Addictions Clinical Trials

A listing of Addictions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 446 clinical trials
Control Network Neuromodulation to Enhance Cognitive Training in Complex Traumatic Brain Injury (CONNECT-TBI)

The CONNECT-TBI Trial aims to develop safe, effective treatments for complex mTBI that improve cognitive functioning. Based on the compelling preliminary data generated by our study team, the objective of this study is to conduct a randomized, double-blinded, sham-controlled Phase II clinical trial of APT-3 combined with rTMS, HD-tDCS, or …

traumatic brain injury
brain stimulation
cognitive rehabilitation
cognitive training
  • 23 Mar, 2022
  • 2 locations
Connettive Tissue Graft Versus Collagen Matrix.

Despite the potential role of soft tissue thickness in maintaining gingival margin stability, the existing literature has mainly focused on investigating the effect of different surgical techniques on recession coverage percentage, without taking into account the changes in tissue thickness and biotype in the surgical area. Hence, this study aims …

Accepts healthy volunteers
  • 14 May, 2022
  • 1 location
Adjunct Treatment With Cariprazine for Adults With Attention-deficit/Hyperactivity Disorder

According to the Canadian ADHD Practice Guidelines, psychostimulants are the preferred treatment of attention-deficit/hyperactivity disorder (ADHD), especially for those that require urgent care. Specifically, long-acting psychostimulants are considered the gold-standard pharmacological treatment for ADHD. Using extended-release formulations, long-acting psychostimulants provide an extended duration of daily symptom relief in addition to …

  • 19 Dec, 2021
  • 1 location
Sleep and Emotional Reactivity in Alcohol Use Disorder

Alcohol use disorder (AUD) is a multifaceted, chronic relapsing disorder suffered by millions of men and women in the United States. AUD is associated with disrupted sleep continuity and architecture, which impact health-related quality of life, and contribute to relapse. However, many alcohol-sleep interactions and their underlying mechanisms remain unclear, …

  • 09 Aug, 2021
  • 1 location
Smartwatches to Manage Stress and Anxiety in Residential Settings (Smartwatch)

The purpose of the study is to conduct a prospective evaluation of a smartwatch technology and an associated application (developed by Awake Labs) in a clinical cohort from CAMH Adult Neurodevelopmental Services (ANS) and adults with developmental disabilities in the community who have received a watch.

  • 30 May, 2022
  • 1 location
Neural Correlates of Ketamine's Anti-suicidal Effects in Bipolar Depression (DEEPP)

Bipolar disorder is characterized by manic episodes and episodes of extreme depressive feelings, also known as bipolar depression (BD). Although clinical data does not suggest significant differences in the severity of depressive symptoms between bipolar and unipolar depression, patients with BD are found to be more likely to experience suicidal …

depressive episode
depressed mood
  • 25 Jul, 2022
  • 1 location
Ibudilast for the Treatment of Alcohol Use Disorder

This study is a double-blind, placebo-controlled randomized clinical trial of IBUD (50mg BID) for the treatment of Alcohol Use Disorder (AUD). Eligible participants will undergo a 12-week medication treatment period and 5 in-person visits over 16 weeks.

  • 15 Feb, 2022
  • 1 location
The Effects of Non-invasive Brain Stimulation on Treatment Adherence in Schizophrenia

This study seeks to explore the effects of transcranial direct current stimulation (tDCS), a non-invasive method of brain stimulation, as an adjunctive treatment to improve antipsychotic medication adherence in patients with schizophrenia (SCZ). The investigators hypothesize that 20 sessions of tDCS will improve medication nonadherence in patients with SCZ.

  • 14 Jun, 2022
  • 1 location
Clinical and Mechanistic Effects of Psilocybin in Alcohol Addicted Patients

Effects of serotonin 2A/1A receptor stimulation by psilocybin on alcohol addicted patients: a randomized double-blind placebo-controlled study

psychotropic drugs
  • 02 Jun, 2022
  • 1 location
Exercise in Extended Oncogene Addicted Lung Cancer in Active Treatment (EXcellenT)

This is an interventional, non-pharmacologic, randomized controlled study evaluating the impact on quality of life of a personalized exercise program in oncogene addicted lung cancer patients undergoing active treatment. Patients will be randomized 1:1 in two arms: arm A (interventional) and arm B (control). The program of physical activity will …

proto-oncogene tyrosine-protein kinase ros
cancer chemotherapy
  • 23 May, 2022
  • 1 location