Addictions Clinical Trials

A listing of Addictions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 441 clinical trials
Telephone All Nations Breath of Life (tANBL)

This project formally test an individual, telephone-based version of the All Nations Breath of Life smoking cessation program (tANBL) for American Indians (AI) for efficacy versus an untailored comparison program (CP). The primary outcome is 7-day point prevalence abstinence from smoking cigarettes at 6 months post-baseline. Secondarily, the study examines …

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Preventing Persistent Post-Surgical Pain and Dysfunction

Primary Aim: To examine the superior efficacy of ACT versus Attention Control (AC) on postoperative pain intensity and functioning in at-risk Veterans undergoing TKA. Changes in pain intensity and functioning from baseline to 6 weeks, 3 months and 6 months post-TKA will be compared. Level of pain intensity will be …

anxiety symptoms
depression
depressed mood
postoperative pain
total knee replacement
  • 43 views
  • 25 Feb, 2022
  • 1 location
Role of Pharmacotherapy in Counteracting Weight Regain in Adolescents With Severe Obesity

Long-term weight loss maintenance is seldom achieved by individuals with obesity owing to numerous biological adaptations occurring in the post-weight loss setting, including neuroendocrine-mediated changes in appetite/satiety and reduction of energy expenditure. Following weight loss, peripheral and central mechanisms respond in a way similar to starvation by conveying a sense …

topiramate
  • 3 views
  • 01 Nov, 2021
  • 1 location
Theta Burst Stimulation as a Tool to Decrease Drinking in Treatment-seeking Alcohol Users

There is growing interest in the utilization of transcranial magnetic stimulation (TMS) as a novel, non-pharmacologic approach to decreasing alcohol use among treatment-seeking individuals with Alcohol Use Disorder (AUD). The results of this study will be used to determine which of the 2 proposed TMS strategies has a larger effect …

heavy drinking
alcohol use disorder
anxiety
  • 0 views
  • 04 Oct, 2022
  • 1 location
Androgen Excess as a Cause for Adipogenic Dysfunction in PCOS Women

The purpose of this research study is to collect specimen samples and study medical information from women with Polycystic Ovary Syndrome (PCOS) and women without PCOS. The goal is to learn more about the changes that take place in the body that result in PCOS. We anticipate that 32 women …

acne
flutamide
glucose tolerance test
Accepts healthy volunteers
ovarian dysfunction
  • 1045 views
  • 23 May, 2022
  • 1 location
Prevention of Opioid Use Disorder After Surgery

The objective of this study is to design, implement, and pilot test a multi-faceted intervention to support safer opioid prescribing, self-administration, and monitoring and reduce persistent opioid use and opioid use disorder for patients transitioning to the community setting after major orthopedic surgery. The multi-faceted intervention includes: 1) communication with …

morphine
self-administration
opioid
opioid use disorder
opioid use
  • 0 views
  • 04 Oct, 2022
  • 1 location
Efficacy of Ibuprofen Chronotherapy in Healing After Surgical Extraction of the Mandibular Third Molar

Clinical and preclinical studies have demonstrated encouraging results of non-steroidal anti-inflammatory drug (NSAID) chronotherapy in the management and treatment of inflammatory diseases such as rheumatoid arthritis. However, no previous clinical trials have addressed how the timing of NSAID administration within the day affects pain and healing outcomes after oral surgery …

NSAID
ibuprofen
Accepts healthy volunteers
  • 14 views
  • 12 Feb, 2022
  • 1 location
Pain Avoidance Behavior and Its Relation to Risk for Opioid Use in Chronic Pain Patients

This study is designed to find behavioral and neurophysiological correlates of pain avoidance behavior among chronic pain patients, controlling for risk for opioid use disorder. Further, traits and risk factors that contribute to pain avoidance behavior will be investigated. The knowledge gained will broaden the current understanding of mechanisms involved …

Accepts healthy volunteers
opioid
anxiety
chronic pain
  • 0 views
  • 04 Oct, 2022
  • 1 location
Initial Management of MRONJ Stages I and II a Clinical Trial With Detection of Salivary Biomarkers

Medication-related osteonecrosis of the jaw (MRONJ) is a serious complication in patients receiving antiresorptive therapies, such as Bisphosphonates and Denosumab. It is defined by the presence of exposed bone or a fistula that probes bone in the jaws for a period greater than 8 weeks in patient with a history …

  • 0 views
  • 24 Feb, 2021
  • 1 location
Efficacy Study of a New Individualized Rehabilitation Programme for Social Cognition in Patients With Schizophrenia

Patients affected by schizophrenia often present significant deficits in various aspects of social cognition, such as social perception, recognition of one's own and other people's emotional state and the theory of mind. Recent studies investigated the correlation between social cognition and real-life functioning, reporting that greater social cognition deficits determine …

schizoaffective disorder
psychiatric treatment
cognitive remediation
schizophrenia
  • 0 views
  • 18 Dec, 2021
  • 1 location