Liver Cancer Clinical Trials

A listing of Liver Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 740 clinical trials
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Efficacy and Safety of Cabozantinib in Patients With Hepatocellular Carcinoma

This is an open-label, single-center, Phase II trial designed to estimate in terms of PFS the efficacy of cabozantinib, given as second- or third- line treatment in HCC patients that progress on or are intolerant to immune checkpoint inhibitors, including anti-PD-1 and anti-PD-L1 antibodies.

neutrophil count
antiviral therapy
hepatitis
radiofrequency ablation
antiviral drugs
  • 0 views
  • 24 Jan, 2021
  • 1 location
None
Characterizing Disease Biology Treatment and Toxicity in Older Adults With Hepatocellular Carcinoma

This is an observational, prospective cohort study that will recruit a diverse sample of 84 participants with newly diagnosed with unresectable, advanced hepatocellular carcinoma (HCC) at the UT Health Cancer Center in San Antonio. This study uses geriatric assessment tools with participants 65 years and older and collects adverse events …

cancer
  • 0 views
  • 26 Jan, 2021
  • 1 location
None
Sequential TransArterial Chemoembolization and Stereotactic RadioTherapy With ImmunoTherapy for Downstaging Hepatocellular Carcinoma for Hepatectomy

This study is a prospective phase II, single arm mono-institutional study conducted in Queen Mary Hospital (Hong Kong) assessing the efficacy and safety of the sequential administration of trans-arterial chemo-embolization (TACE) and stereotactic body radiotherapy (SBRT) with an immune checkpoint inhibitor in hepatocellular carcinoma (HCC) patients.

antiviral therapy
systemic therapy
hepatitis
antiviral drugs
measurable disease
  • 0 views
  • 23 Jan, 2021
  • 1 location
None
Pembrolizumab in Hepatocellular Carcinoma

This is a single-arm Phase II trial of pembrolizumab in patients with hepatitis B virus-related hepatocellular carcinoma with parallel study on baseline and serial change in the immune environment. Subjects should have a confirmed diagnosis of HCC (in accordance with the AASLD guideline) and confirmed chronic infection with hepatitis B …

neutrophil count
antiviral therapy
hepatitis
antiviral drugs
prothrombin
  • 1 views
  • 28 Oct, 2021
  • 1 location
None
Hepatocellular Carcinoma on Cirrhosis With Child A/B7 and Hepatic Intra Arterial Injection of Idarubicin/Lipiodol Emulsion

The investigators propose in this trial to test a hepatic chemotherapy, consisting of the hepatic intra-arterial injection Idarubicin, emulsified with Lipiodol, lipid vector, without embolization in the treatment of non-metastatic, unresectable hepatocellular carcinoma on cirrhosis with Child-Pugh A/B7.

neutrophil count
unresectable hepatocellular carcinoma
radioembolization
arterial embolization
cirrhosis
  • 7 views
  • 23 Jan, 2021
  • 3 locations
None
Microwave Ablation Versus Liver Resection For Early Hepatocellular Carcinoma in Patients With Borderline Liver Function

We propose a randomized controlled study to compare the treatment efficacy of microwave ablation to liver resection for hepatocellular carcinoma (HCC) in patients with borderline liver function.

hepatectomy
metastasis
  • 0 views
  • 11 Aug, 2021
  • 1 location
None
Combi-elastography Assessment of HCC Recurrence After Thermal Ablation Multi-center Study

Combined F index, A index,ATT index and spleen stiffness to predict tumor recurrence in different liver settings after thermal ablation of HCC.

  • 0 views
  • 02 Feb, 2021
  • 1 location
None
Transarterial Embolization Alone Versus Drug-Eluting Beads Chemoembolization for Hepatocellular Carcinoma

Developed in Japan in the 1980s, TACE became the most frequent treatment for unresectable hepatocellular carcinoma (HCC) in patients with preserved hepatic function after 2002, when two radiochemotherapies (RCTs) showed survival benefits for HCC patients who underwent conventional Lipiodol-based TACE (cTACE). Nowadays, nearly half of HCC patients undergo this procedure …

  • 0 views
  • 25 Mar, 2021
  • 1 location
None
A Dose Escalation Study of LNA-i-Mir-221 for Cancer Treatment

The LNA-i-miR-221 Phase I trial has been designed as a monocentric open label dose escalation study which received written approval by the Competent Authority and independent Ethics Committee (IEC). LNA-i-miR-221 will be investigated for safety and tolerability in patients, men and women age 18 yrs, affected by Refractory-MM and advanced …

  • 0 views
  • 28 Mar, 2021
  • 1 location
None
Atezolizumab Plus Bevacizumab With HCC and HBV Infection

This is a single-arm clinical trial. The main objective is to determine the efficacy of atezolizumab+bevacizumab therapy in patients with advanced hepatocellular carcinoma and with chronic hepatitis B virus infection. All eligible patients will receive atezolizumab + bevacizumab therapy.

  • 0 views
  • 04 Apr, 2021
  • 8 locations