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Bipolar Disorder Clinical Trials

A listing of Bipolar Disorder medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (226) clinical trials

Patients are needed to participate in a clinical research study for the treatment of Pediatric Bipolar Disorder

To address the urgent therapeutic needs of children and adolescents ages 4-17 with pediatric bipolar disorder, we have designed a series of clinical trials aimed at evaluating critical components of the treatment needs of this under-served and under-researched population. This approach will allow us to provide a full complement of ...

Phase N/A

The Gut Microbiota of Bipolar and Depression

Background: MDD (Major Depressive disorder) and BD (Bipolar disorder), whose specific pathogenesis is still unclear, are both a multi-factorial disease being caused by biological, psychological and social factors. Accumulating evidence suggests that gut microbiota play an important role in brain functions and in the pathogenesis of neuropsychiatric diseases, such as ...

Phase N/A

Rostral Dorsal Cingulum Bundle Connectivity in Patients With Bipolar Disorder Type I

The overall goal of this study is to employ diffusion-weighted imaging (DWI) and tractography to investigate differences in connectivity in the rostral dorsal cingulum bundle (CB) in patients with bipolar disorder type I (BDI) compared to matched controls, and to utilize this information to determine if high-frequency deep brain stimulation ...

Phase N/A

Treating Insulin Resistance as a Strategy to Improve Outcome in Refractory Bipolar Disorder

This will be a 26-week randomized, double-blind, parallel group prospective study of the efficacy of metformin as add-on treatment in patients with insulin resistance ( IR) and non-remitting bipolar illness, conducted over three years. The investigators will compare the effects of metformin versus placebo on outcome in each patient, while ...

Phase

Minocycline and Celecoxib as Adjunctive Treatments of Bipolar Depression

Bipolar disorder is a leading cause of disability worldwide. A high proportion of patients with bipolar disorder experience persistent depressive symptoms that do not respond to standard drug treatments. Recent evidence has suggested that anti-inflammatory treatment may reduce depressive symptoms. Minocycline is a tetracycline antibiotic with good central nervous system ...

Phase

Family Focused Therapy for Teens at Risk for Bipolar Disorder

Children of parents with bipolar disorder (BD) have increased risk of developing BD themselves. BD in youth is associated with increased risk for suicidality, psychosis, substance abuse and compromised psychosocial functioning. In addition, offspring of parents with BD have an increased vulnerability for developing other psychopathology (e.g. major depression). At ...

Phase N/A

Validation of a Cognitive Remediation Program for Bipolar Disorders

This study evaluates the effect of a new cognitive remediation program designed for patients suffering from a bipolar disorder, on cognitive functions, psychosocial functioning and neural processes. In this double-blind (patient, outcomes assessor) controlled randomized trial the investigators compare patients receiving the ECo program for bipolar disorders, to patients benefiting ...

Phase N/A

Trehalose as add-on Therapy in Bipolar Depression

This is an investigator-initiated parallel group pilot study. All patients will give a signed informed consent prior to initiation of any study procedure. Study setting: This unicentric pilot study will be carried out at the Bipolar Disorder Programme of the Hospital Clinic, University of Barcelona. Over 700 Bipolar Disorder patients ...

Phase

Efficacy of an Innovative E-neurocognitive Module for Bipolar Disorder

This is a randomized clinical study, rater-blind, placebo-controlled stratified by age, sex and educational level to assess the efficacy of a new program, an adjunctive e-neurocognitive module, to functional remediation intervention. The primary outcome measure will be the improvement in global psychosocial functioning measured blindly as the mean change in ...

Phase N/A

Representations and Strategies for Recovery

Elaboration of a semi directed grid (exploratory phase) Collection of individual narratives Data analysis, according to IPA method (interpretative phenomenological analysis) On the basis of individual narratives On the basis of a focus group 4. Publication of results

Phase N/A