Addictions Clinical Trials

A listing of Addictions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 410 clinical trials
Potential Effects of Electronic Nicotine Delivery System Flavor Regulations on African American Menthol Smokers (RVA Flavors)

This study aims to better understand how the availability of electronic nicotine delivery system (aka electronic cigarettes) flavors (e.g., menthol, tobacco) impacts tobacco use behaviors, toxicant exposure, and abuse liability among African American menthol smokers.

Accepts healthy volunteers
  • 0 views
  • 15 May, 2022
  • 1 location
Virtual Reality in SOD

Patients with classic type-3 Sphincter of Oddi dysfunction have chronic debilitating pain not amenable to pharmacologic or endoscopic therapy. Previous studies have shown benefits of virtual reality (VR) for pain management through immersive three-dimensional (3D) multisensory experiences, but only in short-term inpatient settings. The impact of VR for chronic pain …

  • 413 views
  • 15 Feb, 2022
  • 1 location
LSD Base and LSD Tartrate Bioequivalence and Bioavailability in Healthy Subjects (LSD-Bio)

Lysergic acid diethylamide (LSD) is used as recreational substance and as a research substance to study the mind. Recreationally, LSD is typically used in the form of "blotters" containing LSD tartrate. In research, both LSD base (LSD alone) or LSD salt in the form of LSD tartrate are used. The …

Accepts healthy volunteers
  • 0 views
  • 23 Apr, 2022
  • 1 location
Regional Partnership for Pregnant Women at Risk of Substance Misuse and Their Newborns

This study recruits pregnant women and new mothers who are at risk of substance use concerns during pregnancy or delivery. These women are followed for 6 months and randomized into two groups; they may receive services as usual, or enhanced services. Enhanced services include evidence based interventions and case management …

Accepts healthy volunteers
  • 0 views
  • 03 Jun, 2022
  • 1 location
Combating Craving With Contingency Management: Neuroplasticity and Methamphetamine Abuse in South Africa

This study will correlate MA-abstinence outcomes from an 8-week contingency management (CM) program of voucher- based incentives using an escalating schedule that has been successfully implemented as an adjunct to MA treatment by the investigators collaborators in the United States. Pre- and post- treatment neuroimaging and neurocognitive assessments will assist …

  • 319 views
  • 08 Nov, 2020
  • 1 location
Medication Maintenance Therapy in Community Pharmacy Settings (MATPharm)

The goal of this study is to compare pharmacy-based medication assisted treatment (MAT) with usual care MAT for people with opioid use disorder.

Accepts healthy volunteers
  • 0 views
  • 17 Feb, 2022
Effects of MDMA Co-administration on the Response to LSD in Healthy Subjects

The acute subjective effects of serotonin (5-HT)2A receptor stimulation with lysergic acid diethylamide (LSD) in humans are mostly positive. However, negative effects such as anxiety, paranoid thinking or loss of trust towards other people are common effects, depending on the dose administered, the personality traits of the person consuming it …

  • 36 views
  • 18 Sep, 2021
  • 1 location
Imaging CRF X NOP Interactions in CUD

This study uses [11C]NOP-1A positron emission tomography (PET) and a hydrocortisone challenge to image the interaction between nociceptive opioid peptide (NOP) receptors and cortisol/corticotrophin releasing factor (CRF) in subjects with cocaine use disorders (CUD) and matched healthy controls (HC). It will also examine whether alterations in CRF x NOP interactions …

  • 0 views
  • 12 Sep, 2021
  • 1 location
[C-11]NPA PET-amphetamine in Cocaine Use Disorders

This study uses [11C]NPA positron emission tomography (PET) and a d-amphetamine challenge to image amphetamine induced dopamine release in the striatum in subjects with cocaine use disorders (CUD). Amphetamine-induced dopamine release data from this study will be correlated with [11C]NOP-1A VT measured at baseline in the midbrain. [11C]NOP-1A PET data …

  • 0 views
  • 12 Sep, 2021
  • 1 location
Dissecting the Heterogeneity of Oral Cancer Pain

Oral squamous cell carcinoma (SCC) produces a higher prevalence and more severe pain than all other cancers. Orofacial pain is one of the most common initial symptoms of oral cancer and often leads to the diagnosis of oral cancer. However, the character, severity, and unique features of oral cancer widely …

  • 0 views
  • 04 Sep, 2021
  • 1 location