Multiple Myeloma Clinical Trials

A listing of Multiple Myeloma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 77 clinical trials
Study of CB-103 in Adult Patients With Advanced or Metastatic Solid Tumours and Haematological Malignancies

This is a phase I/II, non randomized, open-label, dose escalation study to investigate the safety, tolerability and preliminary efficacy of CB-103.

cb-103
metastatic disease
marginal zone lymphoma
cancer
serum bilirubin
  • 281 views
  • 26 Jan, 2021
  • 12 locations
Descartes-11 in Multiple Myeloma

patients with active multiple myeloma.

measurable disease
bcma
fludarabine
chemotherapy regimen
cyclophosphamide
  • 30 views
  • 17 Feb, 2021
  • 4 locations
ASCT With Nivolumab in Patients With Multiple Myeloma

This is an open-label, single center trial of Autologous Stem Cell Transplantation (ASCT) with nivolumab in multiple myeloma patients to determine the efficacy and safety of ASCT and PD1

measurable disease
melphalan
cell transplantation
colony stimulating factor
granulocyte colony stimulating factor
  • 3 views
  • 24 Mar, 2021
  • 1 location
Isatuximab Bendamustine and Prednisone in Refractory Multiple Myeloma

bendamustine, as well as the established clinical efficacy of bendamustine and isatuximab as single agents for multiple myeloma, the logical next step is to combine isatuximab with bendamustine and prednisone

monoclonal antibodies
prednisone
monoclonal protein
measurable disease
plasmacytoma
  • 0 views
  • 12 Apr, 2021
  • 1 location
First in Human (FIH) Study of REGN5458 in Patients With Relapsed or Refractory Multiple Myeloma

2 dose regimen (RP2DR) of REGN5458 as monotherapy in patients with relapsed or refractory multiple myeloma (MM). In the phase 2 portion of the study: To assess the anti-tumor activity of

immunomodulatory imide drug
immunotherapeutic agent
proteasome inhibitor
refractory multiple myeloma
  • 16 views
  • 12 Jun, 2021
  • 12 locations
ECT-001 (UM171) Expanded Cord Blood Transplant to Treat High-risk Multiple Myeloma

Multiple Myeloma (MM) is a morbid disease associated with a poor outcome and while current therapies with new drugs have improved survival, MM still remains incurable in most patients. The only

graft versus host disease
measurable disease
lenalidomide
bortezomib
melphalan
  • 61 views
  • 05 Feb, 2021
  • 3 locations
Safety and Efficacy of BCMA-Targeted CAR-T Therapy for Relapsed/Refractory Multiple Myeloma

This is a single arm study to evaluate the efficacy and safety of BCMA-targeted CAR-T cells therapy for patients with relapsed/refractory Multiple Myeloma.

bcma
cell transplantation
stem cell transplantation
mental disorders
ejection fraction
  • 0 views
  • 16 Mar, 2021
  • 1 location
BCMA-Targeted CAR-T Cell Therapy for Relapsed/Refractory Multiple Myeloma

This is a single arm study to evaluate the efficacy and safety of BCMA-targeted CAR-T cells therapy for patients with relapsed/refractory Multiple Myeloma.

bcma
cell transplantation
stem cell transplantation
mental disorders
ejection fraction
  • 0 views
  • 14 Mar, 2021
  • 1 location
Melphalan Hydrochloride in Treating Participants With Newly-Diagnosed Multiple Myeloma Undergoing Donor Stem Cell Transplantation

This phase I/II trial studies the side effects and best dose of melphalan hydrochloride in treating participants with newly-diagnosed multiple myeloma who are undergoing a donor stem cell

monoclonal antibodies
carbon monoxide
cancer
cell transplantation
electrophoresis
  • 0 views
  • 26 Jan, 2021
  • 1 location
Study of CAR T-cell Therapy in Acute Myeloid Leukemia and Multiple Myeloma

The purpose of this first-in-man Phase I-IIa study is to evaluate the safety and antitumor activity of autologous CD44v6 CAR T-cells in patients with acute myeloid leukemia (AML) and multiple

  • 0 views
  • 05 Mar, 2021
  • 2 locations