Addictions Clinical Trials

A listing of Addictions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 441 clinical trials
Initial Management of MRONJ Stages I and II a Clinical Trial With Detection of Salivary Biomarkers

Medication-related osteonecrosis of the jaw (MRONJ) is a serious complication in patients receiving antiresorptive therapies, such as Bisphosphonates and Denosumab. It is defined by the presence of exposed bone or a fistula that probes bone in the jaws for a period greater than 8 weeks in patient with a history …

  • 24 Feb, 2021
  • 1 location
Efficacy Study of a New Individualized Rehabilitation Programme for Social Cognition in Patients With Schizophrenia

Patients affected by schizophrenia often present significant deficits in various aspects of social cognition, such as social perception, recognition of one's own and other people's emotional state and the theory of mind. Recent studies investigated the correlation between social cognition and real-life functioning, reporting that greater social cognition deficits determine …

schizoaffective disorder
psychiatric treatment
cognitive remediation
  • 18 Dec, 2021
  • 1 location
Incidence of Acute Urine Retention: Randomized Clinical Trial Comparing Early Mid or Late Urinary Catheter Removal in Patients With Rectal Resection

DESIGN Randomized, open-label and parallel clinical trial, assigned to early, mid, or late withdrawal of urinary catheter with a 1: 1: 1 allocation ratio. POPULATION Patients undergoing anterior rectal resection, low rectal resection, or abdominoperineal amputation for any reason. OBJECTIVES The main objective is to compare the incidence of acute …

  • 19 Feb, 2021
  • 1 location
Alcoholic Liver Disease and the Gut Microbiome

Background: Significant sex differences exist in regard to alcohol use disorder (AUD) and alcoholic liver disease (ALD). To date, no studies have examined the brain-gut-microbiome (BGM) axis (which is the relationship between the gut, brain, and the bacteria within the gut) and sex-differences in AUD and ALD. Aims: 1) Demonstrate …

Accepts healthy volunteers
  • 30 May, 2022
  • 1 location
Cannabidiol for Fibromyalgia (The CANNFIB Trial)

Fibromyalgia is serious chronic pain condition which is often accompanied by sleep disturbances, fatigue and disability and reduced quality of life. There is no cure and treatments are based on reliving symptoms and maintaining function. The currently available medical treatments are not helping many patients, and many get side-effects. Medical …

sham treatment
chronic pain
  • 20 Sep, 2021
  • 1 location
Control Network Neuromodulation to Enhance Cognitive Training in Complex Traumatic Brain Injury (CONNECT-TBI)

The CONNECT-TBI Trial aims to develop safe, effective treatments for complex mTBI that improve cognitive functioning. Based on the compelling preliminary data generated by our study team, the objective of this study is to conduct a randomized, double-blinded, sham-controlled Phase II clinical trial of APT-3 combined with rTMS, HD-tDCS, or …

cognitive deficits
traumatic brain injury
cognitive training
brain stimulation
cognitive rehabilitation
  • 23 Mar, 2022
  • 2 locations
Connettive Tissue Graft Versus Collagen Matrix.

Despite the potential role of soft tissue thickness in maintaining gingival margin stability, the existing literature has mainly focused on investigating the effect of different surgical techniques on recession coverage percentage, without taking into account the changes in tissue thickness and biotype in the surgical area. Hence, this study aims …

Accepts healthy volunteers
  • 14 May, 2022
  • 1 location
Adjunct Treatment With Cariprazine for Adults With Attention-deficit/Hyperactivity Disorder

According to the Canadian ADHD Practice Guidelines, psychostimulants are the preferred treatment of attention-deficit/hyperactivity disorder (ADHD), especially for those that require urgent care. Specifically, long-acting psychostimulants are considered the gold-standard pharmacological treatment for ADHD. Using extended-release formulations, long-acting psychostimulants provide an extended duration of daily symptom relief in addition to …

  • 19 Dec, 2021
  • 1 location
Sleep and Emotional Reactivity in Alcohol Use Disorder

Alcohol use disorder (AUD) is a multifaceted, chronic relapsing disorder suffered by millions of men and women in the United States. AUD is associated with disrupted sleep continuity and architecture, which impact health-related quality of life, and contribute to relapse. However, many alcohol-sleep interactions and their underlying mechanisms remain unclear, …

  • 09 Aug, 2021
  • 1 location
Smartwatches to Manage Stress and Anxiety in Residential Settings (Smartwatch)

The purpose of the study is to conduct a prospective evaluation of a smartwatch technology and an associated application (developed by Awake Labs) in a clinical cohort from CAMH Adult Neurodevelopmental Services (ANS) and adults with developmental disabilities in the community who have received a watch.

  • 30 May, 2022
  • 1 location