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Aging Clinical Trials

A listing of Aging medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (875) clinical trials

Role of Sleep on Motor Learning in Parkinson's Disease and Healthy Older Adults

PwPD often fail to retain training effects via the process of motor memory consolidation, by which newly acquired skills transform intro robust and long-lasting motor memories without further practice. Compromised consolidation leads to an inevitable deterioration of daily functioning while hindering the prolonged effects of rehabilitation even in the early ...

Phase N/A

Macular Edema Ranibizumab v. Intravitreal Anti-inflammatory Therapy Trial

Macular edema (ME) is the most common structural complication and cause of visual impairment and legal blindness in uveitis patients. Traditional approaches to the treatment of uveitic ME have included the use of regional corticosteroid therapy, delivered periocularly, including posterior sub-Tenon's and orbital floor injections, or via the intravitreal route. ...


Impact of HIV-1 and Aging on Mucosal Vaccine Responses

The purpose of this study is to learn more about both HIV-1 infection and advancing age, alone and in combination, and their association with increased risk of serious infection and impaired response to the Prevnar 13 vaccine.


Pfs230D1M-EPA/AS01 Vaccine a Transmission Blocking Vaccine Against Plasmodium Falciparum in an Age De-Escalation Trial of Children and a Family Compound Trial in Mali

A vaccine to interrupt malaria transmission (VIMT), targeting disruption of both human and mosquito transmission, would be a valuable tool for local elimination or eradication of this disease. One strategy to design a VIMT is using components that block transmission of malaria to mosquitoes, such as Pfs230. Pfs230, a surface ...


The Northwestern University Two-Generation Study of Parent and Child Human Capital Advancement

The Northwestern University Two-Generation Study (NU2Gen) of Parent and Child Human Capital Advancement is funded through Community Action Project of Tulsa County's (CAP Tulsa) Health Profession Opportunity Grant (HPOG II) from the Administration for Children and Families and through the HPOG II University Partnership grant. The federal awards support the ...

Phase N/A

A Safety Study of 2 Formulations of GlaxoSmithKline Biologicals' (GSK's) Human Rotavirus (HRV) Vaccine in Healthy Infants of Age 6-12 Weeks

The purpose of this study is to complete the total safety database size for GlaxoSmithKline Biologicals' (GSK's) human rotavirus (HRV) vaccine (ROTARIX) across the Porcine circovirus (PCV)-free development plan. This study will use a purposely selected lot for PCV-free liquid HRV vaccine that is in the upper range of the ...


Activate For Life: mHealth Intervention To Address Pain And Fatigue In Low-income Older Adults Aging In Place

The Overall Aim of the present proposal is to evaluate the feasibility of an integrated mind-body intervention, Activate for Life, to improve overall physical activity and mental health and reduce pain and fatigue, resulting in increased likelihood of Aging in Place. Both subjective self-report (i.e., NIH PROMIS measures of pain, ...

Phase N/A

A Study to Evaluate the Safety and Efficacy of Upadacitinib in Participants With Giant Cell Arteritis

This study consists of two periods. The objective of Period 1 is to evaluate the efficacy of upadacitinib in combination with a 26-week corticosteroid (CS) taper regimen compared to placebo in combination with a 52-week CS taper regimen, as measured by the proportion of participants in sustained remission at Week ...


Treatment for Elderly Fit Newly Diagnosed Multiple Myeloma Patients Aged Between 65 and 80 Years

After 18 cycles, patients not having received daratumumab before (arm 1 and 2a), will receive consolidation with 4 cycles of Lenalidomida-dexamethasone at low dose-DARATUMUMAB. At this point (after 22 months on treatment for the VMP-Rd and KRd arm and after 18 months of the Carfilzomib-lenalidomida-dexametasona-DARATUMUMAB arm) patients will be stratified ...