Addictions Clinical Trials

A listing of Addictions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
I am looking for
added new label for I am looking for
Advanced Filters
Found 457 clinical trials
Topiramate and Schizophrenia: Effects on Weight and Psychopathology

Clozapine is the sole AP agent with superiority in treatment refractory schizophrenia, but it also is associated with the greatest risk of weight gain and other metabolic abnormalities. Topiramate, an anticonvulsant agent, possesses a weight-reducing effect. Furthermore, some studies have suggested that Topiramate may be associated with improvements in psychopathology …

  • 23 Feb, 2022
  • 1 location
Group Intervention to Improve Parent-Adolescent Relationships

This pilot randomized control trial investigates whether a psychosocial intervention targeting parent-adolescent conflict is feasible and acceptable, in preparation for a future trial that will test whether the intervention can improve treatment outcomes for youth diagnosed with depression.

depressive disorder
depressed mood
  • 19 Sep, 2021
  • 1 location
Enhancing Frontal Lobes Plasticity in Mild Cognitive Impairment (PAS-MCI)

More than 5 million people live with Alzheimer's dementia (AD) in North America. No effective treatment exists yet probably because by the time AD has developed it is too late to intervene. Mild Cognitive Impairment (MCI) is a clinical state that typically precedes AD. In MCI, the prefrontal cortex supports …

Accepts healthy volunteers
  • 25 Jan, 2022
  • 1 location
Pharmacologically-based Strategies for Opioid Substitution Therapy During Pregnancy

This study will evaluate maternal tolerance to several BUP dose reduction strategies.

illicit drugs
withdrawal symptom
opioid substitution
  • 05 Jul, 2022
  • 2 locations
Clinical Trial of Nabilone for Aggression in Adults With Intellectual and Developmental Disabilities (N-AND)

Innovative treatments are urgently needed for severe behavioural problems (SBPs) in adults with intellectual and developmental disabilities (IDD). Although a synthetic cannabinoid, nabilone may be a plausible and safe alternative to treat SBP, safety and efficacy of nabilone in people with IDD has never been evaluated. The investigators propose to …

  • 19 Apr, 2022
  • 1 location
Onsite Buprenorphine Treatment at Syringe Exchange Programs (O-BMT)

This trial will recruit syringe exchange participants with opioid use disorder in New York City and test whether starting buprenorphine treatment at the syringe exchange program is more effective than referral to a community health center for buprenorphine treatment.

narcotic use
opioid use disorder
  • 21 Mar, 2022
  • 3 locations
Extended Effects of Cannabis Abstinence on Clinical Symptoms and Cognition in Depression

The prevalence of major depressive disorder (MDD) is ~5.0%, and rates of co-occurring SUDs in these patients approach 40-50%. Specifically, rates of co-morbid cannabis use disorder (CUD) in patients with MDD are elevated 2-3 fold compared to 2.9% in the general population, and is associated with poorer treatment outcomes and …

  • 01 Jul, 2021
  • 1 location
rTMS for Depression in Young Adults With Autism

The current clinical trial is focused on evaluating the efficacy of rTMS for treatment of depression in youth and young adults (hereafter called transition aged youth, TAY) with autism spectrum disorder (ASD). The motivation to undertake the current efficacy study is driven by: (1) the substantial impact of depression on …

  • 01 Aug, 2021
  • 1 location
"Extended" (Alternate Day) Antipsychotic Dosing

The study wishes to examine whether "extended" antipsychotic treatment, in this case, antipsychotic treatment every other day, is as effective as daily treatment. It is also evaluating whether there may be differences in terms of side effects. Participants will be randomly assigned to either the treatment as usual group (i.e., …

  • 10 Aug, 2022
  • 1 location
Impact of a Brief Motivational Intervention Including Counter-marketing Arguments With a Population of Patients With Moderate to Severe Alcohol Use Disorders Who Are Followed up on an Outpatient Basis (Primary Care or Addictology) (DEPREV_Phase 3)

Alcohol consumption is the second cause of avoidable death after tobacco. The Evin law was constructed in 1991 with the aim of reducing exposure to alcohol marketing among the youngest. But this law is currently extremely weakened, and in a press release of February 26, 2018, the French Alcohol Society …

  • 24 Mar, 2022
  • 3 locations