Liver Cancer Clinical Trials

A listing of Liver Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 734 clinical trials
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Cabozantinib in Hepatocellular Carcinoma

There have been lack of clinical studies on the role of drug treatment in patients who develop progressive disease with immune checkpoint inhibitors. Amongst HCC patients who become intolerant or refractory to sorafenib, cabozantinib has been shown by phase III clinical trial (CELESTIAL) to prolong the overall survival of patients, …

  • 0 views
  • 27 Jan, 2021
  • 2 locations
None
CGX1321 in Subjects With Advanced Solid Tumors and CGX1321 With Pembrolizumab in Subjects With Advanced GI Tumors (Keynote 596)

This is a multicenter, open-label study conducted in two phases: Phase 1 consisting of a CGX1321 Single Agent Dose Escalation Phase in solid tumors, CGX1321 Single Agent Dose Expansion Phase in GI tumors and Roll-over Cohort of CGX1321 and pembrolizumab in subjects who have progressed on single agent CGX1321 and …

measurable disease
pembrolizumab
solid tumour
  • 0 views
  • 26 Jan, 2021
  • 8 locations
None
Effect of Polymorphisms in the IL-1 Gene Complex on the Development of Chronic Hepatitis and Hepatocellular Carcinoma

The purpose of this study is to determine the effect of polymorphisms in the IL-1 gene complex on the development of chronic hepatitis and hepatocellular carcinoma.

hepatitis
hepatocellular carcinoma
  • 3 views
  • 07 Nov, 2020
  • 1 location
None
The Risk of Exacerbation of Chronic Hepatitis B After Percutaneous Radiofrequency Ablation of Hepatocellular Carcinoma

This study aim to find out the risk of exacerbation of chronic hepatitis B after percutaneous radiofrequency ablation (RFA) or hepatectomy for HCC, and it's effect to treatment outcome.

hepatitis
encephalopathy
hepatocellular carcinoma
radiofrequency ablation
ascites
  • 4 views
  • 07 Nov, 2020
  • 1 location
None
Efficacy of Antiviral Therapy After Radical Resection for Hepatitis B Virus-Related Hepatocellular Carcinoma

Most hepatocellular carcinomas are associated with hepatitis B virus, it is hypothesized that anti-viral treatment may be helpful in treating HBV-related hepatocellular carcinoma.

hepatitis
hepatitis b surface antigen
antiviral drugs
entecavir
lamivudine
  • 14 views
  • 07 Nov, 2020
  • 1 location
None
Case-Control Study of the Glycotest HCC Panel vs AFP for the Detection of Early-stage Hepatocellular Carcinoma

Clinical guidelines (AASLD) recommend the use of abdominal ultrasound (US) for surveillance testing for the early detection of Hepatocellular Carcinoma (HCC). The serum protein biomarker alpha-fetoprotein (AFP) is commonly used to augment US but its use alone is not recommended by clinical guidelines. Despite evidence that HCC surveillance improves early …

alpha fetoprotein
hepatitis
liver disease
carcinoma
hepatocellular carcinoma
  • 1 views
  • 26 Jan, 2021
  • 18 locations
None
RFA Using Combined Bipolar and Monopolar Energy Deliver With Twin Cooled-Wet Electrodes

In this study, a dual / Twin Cooled-wet electrode was used to perform RFA therapy on residual tumors after transarterial chemo-embolization and to find out the therapeutic results. The primary endpoint is the 12-month local recurrence rate, and the secondary endpoint is the survival rate, disease-free survival rate, actual procedure …

metastasis
cancer
  • 0 views
  • 28 Mar, 2021
None
RFA Using Gradual RF Energy Delivery Mode With Octopus Electrodes

The investigators intend to perform RFA therapy on HCC less than 4 cm in size using octopus electrode, double alternating unipolar high-frequency transmission mode and gradual high-frequency energy loading mode, and to find out the therapeutic results. The primary evaluation variable is the ideal technical success rate for securing a …

cirrhosis
hepatitis
  • 0 views
  • 28 Mar, 2021
  • 1 location
None
Identification of Biomarkers Associated With Human Hepatocellular Carcinoma by SELDI

Hepatocellular carcinoma (HCC) has been the leading cause of cancer death in Taiwan. Though Alpha-fetoprotein (AFP) and des-γ-carboxy prothrombin(DCP) are used as the tumor markers for diagnosis of HCCs. Thus, these two markers are not good enough for the early detection of small HCCs. To improve the survival, further investigations …

alpha fetoprotein
alpha-fetoprotein
hepatitis
hepatocellular carcinoma
prothrombin
  • 3 views
  • 07 Nov, 2020
  • 1 location
None
A Study to Evaluate the Efficacy and Safety of Anti-PD-1 Antibody AK105 in Patients With Selected Advanced Solid Tumors

This is a multi-center, multi-cohort, open-label, phase Ib/II study to evaluate the efficacy, safety, PK characteristics, immunogenicity and potential biomarkers of AK105 monotherapy in the patients with selected advanced solid tumors.

measurable disease
solid tumor
advanced malignant solid tumor
  • 2 views
  • 23 Jan, 2021
  • 1 location