Limb Preservation and Amputation Clinical Trials

A listing of Limb Preservation and Amputation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 17 clinical trials
Investigation of Rifampin to Reduce Pedal Amputations for Osteomyelitis in Diabetics (VA INTREPID)

The purpose of this research study is to determine if rifampin, an antibiotic (a medicine that treats infections), is effective in treating osteomyelitis (infection of the bone) of the foot in diabetic patients. Despite use of powerful antibiotics prescribed over a long period of time, many diabetic patients remain at …

riboflavin
antibiotics
diabetes mellitus
hypoglycemic agents
debridement
  • 660 views
  • 21 Jul, 2022
  • 25 locations
Hand Transplantation

The purpose of this study is to see if an investigational surgery that transfers tissue from a non-living donor to living individual will help restore greater function, appearance, and sensation to the hand and forearm areas of individuals who have suffered traumatic injury to the hand and forearm. This procedure …

hand transplantation
  • 13 views
  • 25 May, 2022
  • 1 location
Early Evaluation of the Introduction of Pre- and Post-operative Psychological and Physiotherapeutic Follow-up in Vascular Surgery in Amputee Patients (EPKIVA)

An amputation represents a real ordeal for the person who will have to overcome the loss of a limb and face long months of rehabilitation. It is most often carried out following arterial insufficiency. As paramedical professionals, we see in our daily practice a physical and psychological suffering for amputee …

  • 4 views
  • 21 Jul, 2022
  • 1 location
Agonist-Antagonist Myoneural Interface for Functional Limb Restoration After Transtibial Amputation

This study involves the functional testing of a new lower extremity prosthesis by healthy, active participants with fully healed transtibial (below knee) amputations. The study design calls for an experimental group of eleven participants who received two agonist-antagonist myoneural interfaces (AMIs) that were surgically constructed during a modified transtibial amputation …

agonist-antagonist
Accepts healthy volunteers
electromyogram
  • 57 views
  • 08 Aug, 2022
  • 1 location
Sensory Responses to Dorsal Root Stimulation

The goal of this project is to characterize the types of sensations that can be evoked via electrical stimulation of the spinal cord and spinal nerves. Patients will be recruited from a local pain clinic, each with a spinal cord stimulation device implanted, to participate in experiments to explore the …

  • 0 views
  • 25 Jul, 2022
  • 1 location
Osseointegrated Human-Machine Gateway (OHMG)

Advanced prosthetic devices are currently controlled by electromyography (EMG) signals generated by patient's stump muscles and recorded by surface electrodes attached on the skin. This way of recordings is often unreliable, inconsistent and leading to high prosthetic abandonment rates for individuals with upper limb amputation. The use of implantable electrodes …

limb amputation
amputation stump
electromyogram
  • 4 views
  • 03 Jun, 2022
  • 1 location
A Comparative Assessment of Transfemoral Prosthetic Sockets

The objective of the proposed work is to enhance understanding of the potential benefits of adjustable sockets and inform clinical decision making.

fitting
limb amputation
  • 0 views
  • 12 Jul, 2022
  • 2 locations
Myoelectric Game Training and Outcomes

The purpose of this study is to evaluate the effects of myo-electric training tools on prosthesis functional outcomes.

Accepts healthy volunteers
  • 14 views
  • 20 Apr, 2022
  • 1 location
Autologous Volar Fibroblast Injection Into the Stump Site of Amputees

This study is a clinical trial testing the safety and efficacy of volar fibroblast (skin cells from the palm or sole) injections for thickening the epidermal (skin) layer at the stump site in people with below the knee amputations. The study will enroll adults seen at Johns Hopkins.

wound care
amputation stump
Accepts healthy volunteers
knee amputation
  • 0 views
  • 05 Jul, 2022
  • 1 location
Clinical Trial Comparing Negative Pressure Wound Therapy and Standard Dry Dressings (BERLYTZ)

Negative pressure dressings are currently widely used in wound management. Their use is gradually being extended to surgical scars. However, studies demonstrating a clear benefit are rare, particularly in terms of postoperative discharge, the need for surgical revision due to prolonged oozing and cost. The aim of this study is …

Accepts healthy volunteers
negative pressure wound therapy
  • 0 views
  • 03 Jun, 2022
  • 1 location