Multiple Myeloma Clinical Trials

A listing of Multiple Myeloma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 155 clinical trials
Carfilzomib Thalidomide and Dexamethasone in Patients With Relapsed and/or Refractory Multiple Myeloma

All patients with multiple myeloma (MM) are destined to relapse even with the best available approved agents. Median OS from diagnosis in the current era is reported at 5.4 years. Given that

  • 22 views
  • 21 Jan, 2021
  • 1 location
Study of Early Relapsed Lenalidomide-refractory Subjects Eligible for Carfilzomib Triplet

A Study Evaluating Treatment of Multiple Myeloma with Carfilzomib in Combination with Pomalidomide and Dexamethasone

  • 0 views
  • 18 Jun, 2021
  • 37 locations
Non-Myeloablative Allogeneic Transplantation From Unrelated Donors in Multiple Myeloma

The protocol aims at reducing transplant toxicity and mortality in patients with multiple myeloma.

cell transplantation
  • 4 views
  • 07 Nov, 2020
  • 1 location
RAPA-201 T Cell Therapy for Relapsed Refractory Multiple Myeloma

RAPA-201-RRMM is an open-label, single-arm, non-randomized multicenter Phase II study of RAPA-201 autologous T cells in adults with relapsed, refractory multiple myeloma who have received at

  • 0 views
  • 02 Feb, 2021
  • 1 location
SELIBORDARA: Selinexor Bortezomib and Daratumumab in Multiple Myeloma

Phase 2, single-arm, open, non-randomized, multicenter study of the SINE compound selinexor plus low-dose dexamethasone, in combination with bortezomib and daratumumab. 100 mg selinexor (on days 1, 8, 15 and 22), plus 40 mg dexamethasone (20 mg IV the day of daratumumab and selinexor and 20 mg oral administration the …

growth factor
monoclonal antibody therapy
proteasome inhibitor
lenalidomide
neutrophil count
  • 16 views
  • 15 Feb, 2021
  • 15 locations
Thalidomide Cyclophosphamide Oral Idarubicin and Dexamethasone (T-CID) in Patients With Multiple Myeloma

Background: In some studies, thalidomide in combination with chemotherapy has been shown to be effective in patients with relapsed or refractory multiple myeloma (MM). In this study, the

refractory multiple myeloma
cyclophosphamide
cell transplantation
plasma cell leukemia
dexamethasone
  • 8 views
  • 07 Nov, 2020
  • 1 location
PAD Combination Therapy Followed by Thal/Dex for Relapsed or Refractory Multiple Myeloma

Prospective multicenter phase 2 study using PAD and Thal/Dex combination sequentially.

refractory multiple myeloma
dexamethasone
cell transplantation
thalidomide
velcade
  • 6 views
  • 07 Nov, 2020
  • 1 location
Daratumumab Pomalidomide and Dexamethasone in Treating Patients With Relapsed Multiple Myeloma

This phase II trial studies how well daratumumab, pomalidomide, and dexamethasone work in treating patients with multiple myeloma that has come back (relapsed). Immunotherapy with daratumumab

proteasome inhibitor
lenalidomide
monoclonal antibodies
measurable disease
immunoglobulin
  • 0 views
  • 16 Apr, 2021
  • 10 locations
Pomalidomide Ixazomib and Dexamethasone With or Without Intensification by Cyclophosphamide in Relapsed or Refractory Multiple Myeloma

The study is designed as a multicenter, non-randomized, Phase II trial with one treatment arm. A total of 82 patients of both genders and older than 18 years with relapsed/refractory multiple

cyclophosphamide
cell transplantation
alkylating agents
lenalidomide
neutrophil count
  • 2 views
  • 25 Jan, 2021
  • 18 locations
Reduce Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed Multiple Myeloma

This phase II trial studies how well a reduced intensity conditioning regimen after donor stem cell transplant works in treating patients with multiple myeloma that has come back (relapsed

fludarabine
cell transplantation
mycophenolate mofetil
tacrolimus
monoclonal protein
  • 0 views
  • 29 Mar, 2021
  • 1 location