Mesothelioma Clinical Trials

A listing of Mesothelioma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 42 clinical trials
A Study of TAK-500 With or Without Pembrolizumab in Adults With Select Locally Advanced or Metastatic Solid Tumors

This study is about TAK-500, given either alone or with pembrolizumab, in adults with select locally advanced or metastatic solid tumors. The aims of the study are: to assess the safety profile of TAK-500 when given alone and when given with pembrolizumab. to assess the effects of TAK-500, when given …

cancer
carcinoma
monoclonal antibodies
platelet count
growth factor
  • 12 views
  • 04 Oct, 2022
  • 1 location
A Phase 1, Open-Label, Multi-Center, Dose Escalation and Expansion Study of HFB200301 (TNFR2 Agonist Antibody) in Adult Patients With Advanced Solid Tumors

The purpose of this study is to test the safety and tolerability of HFB200301 in patients with advanced cancers. There are two parts in this study. During the escalation part, groups of participants will receive increasing doses until a safe and tolerable dose of HFB200301 is determined. During the expansion …

braf v600e mutation
carcinoma
systemic therapy
measurable disease
cancer
  • 0 views
  • 21 Oct, 2022
  • 10 locations
A Study of NX-1607 in Adults With Advanced Malignancies

This is a first-in-human Phase 1a/1b multicenter, open-label oncology study designed to evaluate the safety and anti-cancer activity of NX-1607 in patients with advanced malignancies.

growth factors
carcinoma
systemic therapy
measurable disease
fallopian tube
  • 0 views
  • 10 Apr, 2023
  • 7 locations
Improving Patient and Caregiver Understanding of Risks and Benefits of Immunotherapy for Advanced Cancer (UPLIFT)

The purpose of this study is to refine and pilot test educational material developed to educate and support patients receiving immunotherapy for advanced cancer. The intervention is an educational video and question prompt list (QPL) to promote communication between patients, caregivers, and the oncology team about the risks and benefits …

Accepts healthy volunteers
  • 0 views
  • 07 Oct, 2022
  • 1 location
Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma and Other Mesothelin Expressing Cancers

Background Malignant mesothelioma is a malignancy arising from the mesothelial cells of the pleura, peritoneum, pericardium, or tunica vaginalis.

malignant mesothelioma
carcinoma
cancer
pleural mesothelioma
cell cultures
  • 15 views
  • 27 Oct, 2022
  • 1 location
Long Term Follow-up of Mesothelioma Patients and Their Family Members With Germline Mutations in BAP1 and Other Genes

in the BAP1 gene can cause mesothelioma and other cancers. Researchers want to study people with germline mutations of BAP1 and other genes known to cause cancer. Objective

blood test
skin lesions
cancer
BAP1
  • 5 views
  • 21 Oct, 2022
  • 1 location
Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome

. Germline mutations in a gene called BAP1 are linked to the development of mesothelioma and other cancers. Researchers want to follow people with these mutations to learn more. Objective

thoracoscopy
cancer
BAP1
Accepts healthy volunteers
  • 0 views
  • 28 Oct, 2022
  • 1 location
Evaluation of Cell Changes in Blood and Tissue in Cancers of the Lung, Esophagus and Lung Lining

Background Chromatin is is the structural building block of a chromosome. It is found inside the nucleus of the cell and consists of a complex of DNA and protein. Cancers of the lung, pleura (lung lining) and esophagus show profound changes in chromatin structure that may affect the course of …

esophagus cancer
bronchoscopy
cancer
carcinoma
metastasis
  • 139 views
  • 10 Apr, 2023
  • 1 location
Rapid Autopsy and Procurement of Cancer Tissue

Background Individuals with cancer of the lung, chest cavity, ovary, or bladder, as well as patients who have been treated with adoptive cell therapy unfortunately commonly succumb to their disease. Some agree to donate their bodies to cancer research that may help the medical community better understand these diseases. Studies …

cancer
carcinoma
incurable disease
stage iv non-small cell lung cancer
thymoma
  • 45 views
  • 11 Apr, 2023
  • 1 location
Frequency and Clinical Phenotype of BAP1 Hereditary Predisposition Syndrome

BAP1 mutation such as mesothelioma, renal cell carcinoma, cholangiocarcinoma, hepatocellular carcinoma, meningioma and basal cell carcinoma.

carcinoma
cancer
BAP-1
BAP1
Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location