Hypogammaglobulinemia Clinical Trials

A listing of Hypogammaglobulinemia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 9 clinical trials
Double-blind, Randomized, Placebo-controlled, Prospective Phase III Study Evaluating Efficacy and Safety of Panzyga in Primary Infection Prophylaxis in Patients With Chronic Lymphocytic Leukemia ("PRO-SID" Study)

Study Evaluating Efficacy and Safety of Panzyga in Primary Infection Prophylaxis in Patients with Chronic Lymphocytic Leukemia

primary infection
chronic lymphocytic leukemia
igiv
  • 8 views
  • 10 Jul, 2022
  • 29 locations
A Phase I Study of Mozobil in the Treatment of Patients With WHIMS

Background WHIMS (Warts, Hypogammaglobulinemia, Infections, and Myelokathexis Syndrome) is caused by various genetic changes that increase the activity of the

neutropenia
immune globulin
vasectomy
mozobil
severe infection
  • 112 views
  • 20 Jul, 2022
  • 1 location
Immune Disorder HSCT Protocol

This study hypothesizes that a reduced intensity immunosuppressive preparative regimen will establish engraftment of donor hematopoietic cells with acceptable early and delayed toxicity in patients with immune function disorders. A regimen that maximizes host immune suppression is expected to reduce graft rejection and optimize donor cell engraftment.

immune disorder
alemtuzumab
immunosuppression
treatment regimen
filgrastim
  • 125 views
  • 11 May, 2022
  • 1 location
Ocrelizumab VErsus Rituximab Off-Label at the Onset of Relapsing MS Disease (OVERLORD-MS)

This is a multicenter non-inferiority study, designed to establish non-inferiority of the study treatment rituximab compared with the comparator ocrelizumab for consecutively included patients (male or female) with active relapsing-remitting multiple sclerosis aged 18-60 years.

brain mri
rituximab
MRI
ocrelizumab
disease or disorder
  • 0 views
  • 07 Apr, 2022
  • 1 location
Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies

Background Allogeneic blood or marrow transplant is when stem cells are taken from one person s blood or bone marrow and given to another person. Researchers think this may help people with immune system problems. Objective To see if allogeneic blood or bone marrow transplant is safe and effective in …

antibiotics
vaccination
urine tests
immunodeficiency
hypogammaglobulinemia
  • 511 views
  • 23 Jul, 2022
  • 2 locations
COVID-19 Vaccine Responses in PIDD Subjects

The goal of our study is to assess the cellular immune responses of participants with antibody deficiency disease before and after immunization with SARS-CoV-2 mRNA vaccines.

replacement therapy
genetic testing
immune globulin
genetic tests
Accepts healthy volunteers
  • 0 views
  • 20 Apr, 2022
  • 3 locations
Immune Regulation in Patients With Common Variable Immunodeficiency and Related Syndromes

agammaglobulinemia, hypogammaglobulinemia associated with Epstein-Barr infection, and others to better focus on how to correct the underlying defect. Patients with CVI and their family members may participate

malabsorption
antibiotics
anti-inflammatory drugs
blood test
genetic tests
  • 664 views
  • 26 Jul, 2022
  • 1 location
Genetic Studies of Chronic Active Epstein-Barr Disease

Epstein-Barr virus (EBV) is a member of the human herpes virus family that infects more than 95 percent of the U.S. population. Most infections occur in childhood and cause no symptoms; in adolescents and adults, EBV often causes infectious mononucleosis. It has also been associated with certain forms of cancer. …

Accepts healthy volunteers
  • 73 views
  • 08 Aug, 2022
  • 1 location
Tissue Study in Patients Undergoing CAR-T Cell Therapy (CAR_21_01) (CAR_21_01)

The "CAR-T" immunotherapy ("Chimeric Antigen Receptor T cell therapies") is a therapy based on T cells expressing a chemical receptor for a specific antigen indicated for patients with some types of oncohematological pathologies that have not responded to other forms treatment, such as: relapsed or refractory non-Hodgkin's lymphomas, including diffuse …

  • 0 views
  • 21 Apr, 2022
  • 1 location