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Addictions Clinical Trials

A listing of Addictions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (36) clinical trials

Houston Emergency Opioid Engagement System

The purpose of this study is understand how many opioid emergencies are in Houston, to develop an opioid system of care in Houston, and to evaluate if patients who receive both medication assisted treatment (MAT) in the hospital and follow up by emergency medical services (EMS) post-discharge will enroll and ...

Phase

Brexpiprazole Study

STUDY OBJECTIVES The primary objectives of the study include: examine the effect of brexpiprazole treatment on the number of days of substance use in the past week as measured by the Timeline Follow-Back (TLFB) assessment; examine the effect of brexpiprazole treatment on substance craving using 100-mm visual analogue scale (VAS). ...

Phase

Using Imaging to Assess Effects of THC on Brain Activity

Marijuana has become the most popular illicit drug in the western world (Substance Abuse and Mental Health Services Administration, 2004). Both acute and chronic exposure to cannabis is associated with changes in brain activity in frontal, limbic and also cerebellar regions, with generally increased brain activity following acute exposure and ...

Phase

Theta-Burst Stimulation as a Treatment for Reducing Cocaine Use

Objectives: Illicit drug use affects tens of millions of Americans and costs nearly $200 billion annually in health care costs and lost productivity. Cocaine dependence accounts for 25% of reported lifetime drug dependence though few successfully abstain with treatment. For efforts toward positive long-term outcomes, it is imperative to identify ...

Phase

Minocycline and Tobacco Craving in Smokers With Schizophrenia

Nicotine dependence is high in schizophrenia; nearly three times more prevalent than the general population. In smokers with schizophrenia, the risk of all-cause mortality is doubled and cardiovascular mortality risk is twelvefold higher than nonsmokers. Many factors influence smoking in persons with schizophrenia, but predictors of craving and smoking behavior ...

Phase

Nicotine Replacement Therapy in Nicotine-dependent Arrestees

Police custody is a matter of significant public attention in France, as approximately 700,000 people are detained in police cells each year in this country. Tobacco use affects more than 50% of adult arrestees, of which 70% are dependent on nicotine. However, they have no access to tobacco during detention ...

Phase

Alcohol Drinkers' Exposure to Preventive Therapy for TB (ADEPTT)

Tuberculosis (TB) is the leading cause of mortality in persons with HIV worldwide, accounting for 20-33% of HIV-related deaths, and is a high-priority area of research in HIV/AIDS by the NIH. TB preventive therapy decreases both all-cause mortality and active TB in persons with HIV by 30-50% above and beyond ...

Phase

Treatment With Quetiapine for Youth With Substance Use Disorders and Severe Mood Dysregulation

The purpose of this study is to determine whether quetiapine is effective in the treatment of youth with co-occurring substance use disorders and severe mood dysregulation.

Phase

Progesterone and Brain Imaging Study

The purpose of this study is to learn whether a sex hormone called progesterone is helpful in reducing cigarette smoking and craving for cigarettes. This study also includes brain imaging to measure possible effects of progesterone on certain neurochemicals. These neurochemicals are called gamma-aminobutyric acid (or GABA for short) and ...

Phase

Extended-release Naltrexone and Care Management for Alcohol Dependent Frequent Emergency Department Users

Aim #1: To conduct a feasibility and acceptability study of XR-NTX+CM treatment in alcohol dependent patients with frequent ED use. Hypothesis: Enrollment of a limited number of subjects will allow identification of optimal processes for a definitive trial. Aim #2: To conduct an analysis of the effect of this intervention ...

Phase