Addictions Clinical Trials

A listing of Addictions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 24 clinical trials
Development Of Neuroimaging Methods To Assess The Neurobiology Of Addiction

Background Abusing alcohol, drugs, and other substances can cause serious health problems. These substances also can affect brain function. Researchers want to learn more about brain function by using magnetic resonance imaging (MRI). This uses a magnetic field and radio waves to take pictures of the brain. Objective To develop …

  • 26 views
  • 16 Jun, 2021
  • 1 location
Suvorexant and Cocaine

neuroscience research on cocaine addiction by focusing on orexin, which has strong preclinical evidence supporting its critical role in addiction but remains unstudied in humans.

  • 4 views
  • 12 Jun, 2021
  • 1 location
Evaluation of Psilocybin in Anorexia Nervosa: Safety and Efficacy

The primary aim of this study is to assess the safety and tolerability of one 25 mg dose of psilocybin in participants with anorexia nervosa based on adverse events (AEs), changes in vital signs, electrocardiograms (ECGs) and clinical laboratory tests. The secondary objectives are to explore the efficacy of a …

  • 0 views
  • 15 Jun, 2021
  • 1 location
Oxytocin Stress Craving Opioid Use Disorder

Although stress has long been linked to substance use, craving and relapse, there are no available medications that target stress-induced substance use disorder (SUD). In particular, with the rise in opioid use, there is still a crucial need for developing effective pharmacological treatments that target and integrate the complexity of …

opiates
narcotic use
buprenorphine
substance use
oxytocin
  • 84 views
  • 14 Jun, 2021
  • 1 location
Transcranial Magnetic Stimulation (rTMS) as a Tool to Decrease Pain and Improve Functioning

Despite the availability of opioid replacement therapies, many opioid use disordered Veterans are not able to remain abstinent. Repetitive Transcranial Magnetic Stimulation (rTMS) is a non-invasive neuromodulation technique with a consistent, rapidly expanding literature base reporting positive outcomes in substance using populations. This pilot application will investigate a novel multi-session …

chronic pain
opioid substitution
benzodiazepines
narcotic use
  • 6 views
  • 16 Jun, 2021
  • 1 location
Biased Opioid Agonists for Treatment of Opioid Withdrawal in OUD

Background People with opioid-use disorder (OUD) might benefit from having more treatment drugs to choose from. A new drug, TRV734, could be used like methadone to treat OUD. It might not have as many side effects. Objective To test if TRV734 relieves withdrawal symptoms and has fewer side effects than …

  • 0 views
  • 16 Jun, 2021
  • 1 location
Advanced Functional and Structural MRI Techniques for Neuropharmacological Imaging

when engaged in specific tasks. MRI scans have provided more information about how drugs affect the brain, and about how drug addiction changes the brain and influences behavior, mood, and thinking

breathalyzer test
drug use
addiction
brain imaging
drug dependence
  • 488 views
  • 17 Jun, 2021
  • 1 location
Brain Exercise and Addiction Trial

Heavy cannabis use is associated with substantive learning and memory impairments and elevated risk of psychopathology. It has been repeatedly demonstrated that the hippocampus, centrally implicated in these processes, is particularly vulnerable to the deleterious effects of prolonged exposure to cannabis. This deterioration of hippocampal structure, function, and biochemistry can …

  • 0 views
  • 05 Jun, 2021
  • 1 location
A Study to Assess 18-Methoxycoronaridine

The primary objective of this study is to assess the safety and tolerability of a single day dosing and a separate multiple day dosing of 18-MC HCl administered orally, each part of the study having a different set of healthy male and female volunteers.

hysterectomy
hormonal contraception
  • 40 views
  • 17 Jun, 2021
  • 1 location
The Role of Nicotine and Non-Nicotine Alkaloids in E-Cigarette Use and Dependence

they may lead to continued use of conventional cigarettes known to be extremely harmful to health. Cigarette addiction critically involves a dependence on nicotine, but it is likely that other tobacco

illicit drugs
tobacco smoke
addiction
illegal drug
smoking cessation therapy
  • 0 views
  • 04 Jun, 2021
  • 1 location