Mesothelioma Clinical Trials

A listing of Mesothelioma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 36 clinical trials
A Phase 1/2 Study of CPI-0209 in Patients With Advanced Solid Tumors and Lymphomas

First-in-human, open-label, sequential dose escalation and expansion study of CPI-0209 in patients with advanced solid tumors and lymphomas. CPI-0209 is a small molecule inhibitor of EZH2.

anaplastic large cell lymphoma
measurable disease
solid tumour
brentuximab
renal function
  • 1 views
  • 22 Oct, 2022
  • 14 locations
Phase 1/2 Study of MRTX1719 in Solid Tumors With MTAP Deletion

This is a Phase 1/2, open-label, multicenter, study of the safety, tolerability, PK, PD, and anti-tumor activity of MRTX1719 patients with advanced, unresectable or metastatic solid tumor malignancy with homozygous deletion of the MTAP gene.

measurable disease
  • 0 views
  • 04 Oct, 2022
  • 4 locations
Phase I/II Evaluation of Oral Decitabine/Tetrahydrouridine as Epigenetic Priming for Pembrolizumab Immune Checkpoint Blockade in Inoperable Locally Advanced or Metastatic Non-Small Cell Lung Cancers, Esophageal Carcinomas, or Pleural Mesotheliomas

Background Non-small cell lung cancer (NSCLC) is the most common type of lung cancer. Lung cancer is the leading cause of cancer-related death in the United States. Most people with lung cancer are already in the advanced stages of the disease by the time they see a doctor. Researchers want …

EGFR
measurable disease
carcinoma
total bilirubin
lung cancer
  • 21 views
  • 23 Oct, 2022
  • 1 location
KZR-261 in Subjects With Advanced Solid Malignancies

as identify the recommended Phase 2 dose (RP2D). The study comprises a Part 1 (Dose Escalation) and a Part 2 (Dose Expansion) in solid organ tumors (melanoma/uveal melanoma, mesothelioma, colorectal

  • 0 views
  • 04 Oct, 2022
  • 3 locations
A Phase II Clinical Trial to Evaluate Safety and Efficacy of XmAb20717 in Advanced Rare Cancers

To test the safety of and effectiveness of XmAb20717 for participants with advanced rare cancers.

  • 0 views
  • 18 Oct, 2022
  • 1 location
Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers

locally advanced, recurrent, or metastatic cancer associated with one of the following cancer types: 1.) gastric/esophagogastric, 2.) colorectal, 3.) pancreatic, 4.) sarcoma, 5.) mesothelioma, 6

fludarabine
sarcoma
metastasis
cancer
gilbert's syndrome
  • 12 views
  • 04 Oct, 2022
  • 1 location
A Study of TAK-500 With or Without Pembrolizumab in Adults With Select Locally Advanced or Metastatic Solid Tumors

This study is about TAK-500, given either alone or with pembrolizumab, in adults with select locally advanced or metastatic solid tumors. The aims of the study are: to assess the safety profile of TAK-500 when given alone and when given with pembrolizumab. to assess the effects of TAK-500, when given …

monoclonal antibodies
squamous cell carcinoma
pancreatic adenocarcinoma
alopecia
carcinoma
  • 12 views
  • 04 Oct, 2022
  • 1 location
A Phase 1, Open-Label, Multi-Center, Dose Escalation and Expansion Study of HFB200301 (TNFR2 Agonist Antibody) in Adult Patients With Advanced Solid Tumors

The purpose of this study is to test the safety and tolerability of HFB200301 in patients with advanced cancers. There are two parts in this study. During the escalation part, groups of participants will receive increasing doses until a safe and tolerable dose of HFB200301 is determined. During the expansion …

squamous cell carcinoma
BRAF
measurable disease
carcinoma
systemic therapy
  • 0 views
  • 21 Oct, 2022
  • 10 locations
A Study of NX-1607 in Adults With Advanced Malignancies

This is a first-in-human Phase 1a/1b multicenter, open-label oncology study designed to evaluate the safety and anti-cancer activity of NX-1607 in patients with advanced malignancies.

fallopian tube
growth factors
measurable disease
carcinoma
systemic therapy
  • 0 views
  • 04 Oct, 2022
  • 6 locations
Improving Patient and Caregiver Understanding of Risks and Benefits of Immunotherapy for Advanced Cancer (UPLIFT)

The purpose of this study is to refine and pilot test educational material developed to educate and support patients receiving immunotherapy for advanced cancer. The intervention is an educational video and question prompt list (QPL) to promote communication between patients, caregivers, and the oncology team about the risks and benefits …

Accepts healthy volunteers
  • 0 views
  • 07 Oct, 2022
  • 1 location