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Addictions Clinical Trials

A listing of Addictions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (277) clinical trials

Examination of Low Wattage and High Wattage E-Cigarettes

The overall aim of the proposed study is to evaluate the effect of switching from conventional cigarettes to either a LWe or HWe on smoking behavior, product use patterns and continued use, as well as biomarkers of toxicant exposure and effects.

Phase N/A

Remifentanil for Preventing Propofol Injection Pain in Elderly Patients

Elderly patients show different pharmacokinetic and pharmacodynamic variables and usually need smaller doses of anesthetic drugs than younger patients. The purpose of this study was to investigate the optimal effect-site concentration of remifentanil for preventing injection pain during propofol induction in elderly patients by the Dixon's up-and-down method.


Naloxone to TReatment Entry in the Emergency Setting

Randomized controlled trial. Subjects are included if they are being treated by an ambulance in the Malm uptake are for an opioid overdose requiring naloxone antidote administration, and if they sign informed written consent to the study. Subjects are randomized by ambulance staff to either an active intervention, or a ...

Phase N/A

Patients are needed to participate in a clinical research study of Bipolar II Disorder, Cannabis Use Disorder, Drug abuse, Bipolar I Disorder to evaluate Placebo Oral Capsule, Gabapentin

Bipolar disorder (BD) is the Axis I condition most strongly associated with cannabis use disorder (CUD); there is a six-fold increase in the prevalence of CUD in individuals with BD relative to the general population. Individuals with co-occurring CUD and BD (CUD+BD) have substantially worse clinical outcomes than those with ...


Master Mind Program Evaluation Study

The purpose of this study is to conduct a randomized controlled trial to evaluate the efficacy of the Master Mind program, a mindfulness education substance abuse prevention program. The program has the goal of enhancing coping strategies and decision-making skills and preventing substance abuse in late elementary school students.

Phase N/A

The Efficacy of Therapy Focused on Desire-satisfaction for Disordered Gamblers

Introduction Gambling disorder is a public health problem characterized by persistent and recurrent maladaptive patterns of gambling. A prevalence rate was 0.4-2.0% worldwide. In Japan, gambling is common: the prevalence rate of disordered gamblers is estimated to be 5.5% of adults.Gambling disorder resulted in clinical and subclinical harms, which are ...

Phase N/A

The Gender-Sex Hormone Interface With Craving & Stress-Related Changes in Smoking

Despite considerable advances in treatment development, cigarette smoking remains the leading cause of preventable death in the United States, and most smokers engaged in treatment are unsuccessful in quitting. The burden of illness is disproportionately borne by female smokers, who are less responsive to cessation interventions than males. The relationships ...

Phase N/A

Brief Intervention for Rural Women at High Risk for HIV/HCV

Specific Aim 1: Compare the effectiveness of an evidence-based HIV risk reduction intervention (MI-HIV) to HIV Education (NIDA Standard) in reducing sex risk behaviors, injection practices, and drug use among a culturally unique sample of disadvantaged, drug-using rural women at high-risk for HIV and HCV. This aim will be accomplished ...

Phase N/A

Nicotine Dependence Withdrawal and Replacement Therapy Assessed by PET Imaging

While smoking prevalence has declined for both men and women over the last two decades, rates among women have shown a much shallower decrease and, in recent years, prevalence of cigarette initiation has been higher for girls than boys. Smoking among women of child-bearing age has significant negative health consequences ...


Bilateral Prefrontal Modulation in Crack-cocaine Addiction

Before (baseline) and after tDCS or sham-tDCS treatment, subjects will be examined: clinically, regarding craving (obsessive compulsive scale), depressive (Hamilton depression rating scale) and anxiety (Hamilton anxiety rating scale) symptoms and quality of life of the World Health Organization (WHOQOL-BREF); cognitively, regarding frontal (Frontal assessment battery), mental state (mini-mental status ...