Limb Preservation and Amputation Clinical Trials

A listing of Limb Preservation and Amputation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 36 clinical trials
Investigation of Rifampin to Reduce Pedal Amputations for Osteomyelitis in Diabetics (VA INTREPID)

The purpose of this research study is to determine if rifampin, an antibiotic (a medicine that treats infections), is effective in treating osteomyelitis (infection of the bone) of the foot in diabetic patients. Despite use of powerful antibiotics prescribed over a long period of time, many diabetic patients remain at …

diabetic foot
oral hypoglycemic
glycosylated hemoglobin
  • 21 Jul, 2022
  • 25 locations
Feasibility of Sensory Feedback for Lower Limb Amputees

The purpose of this study is to evaluate the effectiveness of providing sensation of the missing limb by applying small electrical current directly to the remaining sensory nerves via implanted stimulating electrodes. These small electrical currents cause the nerves to generate signals that are then transferred to your brain just …

nerve conduction
  • 26 Feb, 2022
  • 1 location
A Novel Approach to Upper Extremity Amputation to Augment Volitional Control and Restore Proprioception

The hypothesis of this research protocol is that the investigators will be able to redesign the manner in which upper limb amputations are performed so as to enable volitional control of next generation prosthetic devices and restore sensation and proprioception to the amputated limb. The investigators will test this hypothesis …

Accepts healthy volunteers
  • 10 Feb, 2022
  • 2 locations
Intuitive Control of a Hybrid Prosthetic Leg During Ambulation

The objective of this research is to determine the clinical benefits of an innovative and lightweight powered leg controlled using our intent recognition framework in laboratory and community environments.

limb amputation
amputation of the lower limb
  • 14 Feb, 2022
  • 1 location
AMI Construction in Lower Extremity Residual Limbs

This study will involve the development of a novel approach to lower extremity residual limb surgical revision that offers the promise of augmenting volitional motor control, restore proprioception and reverse atrophy

amputation stump
Accepts healthy volunteers
  • 04 Mar, 2022
  • 1 location
Hybrid Pump Technology (HIPPI)

Prostheses can be suspended from the amputated limb using a variety of techniques, such as straps and suction. Suspending the prosthesis by creating a vacuum between the prosthetic socket and limb using a pump has benefits over other techniques including improved limb health and mobility. A new pump design will …

  • 16 Mar, 2022
  • 1 location
Personalized Mobility Interventions Using Smart Sensor Resources for Lower-Limb Prosthesis Users

The goal of this research is to analyze data from smartphone-based and wearable sensors, using advanced machine-learning and data-mining techniques, and to combine this information with performance-based measures, participant-reported measures, and structured interviews to create a clinical toolbox to (i) identify individuals who exhibit reduced prosthesis use (compared to expected …

limb amputation
amputation of the lower limb
  • 05 Apr, 2022
  • 3 locations
Transfemoral Socket Design and Muscle Function

The objective of this pilot research project is to evaluate the effect of prosthetic socket design on amputated limb hip muscle strength and endurance in Service members, Veterans, and civilians who use above-the-knee prostheses. Traditional above-the-knee socket designs provide pelvic support that interferes with hip motion. They may also reduce …

  • 13 Mar, 2021
  • 1 location
Safety and Effectiveness of Electronically Controlled Prosthetic Ankle

In this study, we aim to compare the three types of prosthetic limbs: the passive prosthetic limb that the patients have been using so far, the 'RoFT', a prosthetic limb developed by the Korea Institute of Machinery & Materials, and the Meridium of Ottobock in terms of safety and effectiveness.

  • 27 Jan, 2021
  • 1 location
Hand Transplantation

The purpose of this study is to see if an investigational surgery that transfers tissue from a non-living donor to living individual will help restore greater function, appearance, and sensation to the hand and forearm areas of individuals who have suffered traumatic injury to the hand and forearm. This procedure …

hand transplantation
  • 25 May, 2022
  • 1 location