Addictions Clinical Trials

A listing of Addictions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 441 clinical trials
Long-acting Naltrexone for Pre-release Prisoners

This proposed five-year study will focus on whether the addition of providing XR-NTX treatment at a patients' place of residence will increase adherence and thus efficacy of the medication.Following initial screening, informed consent, and medical examination, pre-release prisoners at each facility will be block randomized (N=240) within gender to either: …

naltrexone
analgesics
buprenorphine
opiates
vivitrol
  • 17 views
  • 25 Feb, 2022
  • 1 location
The Effects of tDCS on Illness Awareness in Schizophrenia

This is a novel study that seeks to explore the clinical and functional imaging effects of transcranial direct current stimulation (tDCS) on illness awareness or anosognosia in schizophrenia, arguably the most treatment-resistant manifestation of the disorder.

antipsychotics
schizoaffective disorder
transcranial direct current stimulation
  • 2 views
  • 20 Jun, 2022
  • 1 location
rTMS for Suicidality in Opioid Use Disorder

This trial is a randomized, double blind, controlled pilot study that will compare bilateral theta burst stimulation (TBS) and sham treatment for patients with opioid use disorder (OUD) and Major Depressive Disorder (MDD) experiencing suicidality.

  • 0 views
  • 25 Mar, 2022
  • 1 location
Reactivity of the Vestibular System to Caloric Vestibular Stimulation in Schizophrenia

This study aims to determine if individuals with schizophrenia have greater reactivity to vestibular stimulation than healthy controls. The physiological response of vestibular stimulation will be assessed with electronystagmography, which provides a measure of the intensity of the nystagmus via PSPV. Positive results would suggest greater vestibular system reactivity to …

psychiatric disorder
schizoaffective disorder
Accepts healthy volunteers
  • 1 views
  • 13 Jun, 2022
  • 1 location
Switching From Twice-Daily to Once-Daily Clozapine Dosing in Schizophrenia

Plasma half-life has routinely been used to establish the dosing schedule of antipsychotics; for example, it is recommended that agents with a short plasma half-life be administered multiple times per day. However, to date, several randomized controlled trials (RCTs) have shown no differences in clinical outcomes between once- and twice-daily …

antipsychotics
schizophrenia
schizoaffective disorder
clozapine
  • 141 views
  • 23 Feb, 2022
  • 1 location
Naltrexone in AUD Reward Drinkers

This study is a phase IV, two-arm, randomized, double-blind, placebo-controlled study to assess whether individuals identified as primarily reward drinkers are significantly more likely to reduce heavy drinking if they receive XR-NTX than a matching placebo injection. Study subjects will receive monthly injections of long-acting injectable naltrexone 380 mg (4 …

  • 0 views
  • 15 Jun, 2022
  • 1 location
Contingency Management for Cannabis Use for Persons With HIV

The purpose of this study is to determine the feasibility and impact of 28-days of monitored abstinence from cannabis use on symptoms of depression and anxiety, pain, sleep, cannabis use withdrawal, HIV viral load and biomarkers of systemic inflammation among PLWH and who use cannabis regularly (weekly or more often). …

hiv viral load
HIV Vaccine
  • 0 views
  • 15 Mar, 2022
  • 1 location
Ketone Ester Intervention in Alcohol Use Disorder

The purpose of this research is to study how a nutritional ketone ester may effect brain function and alcohol consumption in regular alcohol users. The study will see how the brain responds, once after drinking the ketone ester and once after drinking a "placebo", which will look and taste the …

  • 67 views
  • 04 Oct, 2022
  • 1 location
Relationship Between Brain and Heart Glucose Metabolism in Alcohol Use Disorder

The goal of this study is to learn more about how a nutritional supplement "ketone ester" (deltaG ®) has an effect on brain and heart function and on alcohol consumption in individuals with and without alcohol use disorder. The study will use Fluorodeoxyglucose (FDG) Positron Emission Tomography/Computed Tomography (PET/CT) scans …

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Community-based Cognitive Remediation and tDCS to Enhance Seniors' Function and Mental Health (CREAtE)

Focusing on seniors with mental health conditions who are living in the community, this initiative proposes to assess the acute and long-term effects of an 8-week course of daily (5 days/week) cognitive remediation (CR) training among 270 participants living in five LOFT senior housing units. The acute course of CR …

  • 0 views
  • 14 Apr, 2022
  • 1 location