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Aging Clinical Trials

A listing of Aging medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found (84) clinical trials

Baltimore Longitudinal Study of Aging

The Baltimore Longitudinal Study of Aging (BLSA) is the NIA s major clinical research program in human aging that has been conducted in Baltimore since 1958. The study population is a series of healthy volunteers of different ages followed indefinitely with serial evaluations over time. The major aim of the …

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Blood-Brain Barrier Disruption in People With White Matter Hyperintensities Who Have Had a Stroke

Objective: To follow a cohort of stroke patients with white matter hyperintensities (WMH), using MRI, and thereby track the natural history of changes in blood-brain barrier (BBB) disruption. By establishing a better understanding of the relationship between the presence of BBB disruption and WMH progression, we hope to identify BBB …

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Using TMS to Increase Executive Function in Older Adults

Cognitive decline and dementia have become important public health issues in our time as medical science has increased lifespan and our society becomes progressively older. A great deal of the cognitive decline due to aging can be explained by decline in working memory (WM), a mental function central to cognition …

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Outcomes and Prognostic Factors in COVID-19

Data are collected regarding: Pre-Admission life conditions with Frailty (CFS, optional: KATZ ADL); Comorbidities; ICU-Admission (e.g. SOFA), ICU-Treatment, Survival Data are collected electronically through an e-CRF and with baseline documentation of the ICU. The database is located in Denmark, at the Department of Epidemiology, University of Aarhus. Each ICU will …

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Non-exercise Physical Activity Intervention

Physical inactivity is prevalent in older adults and poses a risk factor for the development of type 2 diabetes. The aim of this pilot study was to examine the effect of non-exercise physical activity using a standing desk on clinical variables in older adults with type 2 diabetes.

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Aerobic Exercise and Cerebrovascular Function

To address the growing healthcare challenges of an aging Veteran population it is critical to understand effective rehabilitation techniques that mitigate age-related co-morbidity and improve quality of life. To date, exercise is one of a few proven interventions that attenuates age-related declines in brain health and function. A consistent but …

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Eating Habits and Lifestyle Profile of an Italian Aging Cohort

The study concerns the elderly population of the Milan Metropolitan Area. The aim is to identify and interpret the nutritional needs of the target population and thus implement the quality of life and the nutritional status of citizens through the evaluation of the dietary habits, health status and lifestyle of …

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Sodium-glucose Co Transporter 2 (sGLT2) Inhibitor and Endogenous Ketone Production

Objective and Specific Aims: The objective of this proof-of-concept study is to demonstrate in non-diabetic men and women age > 55 years that a sGLT2 inhibitor will increase ketone bodies and metabolites used for gluconeogenesis. We also hypothesize that sGLT2 inhibitor (empagliflozin) will increase circulating glucagon and fatty acids, decrease …

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Bingocize: A Novel Mobile Application for Older Adult Health

Health-promoting interventions designed to improve physical and mental fitness can help reduce health care costs; they can also help maintain, or even improve, older adults' quality of life. However, getting older adults to adhere to health-promoting exercise interventions remains difficult because such programs are often perceived as being time-consuming, painful, …

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Influence of Brain Oscillation-Dependent TMS on Motor Function

Study Description: We will study if corticospinal excitability (primary outcome measure) varies across different sensorimotor alpha EEG waveform oscillation phases in healthy older adults and chronic stroke patients. Sensorimotor cortical neuronal spiking is highest at sensorimotor alpha oscillation troughs and lowest at sensorimotor alpha oscillation peaks, suggesting that cortical excitability …

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