to severe acneiform eruptions are often associated with severe pruritus and pain. Current treatment …

  • 15 Sep, 2021
  • 1 location
Treatment of Pruritus With Intramuscular Promethazine

Neuraxial narcotics are commonly used in obstetric patients for cesarean delivery to help with pain control over the first 24 hours after the surgery. The aim is to evaluate effectiveness of promethazine (IMP) treatment of intrathecal morphine induced pruritus (ITIMIP). A treatment for ITMIP, other than naloxone, will allow for …

  • 26 Sep, 2021
  • 1 location
Therapeutic Effects of Topical Herbal Medicine -Rhubarb Ointment on Rosacea

The aim of this study is to investigate the effects of topical herbal medicine in the patients with rosacea.

  • 29 Sep, 2021
  • 1 location
Study on the Treatment With Water-filtered Infrared-A (wIRA) Radiation in Patients With Morphea and Sclerotic Graft-versus-host Disease

This is a prospective, intra-individual comparative study to evaluate the effectiveness of local-water filtered infrared-A (wIRA) irradiation (applied by Hydrosun radiator 750 for radiation at the clinic, or Hydrosun 575home for home treatment) in patients with morphea or sclerotic GVHD (Graft-versus-host Disease). The purpose of the study is to determine …

  • 21 Jul, 2021
  • 2 locations
Study of Factors Regulating Mast Cell Proliferation

This study will examine growth factors that promote and inhibit mast cell proliferation resulting in mastocytosis, a disease of excessive mast cells in the body. These cells can release chemicals that cause itching, blisters, flushing, bone pain and abdominal pain. Patients up to 80 years of age with mastocytosis may …

Accepts healthy volunteers
  • 10 Aug, 2022
  • 1 location
Deep Learning on 3D Cellular-resolution Tomogram

Skin biopsy is the main method to diagnose skin tumors, skin inflammation, and pigmented diseases. However, biopsy is an invasive method that can cause wounds and scars. Optical coherent tomography (OCT) technology is a fast, non-invasive, non-radioactive, and label-free imaging method. This technology generates real-time images of living tissue by …

Accepts healthy volunteers
  • 07 Jan, 2022
  • 1 location
A Sample Collection Study Utilizing DermTech's Non-invasive Adhesive Patch Biopsy Kits

This sample collection study will recruit subjects with a variety of skin conditions from up to 15 geographically dispersed sites in the United States. Skin samples will be collected with the DermTech Adhesive Patch Kit from both lesional and non-lesional skin. Subjects may also be asked to return at a …

  • 04 Oct, 2022
  • 2 locations
Clinical Research on Advanced Warning Factors Of Respiratory Injury in Dermatomyositis

Dermatomyositis (DM) is a highly heterogeneous autoimmune disease characterized by rash and myasthenia. Beside these, respiratory involvement is one of the common complications of DM. Interstitial lung disease (ILD) occur in approximately 90% of patients with DM, part of them may manifest rapidly progressive-interstitial lung disease (rp-ILD), which progresses into …

autoimmune disease
  • 09 Jul, 2021
  • 1 location