Limb Preservation and Amputation Clinical Trials

A listing of Limb Preservation and Amputation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 51 clinical trials
Investigation of Rifampin to Reduce Pedal Amputations for Osteomyelitis in Diabetics

The purpose of this research study is to determine if rifampin, an antibiotic (a medicine that treats infections), is effective in treating osteomyelitis (infection of the bone) of the foot in diabetic patients. Despite use of powerful antibiotics prescribed over a long period of time, many diabetic patients remain at …

diabetes
glycosylated hemoglobin
diabetes mellitus
rifampin
hemoglobin a1c
  • 513 views
  • 29 Jul, 2021
  • 30 locations
Feasibility of Sensory Feedback for Lower Limb Amputees

The purpose of this study is to evaluate the effectiveness of providing sensation of the missing limb by applying small electrical current directly to the remaining sensory nerves via implanted stimulating electrodes. These small electrical currents cause the nerves to generate signals that are then transferred to your brain just …

fitting
nerve conduction
  • 1 views
  • 26 Jan, 2021
  • 1 location
e-OPRA Implant System for Lower Limb Amputees

The e-OPRA Implant System, is a further development of the OPRA (Osseointegrated Prostheses for the Rehabilitation of Amputees) Implant System, approved under HDE (Humanitarian Device Exemption) H080004. The e-OPRA Implant system is an implant system for direct skeletal anchorage of amputation prostheses. The added feature in the e-OPRA Implant system, …

exhausted
  • 2 views
  • 23 Jan, 2021
  • 1 location
A Novel Approach to Upper Extremity Amputation to Augment Volitional Control and Restore Proprioception

The hypothesis of this research protocol is that the investigators will be able to redesign the manner in which upper limb amputations are performed so as to enable volitional control of next generation prosthetic devices and restore sensation and proprioception to the amputated limb. The investigators will test this hypothesis …

arthritis
agonist-antagonist
  • 5 views
  • 10 May, 2021
  • 2 locations
A Test-Drive Strategy for the Prescription of Prosthetic Feet for People With Leg Amputations

Objective/Hypotheses and Specific Aims: The primary aim of this proposal is to determine whether a PFE can be used to predict foot preference and mobility outcomes with corresponding commercial prosthetic feet in people with a unilateral transtibial amputation (TTA). Secondarily, the investigators aim to determine whether a brief trial of …

fitting
  • 142 views
  • 10 Jun, 2021
  • 3 locations
Agonist-Antagonist Myoneural Interface for Functional Limb Restoration After Transtibial Amputation

This study involves the functional testing of a new lower extremity prosthesis by healthy, active participants with fully healed transtibial (below knee) amputations. The study design calls for an experimental group of eleven participants who received two agonist-antagonist myoneural interfaces (AMIs) that were surgically constructed during a modified transtibial amputation …

agonist-antagonist
electromyogram
  • 50 views
  • 19 Jul, 2021
  • 1 location
Daily Socket Comfort in Transtibial Amputee With an Active Vacuum Suspension System

The aim of this study is to evaluate the contribution of the vacuum suspension system in an ecological environment on the fitting's comfort compared to the vacuum suspension system inactive system in a multicenter prospective, randomized, double-blind, multiple N-of-1 trial. In order to assess the therapeutic effect of the vacuum …

  • 0 views
  • 25 Mar, 2021
  • 3 locations
Early Evaluation of the Introduction of Pre- and Post-operative Psychological and Physiotherapeutic Follow-up in Vascular Surgery in Amputee Patients

An amputation represents a real ordeal for the person who will have to overcome the loss of a limb and face long months of rehabilitation. It is most often carried out following arterial insufficiency. As paramedical professionals, we see in our daily practice a physical and psychological suffering for amputee …

  • 0 views
  • 22 Apr, 2021
  • 1 location
Personalized Mobility Interventions Using Smart Sensor Resources for Lower-Limb Prosthesis Users

The goal of this research is to analyze data from smartphone-based and wearable sensors, using advanced machine-learning and data-mining techniques, and to combine this information with performance-based measures, participant-reported measures, and structured interviews to create a clinical toolbox to (i) identify individuals who exhibit reduced prosthesis use (compared to expected …

  • 0 views
  • 14 Apr, 2021
  • 3 locations
Transfemoral Socket Design and Muscle Function

The objective of this pilot research project is to evaluate the effect of prosthetic socket design on amputated limb hip muscle strength and endurance in Service members, Veterans, and civilians who use above-the-knee prostheses. Traditional above-the-knee socket designs provide pelvic support that interferes with hip motion. They may also reduce …

  • 0 views
  • 13 Mar, 2021
  • 1 location