Search Medical Condition
Please enter condition
Please choose location

Aging Clinical Trials

A listing of Aging medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (47) clinical trials

Human Mesenchymal Stem Cells (LMSCs) on Vaccine-Specific Antibody- Response in Subjects With Aging Frailty

A pilot phase will consist of a 3 subject safety run-in, followed by 20 subject randomized phase to evaluate influenza vaccine response at 1 week and 4 weeks post infusion of LMSCs. This will be followed by a double-blinded, randomized, placebo-controlled phase.

Phase

Effects of Exercise Intervention on Aging-related Motor Decline

The U.S. Census reports over 14 million U.S. Veterans (>63%) are beyond mid-life (>55 years). Declines in upper extremity motor performance respective of strength and dexterity are well documented within this age cohor). Recent cross-sectional research has discovered that aging related motor deficits may be influenced by a loss of ...

Phase N/A

Evaluating Hearing Aid Service Delivery Models

The purpose of this study is to compare the outcomes for two different hearing-aid delivery models. In one model, the audiologist selects and fits the hearing aid and, in the other model, the consumer does this directly.

Phase N/A

Predictors of Cognitive Decline in Normal Aging

Studies of normal aging and mild cognitive impairment (MCI) show that loss of neurons and reduction in size of the hippocampal part of the brain predict a person's conversion from MCI to Alzheimer's disease (AD). Increases in tangle-related abnormal tau proteins, specifically P-tau231, also appear to be related. This study ...

Phase N/A

Retinol-induced Dermatitis in Aged Skin

Topical therapy with retinoids is the only proven medical therapy for aged/photoaged human skin. However, topical therapy with retinoids often result in unwanted cutaneous dermatitis, including erythema and scaling. The reseachers intend to investigate the dose, frequency of use, and time dependence of topical retinol-induced dermatitis. The researchers intend to ...

Phase N/A

AllogeneiC Human Mesenchymal Stem Cells (hMSC) in Patients With Aging FRAilTy Via IntravenoUS Delivery.

A Pilot Phase will be performed to test the safety of dose and volume escalation of cells administered via peripheral intravenous infusion. The randomized portion of the study will be conducted after a full review of the safety data from the Pilot Phase by the data safety monitoring board. PILOT ...

Phase

Prevalence and Post-surgical Outcomes of CARdiac Wild-type TransthyrEtin amyloidoSIs in Elderly Patients With Aortic steNosis Referred for Valvular Replacement.

Cardiovascular diseases remain the major cause of mortality and morbidity in industrialised countries. Their prevalence increases steeply as consequence of the aging of the population in these countries. Curiously, cardiovascular and neurodegenerative diseases share common aging pathological pathways involving abnormal accumulation of insoluble amyloid proteins in the extracellular matrix disrupting ...

Phase N/A

Plasticity-based Adaptive Cognitive Remediation for Alzheimer Disease

The normal aging has a devastating effect on our cognitive ability to learn and remember, on the speed with which the investigators process information, and on our ability to reason. By 2050, nearly 14 million individuals in the US will be living with Alzheimer's disease (AD), up from 5 million ...

Phase N/A

Lake Nona Life Project

The Lake Nona Life Project is a community health and wellness research project of the Lake Nona Institute (LNI), carried out by the Lake Nona Medical City Residents and Partners (the Researchers), and sponsored by Johnson & Johnson Health and Wellness Solutions (JJ HWS). The project is designed to study ...

Phase N/A

Omics4Aging: Stratification of Frailty Population

This exploratory study will investigate ways to better characterize the frailty phenotype by a combination of i) geriatric assessment (here only: frailty criteria according to Fried), ii) clinical surrogate markers (including those of inflammation), iii) body composition, iv) nutritional profiling, v) metabolite profiling using a metabolomics approaches.

Phase N/A